NEK / All / All

Total number of chains: 90
Active chains: 22
Total number of genes: 11
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 25 27.8% 9NFQC
DFGin BLAminus 23 25.6% AF-Q96PY6-K1A
None None 20 22.2% 2W5AA
DFGout None 13 14.4% 8SXNA
DFGinter BABtrans 4 4.4% 4B9DB
DFGinter None 2 2.2% 2W5BA
DFGout BBAminus 2 2.2% 8WS0B
DFGin BLBminus 1 1.1% 5M53A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
NEK NEK1 NEK1_HUMAN AF-Q96PY6-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 266 0 None None Serine/threonine-protein kinase Nek1
NEK NEK1 NEK1_HUMAN AF-Q96PY6-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 266 0 None None Serine/threonine-protein kinase Nek1
NEK NEK1 NEK1_HUMAN 4APCA 2.1 Inactive DFGinter‑BABtrans out-none out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 1 - 284 0 None T162A Serine/threonine-protein kinase Nek1
NEK NEK1 NEK1_HUMAN 4APCB 2.1 Inactive DFGinter‑BABtrans out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 1 - 284 0 None T162A Serine/threonine-protein kinase Nek1
NEK NEK1 NEK1_HUMAN 4B9DA 1.9 Inactive DFGinter‑BABtrans out-none out-out nonTYR APEdihe_aaiii APEdist_oooo CK7 Type1 1 - 284 0 None T162A Serine/threonine-protein kinase Nek1
NEK NEK1 NEK1_HUMAN 4B9DB 1.9 Inactive DFGinter‑BABtrans out-out out-out nonTYR APEdihe_aaiii APEdist_oooo CK7 Type1 1 - 284 0 None T162A Serine/threonine-protein kinase Nek1
NEK NEK10 NEK10_HUMAN AF-Q6ZWH5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 511 - 793 0 None None Serine/threonine-protein kinase Nek10
NEK NEK10 NEK10_HUMAN AF-Q6ZWH5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 511 - 793 0 None None Serine/threonine-protein kinase Nek10
NEK NEK11 NEK11_HUMAN AF-Q8NG66-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 21 - 295 0 None None Serine/threonine-protein kinase Nek11
NEK NEK11 NEK11_HUMAN AF-Q8NG66-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 21 - 295 0 None None Serine/threonine-protein kinase Nek11
NEK NEK2 NEK2_HUMAN AF-P51955-K1A -1.0 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 279 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN AF-P51955-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 279 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 5M53A 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 7GJ Type1 7 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2XKDA 1.96 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnnn T3M Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2XKEA 2.203 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanio APEdist_nnnn WI2 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2XKFA 2.35 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnno BX1 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 5M51A 1.899 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaioo APEdist_nnno NU6 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 5M57A 2.3 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaioo APEdist_nnno 4SP Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2W5BA 2.4 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiio APEdist_oooo AGS ATPlike 3 - 271 0 None T175A Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2W5HA 2.33 Inactive DFGinter‑None out-none none-out nonTYR APEdihe_aaiio APEdist_iooo No_ligand No_ligand 3 - 271 0 None T175A Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2XK3A 2.2 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno XK3 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2XK4A 2.1 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nooo OL2 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2XK8A 2.001 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno 5R1 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2XNPA 1.98 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nooo WCX Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 4AFEA 2.597 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnoo GGY Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 4A4XA 2.4 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnoo JUP Type1 3 - 271 0 None T170E,S171D,T175E Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2W5AA 1.55 Inactive None‑None out-out out-out nonTYR APEdihe_aaiio APEdist_oooo ADP ATPlike 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2WQOA 2.167 Inactive None‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnnn VGK Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2XK6A 2.2 Inactive None‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno EQH Type1 4 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2XK7A 1.992 Inactive None‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno 30E Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2XKCA 2.5 Inactive None‑None out-none none-out nonTYR APEdihe_aaiio APEdist_nnnn 