ACVR1 (Activin receptor type-1)

Group: TKL
Uniprot: ACVR1_HUMAN
Domain boundary: 208 - 497


Total number of chains: 160
Spatial Dihedral Chains Representative
DFGin BLAminus 153 AF-Q04771-K1A
DFGin ABAminus 6 6T6DB
DFGin None 1 6T6DA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
6T6DB 2.56 Inactive DFGin ABAminus in-out in-in MM8 Type1 203 - 499 Q207D None 0
6T6DC 2.56 Inactive DFGin ABAminus in-out in-in MM8 Type1 205 - 498 Q207D None 11
6ZGCA 2.67 Inactive DFGin ABAminus in-out in-in H8H Type1 205 - 499 Q207D None 3
6ZGCB 2.67 Inactive DFGin ABAminus in-out in-in H8H Type1 203 - 499 Q207D None 5
6ZGCC 2.67 Inactive DFGin ABAminus in-none in-in H8H Type1 201 - 498 Q207D None 2
6ZGCD 2.67 Inactive DFGin ABAminus in-out in-in H8H Type1 203 - 498 Q207D None 3
6SZMA 1.42 Inactive DFGin BLAminus in-out in-in M2Z M2Z M2Z Allosteric Allosteric Type1 202 - 499 None None 10
5S7QB 1.53 Inactive DFGin BLAminus in-out in-in XJM LU8 XJM Allosteric Type1 Allosteric 205 - 499 Q207D None 0
AF-Q04771-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 200 - 505 None None 0
6JUXA 1.75 Inactive DFGin BLAminus in-out in-in C9U Type1 203 - 499 R206H None 0
4DYMA 2.42 Inactive DFGin BLAminus in-out in-in IYZ Type1 207 - 499 R206H None 0
6ACRA 2.01 Inactive DFGin BLAminus in-out in-in 9TO Type1 203 - 498 R206H None 0
6ACRB 2.01 Inactive DFGin BLAminus in-out in-in 9TO Type1 203 - 498 R206H None 0
7C3GA 1.802 Inactive DFGin BLAminus in-out in-in FH0 Type1 203 - 499 R206H None 0
7C3GB 1.802 Inactive DFGin BLAminus in-out in-in FH0 Type1 204 - 499 R206H None 0
3MTFA 2.15 Inactive DFGin BLAminus in-out in-in A3F Type1 203 - 498 Q207D None 0
3MTFB 2.15 Inactive DFGin BLAminus in-out in-in A3F Type1 202 - 499 Q207D None 0
3OOMA 2.0 Inactive DFGin BLAminus in-out in-in 507 Type1 203 - 499 Q207D None 0
3Q4UA 1.82 Inactive DFGin BLAminus in-out in-in LDN Type1 202 - 499 Q207D None 0
3Q4UB 1.82 Inactive DFGin BLAminus in-out in-in LDN Type1 201 - 498 Q207D None 0
3Q4UC 1.82 Inactive DFGin BLAminus in-out in-in LDN Type1 204 - 499 Q207D None 0
3Q4UD 1.82 Inactive DFGin BLAminus in-out in-in LDN Type1 201 - 499 Q207D None 0
4BGGA 2.56 Inactive DFGin BLAminus in-out in-in 844 Type1 203 - 498 Q207D None 0
4BGGB 2.56 Inactive DFGin BLAminus in-out in-in 844 Type1 203 - 498 Q207D None 0
4BGGC 2.56 Inactive DFGin BLAminus in-out in-in 844 Type1 204 - 497 Q207D None 3
4BGGD 2.56 Inactive DFGin BLAminus in-out in-in 844 Type1 204 - 498 Q207D None 0
5OXGA 2.13 Inactive DFGin BLAminus in-out in-in B4B Type1 203 - 498 Q207D None 0
5OXGB 2.13 Inactive DFGin BLAminus in-out in-in B4B Type1 203 - 498 Q207D None 0
5OXGC 2.13 Inactive DFGin BLAminus in-out in-in B4B Type1 201 - 499 Q207D None 0
5OXGD 2.13 Inactive DFGin BLAminus in-out in-in B4B Type1 204 - 499 Q207D None 0
5OY6A 2.56 Inactive DFGin BLAminus in-out in-in B4E Type1 204 - 498 Q207D None 4
5OY6B 2.56 Inactive DFGin BLAminus in-out in-in B4E Type1 203 - 498 Q207D None 4
5OY6C 2.56 Inactive DFGin BLAminus in-out in-in B4E Type1 204 - 498 Q207D None 4
5OY6D 2.56 None DFGin BLAminus in-none in-in B4E Type1 204 - 499 Q207D None 4
5S77B 1.31 Inactive DFGin BLAminus in-out in-in LU8 Type1 205 - 499 Q207D None 0
5S78B 1.3 Inactive DFGin BLAminus in-out in-in LU8 Type1 208 - 499 Q207D None 0
5S79B 1.5 Inactive DFGin BLAminus in-out in-in LU8 Type1 208 - 498 Q207D None 0
5S7GB 1.78 Inactive DFGin BLAminus in-out in-in LU8 Type1 207 - 499 Q207D None 8
5S7HB 1.3 Inactive DFGin BLAminus in-out in-in LU8 Type1 205 - 499 Q207D None 0
5S7JB 1.31 Inactive DFGin BLAminus in-out in-in LU8 Type1 206 - 499 Q207D None 0
5S7PB 1.31 Inactive DFGin BLAminus in-out in-in LU8 Type1 208 - 499 Q207D None 0
5S7WB 1.33 Inactive DFGin BLAminus in-out in-in LU8 Type1 205 - 499 Q207D None 0
5S83B 1.33 Inactive DFGin BLAminus in-out in-in LU8 Type1 205 - 499 Q207D None 0
5S84B 1.35 Inactive DFGin BLAminus in-out in-in LU8 Type1 206 - 499 Q207D None 0
5S89B 1.3 Inactive DFGin BLAminus in-out in-in LU8 Type1 205 - 499 Q207D None 0
6GI6A 1.98 Inactive DFGin BLAminus in-out in-in EZB Type1 202 - 499 Q207D None 0
6GINA 2.2 Inactive DFGin BLAminus in-out in-in IR2 Type1 204 - 499 Q207D None 0
6GINB 2.2 Inactive DFGin BLAminus in-out in-in IR2 Type1 204 - 499 Q207D None 0
6GIPA 2.17 Inactive DFGin BLAminus in-out in-in EUN Type1 204 - 499 Q207D None 0