4VQ Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2XNMA 1.85 Inactive None‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nooo WGZ Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2XNNA 2.5 Inactive None‑None out-none none-out nonTYR APEdihe_aaioo APEdist_nnno 430 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2XNOA 1.98 Inactive None‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno ED8 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 5M55A 2.4 Inactive None‑None out-none none-out nonTYR APEdihe_aanoo APEdist_nnnn 7GG Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 6SGDA 2.0 Inactive None‑None out-none none-out nonTYR APEdihe_aaiio APEdist_nnnn LD5 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 6SGHA 3.0 Inactive None‑None out-none none-none nonTYR APEdihe_aannn APEdist_nnnn LCW Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 6SGIA 2.3 Inactive None‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno LCB Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 6SGKA 2.0 Inactive None‑None out-none none-out nonTYR APEdihe_aaiio APEdist_nnnn LCQ Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 6SK9A 2.0 Inactive None‑None out-none none-out nonTYR APEdihe_aaioo APEdist_nnnn F9N Type1 4 - 271 0 None None Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN 2JAVA 2.2 Inactive None‑None out-out none-out nonTYR APEdihe_aaooo APEdist_nnnn 5Z5 Type1 3 - 271 0 None T175A Serine/threonine-protein kinase Nek2
NEK NEK3 NEK3_HUMAN AF-P51956-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 265 0 None None Serine/threonine-protein kinase Nek3
NEK NEK3 NEK3_HUMAN AF-P51956-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 265 0 None None Serine/threonine-protein kinase Nek3
NEK NEK4 NEK4_HUMAN AF-P51957-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 269 0 None None Serine/threonine-protein kinase Nek4
NEK NEK4 NEK4_HUMAN AF-P51957-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 269 0 None None Serine/threonine-protein kinase Nek4
NEK NEK5 NEK5_HUMAN AF-Q6P3R8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 267 0 None None Serine/threonine-protein kinase Nek5
NEK NEK5 NEK5_HUMAN AF-Q6P3R8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 267 0 None None Serine/threonine-protein kinase Nek5
NEK NEK6 NEK6_HUMAN AF-Q9HC98-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 37 - 313 0 None None Serine/threonine-protein kinase Nek6
NEK NEK6 NEK6_HUMAN AF-Q9HC98-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 37 - 313 0 None None Serine/threonine-protein kinase Nek6
NEK NEK7 NEK7_HUMAN AF-Q8TDX7-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 302 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN AF-Q8TDX7-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 302 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 9H59C 3.4 Inactive DFGin‑BLAminus out-out out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 23 - 302 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 9NFQC 3.25 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioo APEdist_oooo ADP ATPlike 20 - 300 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 2WQNA 2.3 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanno APEdist_nnnn ADP ATPlike 21 - 300 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8EJ4K 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8EJ4L 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8EJ4M 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8EJ4N 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8EJ4O 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8EJ4P 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8EJ4Q 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8EJ4R 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8EJ4S 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8EJ4T 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 2WQMA 2.1 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 20 - 300 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 6S76B 3.38 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaino APEdist_nnoo No_ligand No_ligand 20 - 300 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 6S76C 3.38 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanoo APEdist_nnnn No_ligand No_ligand 20 - 300 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 6S73A 3.5 Inactive DFGin‑None out-none out-out nonTYR APEdihe_aaiio APEdist_nooo F9N Type1 21 - 300 0 None L86H,Y97F,L180F Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 6S73B 3.5 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnoo F9N Type1 20 - 300 0 None L86H,Y97F,L180F Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 6S73C 3.5 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn F9N Type1 26 - 300 0 None L86H,Y97F,L180F Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 6S75B 3.3 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaino APEdist_nnno F9N Type1 20 - 300 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 6S75C 3.3 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn F9N Type1 22 - 300 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8WS0B 2.12 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 19 - 299 0 None S195D Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8WS1B 2.4 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 20 - 300 0 None D161N Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 5DE2A 2.78 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaooo APEdist_nnno No_ligand No_ligand 20 - 300 0 None Y97F Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 6S75D 3.3 Inactive DFGout‑None out-none none-out nonTYR APEdihe_aanoo APEdist_nnnn No_ligand No_ligand 28 - 299 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8WS0A 2.12 Inactive DFGout‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 20 - 300 0 None S195D Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8SXNA 4.04 Inactive DFGout‑None out-na out-out nonTYR APEdihe_aaioo APEdist_oiio No_ligand No_ligand 19 - 302 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8SXNB 4.04 Inactive DFGout‑None out-na out-out nonTYR APEdihe_aaioo APEdist_oiio No_ligand No_ligand 19 - 302 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8WS1A 2.4 Inactive DFGout‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 20 - 300 0 None D161N Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 6S75A 3.3 Inactive DFGout‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn F9N Type1 19 - 300 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 6NPYB 3.8 Inactive None‑None none-none none-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 113 - 300 0 None L54R,V58K,P59T,K87A,A99V,S100C,E103T,D104G Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 5DE2B 2.78 Inactive None‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 20 - 300 0 None Y97F Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 6S73D 3.5 Inactive None‑None out-none none-out nonTYR APEdihe_aanoo APEdist_nnnn No_ligand No_ligand 23 - 300 0 None L86H,Y97F,L180F Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 6S76A 3.38 Inactive None‑None out-none none-out nonTYR APEdihe_aaiio APEdist_nnno No_ligand No_ligand 21 - 300 0 None None Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 6S76D 3.38 Inactive None‑None out-none none-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 25 - 300 0 None None Serine/threonine-protein kinase Nek7
NEK NEK8 NEK8_HUMAN AF-Q86SG6-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 266 0 None None Serine/threonine-protein kinase Nek8
NEK NEK8 NEK8_HUMAN AF-Q86SG6-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 266 0 None None Serine/threonine-protein kinase Nek8
NEK NEK9 NEK9_HUMAN AF-Q8TD19-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 44 - 316 0 None None Serine/threonine-protein kinase Nek9
NEK NEK9 NEK9_HUMAN AF-Q8TD19-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 44 - 316 0 None None Serine/threonine-protein kinase Nek9

NEK / All / All

Total number of chains: 90
Active chains: 22
Total number of genes: 11
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 25 27.8% 9NFQC
DFGin BLAminus 23 25.6% AF-Q96PY6-K1A
None None 20 22.2% 2W5AA
DFGout None 13 14.4% 8SXNA
DFGinter BABtrans 4 4.4% 4B9DB
DFGinter None 2 2.2% 2W5BA
DFGout BBAminus 2 2.2% 8WS0B
DFGin BLBminus 1 1.1% 5M53A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
NEK NEK1 NEK1_HUMAN AF-Q96PY6-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 266 0 None None Serine/threonine-protein kinase Nek1 Homo sapiens
NEK NEK1 NEK1_HUMAN AF-Q96PY6-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 266 0 None None Serine/threonine-protein kinase Nek1 Homo sapiens
NEK NEK1 NEK1_HUMAN 4APCA 2.1 Inactive DFGinter‑BABtrans out-none out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 1 - 284 0 None T162A Serine/threonine-protein kinase Nek1 Homo sapiens
NEK NEK1 NEK1_HUMAN 4APCB 2.1 Inactive DFGinter‑BABtrans out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 1 - 284 0 None T162A Serine/threonine-protein kinase Nek1 Homo sapiens
NEK NEK1 NEK1_HUMAN 4B9DA 1.9 Inactive DFGinter‑BABtrans out-none out-out nonTYR APEdihe_aaiii APEdist_oooo CK7 Type1 1 - 284 0 None T162A Serine/threonine-protein kinase Nek1 Homo sapiens
NEK NEK1 NEK1_HUMAN 4B9DB 1.9 Inactive DFGinter‑BABtrans out-out out-out nonTYR APEdihe_aaiii APEdist_oooo CK7 Type1 1 - 284 0 None T162A Serine/threonine-protein kinase Nek1 Homo sapiens
NEK NEK10 NEK10_HUMAN AF-Q6ZWH5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 511 - 793 0 None None Serine/threonine-protein kinase Nek10 Homo sapiens