6SRHA 1.25 Inactive DFGin BLAminus in-out in-in LU8 Type1 201 - 499 Q207D None 11
6SZMB 1.42 Inactive DFGin BLAminus in-out in-in M2Z Type1 205 - 499 None None 0
6T6DD 2.56 Inactive DFGin BLAminus in-out in-in MM8 Type1 203 - 498 Q207D None 11
6T8NA 1.77 Inactive DFGin BLAminus in-out in-in MVE Type1 203 - 498 Q207D None 0
6T8NB 1.77 Inactive DFGin BLAminus in-out in-in MVE Type1 203 - 499 Q207D None 0
6TN8A 1.63 Inactive DFGin BLAminus in-out in-in 5U6 Type1 204 - 499 None None 0
6Z36B 1.37 Inactive DFGin BLAminus in-out in-in Q5Z Type1 204 - 498 Q207D None 0
7A21A 2.14 Inactive DFGin BLAminus in-out in-in QWQ Type1 203 - 498 Q207D None 0
7A21B 2.14 Inactive DFGin BLAminus in-out in-in QWQ Type1 203 - 498 Q207D None 0
7NNSB 2.14 Inactive DFGin BLAminus in-out in-in C87 Type1 204 - 499 Q207D None 0
8C7WA 2.26 Inactive DFGin BLAminus in-out in-in U0C Type1 202 - 499 Q207D None 0
8C7ZA 2.23 Inactive DFGin BLAminus in-out in-in TZX Type1 204 - 498 Q207D None 0
8R7GA 2.09 Inactive DFGin BLAminus in-out in-in YEE Type1 205 - 499 Q207D None 0
8R7GB 2.09 Inactive DFGin BLAminus in-out in-in YEE Type1 205 - 498 Q207D None 0
8R7GC 2.09 Active DFGin BLAminus in-in in-in YEE Type1 206 - 498 Q207D None 12
8R7GD 2.09 None DFGin BLAminus in-none in-in YEE Type1 204 - 498 Q207D None 4
9D8FA 1.86 Inactive DFGin BLAminus in-out in-in A1A3C Type1 193 - 499 None None 0
9D8FB 1.86 Inactive DFGin BLAminus in-out in-in A1A3C Type1 200 - 499 None None 0
8UWRA 2.04 Inactive DFGin BLAminus in-out in-in XQX Type1 203 - 499 Q207D None 0
3H9RA 2.35 Inactive DFGin BLAminus in-out in-in TAK Type1 172 - 499 None None 13
4C02A 2.17 Inactive DFGin BLAminus in-out in-in TAK Type1 178 - 499 None None 3
6I1SA 1.52 Inactive DFGin BLAminus in-out in-in E26 Type1 172 - 499 None None 0
9D8EA 1.72 Inactive DFGin BLAminus in-out in-in A1A29 Type1 193 - 499 None None 0
9D8EB 1.72 Inactive DFGin BLAminus in-out in-in A1A29 Type1 193 - 498 None None 0
9D8ZA 1.85 Inactive DFGin BLAminus in-out in-in A1A3D Type1 203 - 499 None None 0
9D8ZB 1.85 Inactive DFGin BLAminus in-out in-in A1A3D Type1 193 - 499 None None 0
6UNQA 2.4 Inactive DFGin BLAminus in-out in-in ANP Type1 206 - 496 K493A None 0
6UNRA 2.2 Inactive DFGin BLAminus in-out in-in ANP Type1 208 - 496 None None 0
6UNSA 2.3 Active DFGin BLAminus in-in in-in LDN Type1 204 - 496 K492A,K493A None 0
6UNSB 2.3 Inactive DFGin BLAminus in-out in-in LDN Type1 204 - 496 K492A,K493A None 0
6EIXA 2.3 Inactive DFGin BLAminus in-out in-in A3F Type1 192 - 503 Q207E None 0
5S7BB 1.32 Inactive DFGin BLAminus in-out in-in LU8 XH7 Type1 Allosteric 205 - 499 Q207D None 0
5S7CB 1.31 Inactive DFGin BLAminus in-out in-in LU8 T5Y Type1 Allosteric 205 - 499 Q207D None 0
5S7DB 1.31 Inactive DFGin BLAminus in-out in-in LU8 XHD Type1 Allosteric 205 - 499 Q207D None 0
5S7EB 1.32 Inactive DFGin BLAminus in-out in-in LU8 XEA Type1 Allosteric 205 - 499 Q207D None 0
5S7KB 1.31 Inactive DFGin BLAminus in-out in-in LU8 XEJ Type1 Allosteric 205 - 499 None None 0
5S7MB 1.32 Inactive DFGin BLAminus in-out in-in LU8 HVK Type1 Allosteric 208 - 499 Q207D None 0
5S7NB 1.3 Inactive DFGin BLAminus in-out in-in LU8 2AI Type1 Allosteric 207 - 499 Q207D None 0
5S7SB 1.3 Inactive DFGin BLAminus in-out in-in LU8 09V Type1 Allosteric 205 - 499 Q207D None 0
5S7VB 1.31 Inactive DFGin BLAminus in-out in-in LU8 XH1 Type1 Allosteric 205 - 499 Q207D None 0
5S7XB 1.3 Inactive DFGin BLAminus in-out in-in LU8 LGA Type1 Allosteric 205 - 499 Q207D None 0
5S7ZB 1.3 Inactive DFGin BLAminus in-out in-in LU8 BYZ Type1 Allosteric 205 - 499 Q207D None 0
5S82B 1.71 Inactive DFGin BLAminus in-out in-in LU8 LAC Type1 Allosteric 205 - 499 Q207D None 7
5S86B 1.31 Inactive DFGin BLAminus in-out in-in LU8 XK7 Type1 Allosteric 205 - 499 Q207D None 0
5S87B 1.3 Inactive DFGin BLAminus in-out in-in LU8 XKD Type1 Allosteric 205 - 499 Q207D None 0
5S88B 1.31 Inactive DFGin BLAminus in-out in-in LU8 XKS Type1 Allosteric 205 - 499 Q207D None 0
5S8AB 1.3 Inactive DFGin BLAminus in-out in-in LU8 XKY Type1 Allosteric 205 - 499 Q207D None 0
8PODA 2.59 Inactive DFGin BLAminus in-out in-in 7IO F Type1 Allosteric 172 - 498 None None 0
5S75B 1.3 Inactive DFGin BLAminus in-out in-in LU8 HUH HUH Type1 Allosteric Allosteric 205 - 499 Q207D None 0
5S79A 1.5 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 12
5S7AB 1.3 Inactive DFGin BLAminus in-out in-in LU8 T5V T5V Type1 Allosteric Allosteric 205 - 499 Q207D None 0
5S7EA 1.32 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
5S7FA 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
5S7FB 1.31 Inactive DFGin BLAminus in-out in-in LU8 XH4 XH4 Type1 Allosteric Allosteric 205 - 499 Q207D None 0
5S7GA 1.78 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 498 Q207D None 13
5S7OA 1.43 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 201 - 499 Q207D None 11
5S7QA 1.53 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
5S7UA 1.59 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
5S7UB 1.59 Inactive DFGin BLAminus in-out in-in LU8 XGY XGY Type1 Allosteric Allosteric 205 - 499 Q207D None 9
5S7VA 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 12
5S7WA 1.33 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
5S7YA 1.37 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
5S80A 1.67 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
5S80B 1.67 Inactive DFGin BLAminus in-out in-in LU8 XGM XGM Type1 Allosteric Allosteric 205 - 499 Q207D None 0
5S82A 1.71 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
5S87A 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 201 - 499 Q207D None 13
5S88A 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
5S9KA 1.35 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 201 - 499 Q207D None 13
6SRHB 1.25 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 205 - 499 Q207D None 0
6Z36A 1.37 Inactive DFGin BLAminus in-out in-in Q5Z Q5Z Q5Z Type1 Allosteric Allosteric 202 - 499 Q207D None 12
5S77A 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 BAQ Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
5S7DA 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XHD Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 12
5S7JA 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XHG Type1 Allosteric Allosteric Allosteric 201 - 499 Q207D None 11
5S7KA 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XEJ Type1 Allosteric Allosteric Allosteric 202 - 499 None None 11
5S7LA 1.36 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XHJ Type1 Allosteric Allosteric Allosteric 201 - 499 Q207D None 11
5S7MA 1.32 Inactive DFGin BLAminus in-out in-in LU8 LU8 HVK HVK Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 10
5S7NA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 2AI Type1 Allosteric Allosteric Allosteric 201 - 499 Q207D None 13
5S7PA 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 V1L Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
5S7SA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 09V Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 9
5S7TB 1.3 Inactive DFGin BLAminus in-out in-in LU8 XGJ XGJ XGJ Type1 Allosteric Allosteric Allosteric 205 - 498 Q207D None 0
5S7XA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 LGA Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
5S86A 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XK7 Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
5S89A 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XKV Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
5S8AA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XKY Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
5S8BB 1.64 Inactive DFGin BLAminus in-out in-in LU8 XFV XFV XFV Type1 Allosteric Allosteric Allosteric 205 - 499 Q207D None 0
5S75A 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HUH HUH Type1 Allosteric Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
5S7AA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 T5V T5V Type1 Allosteric Allosteric Allosteric Allosteric 201 - 499 Q207D None 12
5S7BA 1.32 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XH7 XH7 Type1 Allosteric Allosteric Allosteric Allosteric 202 - 499 Q207D None 10
5S7HA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HVB HVB Type1 Allosteric Allosteric Allosteric Allosteric 201 - 499 Q207D None 12
5S7ZA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 BYZ BYZ Type1 Allosteric Allosteric Allosteric Allosteric 202 - 499 Q207D None 9
5S81B 1.43 Inactive DFGin BLAminus in-out in-in LU8 XJV XJV XJV XJV Type1 Allosteric Allosteric Allosteric Allosteric 208 - 499 Q207D None 0
5S7CA 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 T5Y T5Y T5Y Type1 Allosteric Allosteric Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
5S7IA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HV2 HV2 HV2 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric 201 - 499 Q207D None 13
5S7TA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XGJ XGJ XGJ Type1 Allosteric Allosteric Allosteric Allosteric Allosteric 202 - 499 Q207D None 12
5S7YB 1.37 Inactive DFGin BLAminus in-out in-in LU8 XJP XJP XJP XJP XJP Type1 Allosteric Allosteric Allosteric Allosteric Allosteric 207 - 499 Q207D None 0
5S7RB 1.46 Inactive DFGin BLAminus in-out in-in LU8 XGS XGS XGS XGS XGS XGS Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric 205 - 499 Q207D None 0
5S85A 1.33 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XK4 XK4 XK4 XK4 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
5S8BA 1.64 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XFV XFV XFV XFV Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric 201 - 499 Q207D None 13
5S7RA 1.46 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XGS XGS XGS XGS XGS Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
5S7IB 1.3 Inactive DFGin BLAminus in-out in-in LU8 HV2 HV2 HV2 HV2 HV2 HV2 HV2 HV2 HV2 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric 205 - 499 Q207D None 0
5S78A 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XGV XGV XGV Type1 Allosteric Allosteric Allosteric Allosteric Type1 202 - 499 Q207D None 11
5S81A 1.43 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XJV XJV Type1 Allosteric Allosteric Allosteric Type1 202 - 499 Q207D None 13
5S76A 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 02A 02A Type1 Allosteric Allosteric Allosteric Type1.5_Back 202 - 499 Q207D None 13
5S7LB 1.36 Inactive DFGin BLAminus in-out in-in LU8 XHJ XHJ XHJ XHJ Type1 Allosteric Allosteric Allosteric Type3 205 - 499 Q207D None 0
5S84A 1.35 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XK1 Type1 Allosteric Allosteric Type1 201 - 499 Q207D None 13
5S83A 1.33 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XJY Type1 Allosteric Allosteric Type3 202 - 499 Q207D None 13
5S7OB 1.43 Inactive DFGin BLAminus in-out in-in LU8 XJJ Type1 Type1 205 - 499 Q207D None 0
5S85B 1.33 Inactive DFGin BLAminus in-out in-in LU8 XK4 XK4 XK4 Type1 Type1 Allosteric Allosteric 207 - 499 Q207D None 0
5S76B 1.31 Inactive DFGin BLAminus in-out in-in LU8 02A Type1 Type1.5_Back 205 - 499 Q207D None 0
5S9KB 1.35 Inactive DFGin BLAminus in-out in-in LU8 YV4 Type1 Type3 205 - 499 Q207D None 0
6T6DA 2.56 Inactive DFGin None in-in in-in MM8 Type1 204 - 499 Q207D None 4

ACVR1 (Activin receptor type-1)

Group: TKL
Total number of chains: 160
Spatial Dihedral Chains Representative
DFGin BLAminus 153 AF-Q04771-K1A
DFGin ABAminus 6 6T6DB
DFGin None 1 6T6DA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens ACVR1_HUMAN 6T6DB 2.56 Inactive DFGin ABAminus in-out in-in MM8 Type1 203 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 6T6DC 2.56 Inactive DFGin ABAminus in-out in-in MM8 Type1 205 - 498 Q207D None 11
Homo sapiens ACVR1_HUMAN 6ZGCA 2.67 Inactive DFGin ABAminus in-out in-in H8H Type1 205 - 499 Q207D None 3
Homo sapiens ACVR1_HUMAN 6ZGCB 2.67 Inactive DFGin ABAminus in-out in-in H8H Type1 203 - 499 Q207D None 5
Homo sapiens ACVR1_HUMAN 6ZGCC 2.67 Inactive DFGin ABAminus in-none in-in H8H Type1 201 - 498 Q207D None 2
Homo sapiens ACVR1_HUMAN 6ZGCD 2.67 Inactive DFGin ABAminus in-out in-in H8H Type1 203 - 498 Q207D None 3
Homo sapiens ACVR1_HUMAN 6SZMA 1.42 Inactive DFGin BLAminus in-out in-in M2Z M2Z M2Z Allosteric Allosteric Type1 202 - 499 None None 10
Homo sapiens ACVR1_HUMAN 5S7QB 1.53 Inactive DFGin BLAminus in-out in-in XJM LU8 XJM Allosteric Type1 Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN AF-Q04771-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 200 - 505 None None 0
Homo sapiens ACVR1_HUMAN 6JUXA 1.75 Inactive DFGin BLAminus in-out in-in C9U Type1 203 - 499 R206H None 0
Homo sapiens ACVR1_HUMAN 4DYMA 2.42 Inactive DFGin BLAminus in-out in-in IYZ Type1 207 - 499 R206H None 0
Homo sapiens ACVR1_HUMAN 6ACRA 2.01 Inactive DFGin BLAminus in-out in-in 9TO Type1 203 - 498 R206H None 0
Homo sapiens ACVR1_HUMAN 6ACRB 2.01 Inactive DFGin BLAminus in-out in-in 9TO Type1 203 - 498 R206H None 0
Homo sapiens ACVR1_HUMAN 7C3GA 1.802 Inactive DFGin BLAminus in-out in-in FH0 Type1 203 - 499 R206H None 0
Homo sapiens ACVR1_HUMAN 7C3GB 1.802 Inactive DFGin BLAminus in-out in-in FH0 Type1 204 - 499 R206H None 0
Homo sapiens ACVR1_HUMAN 3MTFA 2.15 Inactive DFGin BLAminus in-out in-in A3F Type1 203 - 498 Q207D None 0
Homo sapiens ACVR1_HUMAN 3MTFB 2.15 Inactive DFGin BLAminus in-out in-in A3F Type1 202 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 3OOMA 2.0 Inactive DFGin BLAminus in-out in-in 507 Type1 203 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 3Q4UA 1.82 Inactive DFGin BLAminus in-out in-in LDN Type1 202 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 3Q4UB 1.82 Inactive DFGin BLAminus in-out in-in LDN Type1 201 - 498 Q207D None 0
Homo sapiens ACVR1_HUMAN 3Q4UC 1.82 Inactive DFGin BLAminus in-out in-in LDN Type1 204 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 3Q4UD 1.82 Inactive DFGin BLAminus in-out in-in LDN Type1 201 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 4BGGA 2.56 Inactive DFGin BLAminus in-out in-in 844 Type1 203 - 498 Q207D None 0
Homo sapiens ACVR1_HUMAN 4BGGB 2.56 Inactive DFGin BLAminus in-out in-in 844 Type1 203 - 498 Q207D None 0
Homo sapiens ACVR1_HUMAN 4BGGC 2.56 Inactive DFGin BLAminus in-out in-in 844 Type1 204 - 497 Q207D None 3
Homo sapiens ACVR1_HUMAN 4BGGD 2.56 Inactive DFGin BLAminus in-out in-in 844 Type1 204 - 498 Q207D None 0
Homo sapiens ACVR1_HUMAN 5OXGA 2.13 Inactive DFGin BLAminus in-out in-in B4B Type1 203 - 498 Q207D None 0
Homo sapiens ACVR1_HUMAN 5OXGB 2.13 Inactive DFGin BLAminus in-out in-in B4B Type1 203 - 498 Q207D None 0
Homo sapiens ACVR1_HUMAN 5OXGC 2.13 Inactive DFGin BLAminus in-out in-in B4B Type1 201 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5OXGD 2.13 Inactive DFGin BLAminus in-out in-in B4B Type1 204 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5OY6A 2.56 Inactive DFGin BLAminus in-out in-in B4E Type1 204 - 498 Q207D None 4
Homo sapiens ACVR1_HUMAN 5OY6B 2.56 Inactive DFGin BLAminus in-out in-in B4E Type1 203 - 498 Q207D None 4
Homo sapiens ACVR1_HUMAN 5OY6C 2.56 Inactive DFGin BLAminus in-out in-in B4E Type1 204 - 498 Q207D None 4
Homo sapiens ACVR1_HUMAN 5OY6D 2.56 None DFGin BLAminus in-none in-in B4E Type1 204 - 499 Q207D None 4
Homo sapiens ACVR1_HUMAN 5S77B 1.31 Inactive DFGin BLAminus in-out in-in LU8 Type1 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S78B 1.3 Inactive DFGin BLAminus in-out in-in LU8 Type1 208 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S79B 1.5 Inactive DFGin BLAminus in-out in-in LU8 Type1 208 - 498 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7GB 1.78 Inactive DFGin BLAminus in-out in-in LU8 Type1 207 - 499 Q207D None 8
Homo sapiens ACVR1_HUMAN 5S7HB 1.3 Inactive DFGin BLAminus in-out in-in LU8 Type1 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7JB 1.31 Inactive DFGin BLAminus in-out in-in LU8 Type1 206 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7PB 1.31 Inactive DFGin BLAminus in-out in-in LU8 Type1 208 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7WB 1.33 Inactive DFGin BLAminus in-out in-in LU8 Type1 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S83B 1.33 Inactive DFGin BLAminus in-out in-in LU8 Type1 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S84B 1.35 Inactive DFGin BLAminus in-out in-in LU8 Type1 206 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S89B 1.3 Inactive DFGin BLAminus in-out in-in LU8 Type1 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 6GI6A 1.98 Inactive DFGin BLAminus in-out in-in EZB Type1 202 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 6GINA 2.2 Inactive DFGin BLAminus in-out in-in IR2 Type1 204 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 6GINB 2.2 Inactive DFGin BLAminus in-out in-in IR2 Type1 204 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 6GIPA 2.17 Inactive DFGin BLAminus in-out in-in EUN Type1 204 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 6SRHA 1.25 Inactive DFGin BLAminus in-out in-in LU8 Type1 201 - 499 Q207D None 11
Homo sapiens ACVR1_HUMAN 6SZMB 1.42 Inactive DFGin BLAminus in-out in-in M2Z Type1 205 - 499 None None 0
Homo sapiens ACVR1_HUMAN 6T6DD 2.56 Inactive DFGin BLAminus in-out in-in MM8 Type1 203 - 498 Q207D None 11
Homo sapiens ACVR1_HUMAN 6T8NA 1.77 Inactive DFGin BLAminus in-out in-in MVE Type1 203 - 498 Q207D None 0
Homo sapiens ACVR1_HUMAN 6T8NB 1.77 Inactive DFGin BLAminus in-out in-in MVE Type1 203 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 6TN8A 1.63 Inactive DFGin BLAminus in-out in-in 5U6 Type1 204 - 499 None None 0
Homo sapiens ACVR1_HUMAN 6Z36B 1.37 Inactive DFGin BLAminus in-out in-in Q5Z Type1 204 - 498 Q207D None 0
Homo sapiens ACVR1_HUMAN 7A21A 2.14 Inactive DFGin BLAminus in-out in-in QWQ Type1 203 - 498 Q207D None 0
Homo sapiens ACVR1_HUMAN 7A21B 2.14 Inactive DFGin BLAminus in-out in-in QWQ Type1 203 - 498 Q207D None 0
Homo sapiens ACVR1_HUMAN 7NNSB 2.14 Inactive DFGin BLAminus in-out in-in C87 Type1 204 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 8C7WA 2.26 Inactive DFGin BLAminus in-out in-in U0C Type1 202 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 8C7ZA 2.23 Inactive DFGin BLAminus in-out in-in TZX Type1 204 - 498 Q207D None 0
Homo sapiens ACVR1_HUMAN 8R7GA 2.09 Inactive DFGin BLAminus in-out in-in YEE Type1 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 8R7GB 2.09 Inactive DFGin BLAminus in-out in-in YEE Type1 205 - 498 Q207D None 0
Homo sapiens ACVR1_HUMAN 8R7GC 2.09 Active DFGin BLAminus in-in in-in YEE Type1 206 - 498 Q207D None 12
Homo sapiens ACVR1_HUMAN 8R7GD 2.09 None DFGin BLAminus in-none in-in YEE Type1 204 - 498 Q207D None 4
Homo sapiens ACVR1_HUMAN 9D8FA 1.86 Inactive DFGin BLAminus in-out in-in A1A3C Type1 193 - 499 None None 0
Homo sapiens ACVR1_HUMAN 9D8FB 1.86 Inactive DFGin BLAminus in-out in-in A1A3C Type1 200 - 499 None None 0
Homo sapiens ACVR1_HUMAN 8UWRA 2.04 Inactive DFGin BLAminus in-out in-in XQX Type1 203 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 3H9RA 2.35 Inactive DFGin BLAminus in-out in-in TAK Type1 172 - 499 None None 13
Homo sapiens ACVR1_HUMAN 4C02A 2.17 Inactive DFGin BLAminus in-out in-in TAK Type1 178 - 499 None None 3
Homo sapiens ACVR1_HUMAN 6I1SA 1.52 Inactive DFGin BLAminus in-out in-in E26 Type1 172 - 499 None None 0
Homo sapiens ACVR1_HUMAN 9D8EA 1.72 Inactive DFGin BLAminus in-out in-in A1A29 Type1 193 - 499 None None 0
Homo sapiens ACVR1_HUMAN 9D8EB 1.72 Inactive DFGin BLAminus in-out in-in A1A29 Type1 193 - 498 None None 0
Homo sapiens ACVR1_HUMAN 9D8ZA 1.85 Inactive DFGin BLAminus in-out in-in A1A3D Type1 203 - 499 None None 0
Homo sapiens ACVR1_HUMAN 9D8ZB 1.85 Inactive DFGin BLAminus in-out in-in A1A3D Type1 193 - 499 None None 0
Homo sapiens ACVR1_HUMAN 6UNQA 2.4 Inactive DFGin BLAminus in-out in-in ANP Type1 206 - 496 K493A None 0
Homo sapiens ACVR1_HUMAN 6UNRA 2.2 Inactive DFGin BLAminus in-out in-in ANP Type1 208 - 496 None None 0
Homo sapiens ACVR1_HUMAN 6UNSA 2.3 Active DFGin BLAminus in-in in-in LDN Type1 204 - 496 K492A,K493A None 0
Homo sapiens ACVR1_HUMAN 6UNSB 2.3 Inactive DFGin BLAminus in-out in-in LDN Type1 204 - 496 K492A,K493A None 0
Homo sapiens ACVR1_HUMAN 6EIXA 2.3 Inactive DFGin BLAminus in-out in-in A3F Type1 192 - 503 Q207E None 0
Homo sapiens ACVR1_HUMAN 5S7BB 1.32 Inactive DFGin BLAminus in-out in-in LU8 XH7 Type1 Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7CB 1.31 Inactive DFGin BLAminus in-out in-in LU8 T5Y Type1 Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7DB 1.31 Inactive DFGin BLAminus in-out in-in LU8 XHD Type1 Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7EB 1.32 Inactive DFGin BLAminus in-out in-in LU8 XEA Type1 Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7KB 1.31 Inactive DFGin BLAminus in-out in-in LU8 XEJ Type1 Allosteric 205 - 499 None None 0
Homo sapiens ACVR1_HUMAN 5S7MB 1.32 Inactive DFGin BLAminus in-out in-in LU8 HVK Type1 Allosteric 208 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7NB 1.3 Inactive DFGin BLAminus in-out in-in LU8 2AI Type1 Allosteric 207 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7SB 1.3 Inactive DFGin BLAminus in-out in-in LU8 09V Type1 Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7VB 1.31 Inactive DFGin BLAminus in-out in-in LU8 XH1 Type1 Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7XB 1.3 Inactive DFGin BLAminus in-out in-in LU8 LGA Type1 Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7ZB 1.3 Inactive DFGin BLAminus in-out in-in LU8 BYZ Type1 Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S82B 1.71 Inactive DFGin BLAminus in-out in-in LU8 LAC Type1 Allosteric 205 - 499 Q207D None 7
Homo sapiens ACVR1_HUMAN 5S86B 1.31 Inactive DFGin BLAminus in-out in-in LU8 XK7 Type1 Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S87B 1.3 Inactive DFGin BLAminus in-out in-in LU8 XKD Type1 Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S88B 1.31 Inactive DFGin BLAminus in-out in-in LU8 XKS Type1 Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S8AB 1.3 Inactive DFGin BLAminus in-out in-in LU8 XKY Type1 Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 8PODA 2.59 Inactive DFGin BLAminus in-out in-in 7IO F Type1 Allosteric 172 - 498 None None 0
Homo sapiens ACVR1_HUMAN 5S75B 1.3 Inactive DFGin BLAminus in-out in-in LU8 HUH HUH Type1 Allosteric Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S79A 1.5 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 12
Homo sapiens ACVR1_HUMAN 5S7AB 1.3 Inactive DFGin BLAminus in-out in-in LU8 T5V T5V Type1 Allosteric Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7EA 1.32 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7FA 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7FB 1.31 Inactive DFGin BLAminus in-out in-in LU8 XH4 XH4 Type1 Allosteric Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7GA 1.78 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 498 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7OA 1.43 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 201 - 499 Q207D None 11
Homo sapiens ACVR1_HUMAN 5S7QA 1.53 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7UA 1.59 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7UB 1.59 Inactive DFGin BLAminus in-out in-in LU8 XGY XGY Type1 Allosteric Allosteric 205 - 499 Q207D None 9
Homo sapiens ACVR1_HUMAN 5S7VA 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 12
Homo sapiens ACVR1_HUMAN 5S7WA 1.33 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7YA 1.37 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S80A 1.67 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S80B 1.67 Inactive DFGin BLAminus in-out in-in LU8 XGM XGM Type1 Allosteric Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S82A 1.71 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S87A 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 201 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S88A 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S9KA 1.35 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 201 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 6SRHB 1.25 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 6Z36A 1.37 Inactive DFGin BLAminus in-out in-in Q5Z Q5Z Q5Z Type1 Allosteric Allosteric 202 - 499 Q207D None 12
Homo sapiens ACVR1_HUMAN 5S77A 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 BAQ Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7DA 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XHD Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 12
Homo sapiens ACVR1_HUMAN 5S7JA 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XHG Type1 Allosteric Allosteric Allosteric 201 - 499 Q207D None 11
Homo sapiens ACVR1_HUMAN 5S7KA 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XEJ Type1 Allosteric Allosteric Allosteric 202 - 499 None None 11
Homo sapiens ACVR1_HUMAN 5S7LA 1.36 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XHJ Type1 Allosteric Allosteric Allosteric 201 - 499 Q207D None 11
Homo sapiens ACVR1_HUMAN 5S7MA 1.32 Inactive DFGin BLAminus in-out in-in LU8 LU8 HVK HVK Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 10
Homo sapiens ACVR1_HUMAN 5S7NA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 2AI Type1 Allosteric Allosteric Allosteric 201 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7PA 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 V1L Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7SA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 09V Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 9
Homo sapiens ACVR1_HUMAN 5S7TB 1.3 Inactive DFGin BLAminus in-out in-in LU8 XGJ XGJ XGJ Type1 Allosteric Allosteric Allosteric 205 - 498 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7XA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 LGA Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S86A 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XK7 Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S89A 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XKV Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S8AA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XKY Type1 Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S8BB 1.64 Inactive DFGin BLAminus in-out in-in LU8 XFV XFV XFV Type1 Allosteric Allosteric Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S75A 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HUH HUH Type1 Allosteric Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7AA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 T5V T5V Type1 Allosteric Allosteric Allosteric Allosteric 201 - 499 Q207D None 12
Homo sapiens ACVR1_HUMAN 5S7BA 1.32 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XH7 XH7 Type1 Allosteric Allosteric Allosteric Allosteric 202 - 499 Q207D None 10
Homo sapiens ACVR1_HUMAN 5S7HA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HVB HVB Type1 Allosteric Allosteric Allosteric Allosteric 201 - 499 Q207D None 12
Homo sapiens ACVR1_HUMAN 5S7ZA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 BYZ BYZ Type1 Allosteric Allosteric Allosteric Allosteric 202 - 499 Q207D None 9
Homo sapiens ACVR1_HUMAN 5S81B 1.43 Inactive DFGin BLAminus in-out in-in LU8 XJV XJV XJV XJV Type1 Allosteric Allosteric Allosteric Allosteric 208 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7CA 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 T5Y T5Y T5Y Type1 Allosteric Allosteric Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7IA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HV2 HV2 HV2 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric 201 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7TA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XGJ XGJ XGJ Type1 Allosteric Allosteric Allosteric Allosteric Allosteric 202 - 499 Q207D None 12
Homo sapiens ACVR1_HUMAN 5S7YB 1.37 Inactive DFGin BLAminus in-out in-in LU8 XJP XJP XJP XJP XJP Type1 Allosteric Allosteric Allosteric Allosteric Allosteric 207 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S7RB 1.46 Inactive DFGin BLAminus in-out in-in LU8 XGS XGS XGS XGS XGS XGS Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S85A 1.33 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XK4 XK4 XK4 XK4 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S8BA 1.64 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XFV XFV XFV XFV Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric 201 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7RA 1.46 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XGS XGS XGS XGS XGS Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7IB 1.3 Inactive DFGin BLAminus in-out in-in LU8 HV2 HV2 HV2 HV2 HV2 HV2 HV2 HV2 HV2 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S78A 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XGV XGV XGV Type1 Allosteric Allosteric Allosteric Allosteric Type1 202 - 499 Q207D None 11
Homo sapiens ACVR1_HUMAN 5S81A 1.43 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XJV XJV Type1 Allosteric Allosteric Allosteric Type1 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S76A 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 02A 02A Type1 Allosteric Allosteric Allosteric Type1.5_Back 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7LB 1.36 Inactive DFGin BLAminus in-out in-in LU8 XHJ XHJ XHJ XHJ Type1 Allosteric Allosteric Allosteric Type3 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S84A 1.35 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XK1 Type1 Allosteric Allosteric Type1 201 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S83A 1.33 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XJY Type1 Allosteric Allosteric Type3 202 - 499 Q207D None 13
Homo sapiens ACVR1_HUMAN 5S7OB 1.43 Inactive DFGin BLAminus in-out in-in LU8 XJJ Type1 Type1 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S85B 1.33 Inactive DFGin BLAminus in-out in-in LU8 XK4 XK4 XK4 Type1 Type1 Allosteric Allosteric 207 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S76B 1.31 Inactive DFGin BLAminus in-out in-in LU8 02A Type1 Type1.5_Back 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 5S9KB 1.35 Inactive DFGin BLAminus in-out in-in LU8 YV4 Type1 Type3 205 - 499 Q207D None 0
Homo sapiens ACVR1_HUMAN 6T6DA 2.56 Inactive DFGin None in-in in-in MM8 Type1 204 - 499 Q207D None 4

ACVR1 (Activin receptor type-1)

No non-human structures known.