NEK NEK10 NEK10_HUMAN AF-Q6ZWH5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 511 - 793 0 None None Serine/threonine-protein kinase Nek10 Homo sapiens
NEK NEK11 NEK11_HUMAN AF-Q8NG66-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 21 - 295 0 None None Serine/threonine-protein kinase Nek11 Homo sapiens
NEK NEK11 NEK11_HUMAN AF-Q8NG66-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 21 - 295 0 None None Serine/threonine-protein kinase Nek11 Homo sapiens
NEK NEK2 NEK2_HUMAN AF-P51955-K1A -1.0 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 279 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN AF-P51955-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 279 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 5M53A 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 7GJ Type1 7 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2XKDA 1.96 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnnn T3M Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2XKEA 2.203 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanio APEdist_nnnn WI2 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2XKFA 2.35 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnno BX1 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 5M51A 1.899 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaioo APEdist_nnno NU6 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 5M57A 2.3 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaioo APEdist_nnno 4SP Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2W5BA 2.4 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiio APEdist_oooo AGS ATPlike 3 - 271 0 None T175A Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2W5HA 2.33 Inactive DFGinter‑None out-none none-out nonTYR APEdihe_aaiio APEdist_iooo No_ligand No_ligand 3 - 271 0 None T175A Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2XK3A 2.2 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno XK3 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2XK4A 2.1 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nooo OL2 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2XK8A 2.001 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno 5R1 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2XNPA 1.98 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nooo WCX Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 4AFEA 2.597 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnoo GGY Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 4A4XA 2.4 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnoo JUP Type1 3 - 271 0 None T170E,S171D,T175E Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2W5AA 1.55 Inactive None‑None out-out out-out nonTYR APEdihe_aaiio APEdist_oooo ADP ATPlike 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2WQOA 2.167 Inactive None‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnnn VGK Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2XK6A 2.2 Inactive None‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno EQH Type1 4 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2XK7A 1.992 Inactive None‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno 30E Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2XKCA 2.5 Inactive None‑None out-none none-out nonTYR APEdihe_aaiio APEdist_nnnn 4VQ Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2XNMA 1.85 Inactive None‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nooo WGZ Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2XNNA 2.5 Inactive None‑None out-none none-out nonTYR APEdihe_aaioo APEdist_nnno 430 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2XNOA 1.98 Inactive None‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno ED8 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 5M55A 2.4 Inactive None‑None out-none none-out nonTYR APEdihe_aanoo APEdist_nnnn 7GG Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 6SGDA 2.0 Inactive None‑None out-none none-out nonTYR APEdihe_aaiio APEdist_nnnn LD5 Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 6SGHA 3.0 Inactive None‑None out-none none-none nonTYR APEdihe_aannn APEdist_nnnn LCW Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 6SGIA 2.3 Inactive None‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno LCB Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 6SGKA 2.0 Inactive None‑None out-none none-out nonTYR APEdihe_aaiio APEdist_nnnn LCQ Type1 3 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 6SK9A 2.0 Inactive None‑None out-none none-out nonTYR APEdihe_aaioo APEdist_nnnn F9N Type1 4 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK2 NEK2_HUMAN 2JAVA 2.2 Inactive None‑None out-out none-out nonTYR APEdihe_aaooo APEdist_nnnn 5Z5 Type1 3 - 271 0 None T175A Serine/threonine-protein kinase Nek2 Homo sapiens
NEK NEK3 NEK3_HUMAN AF-P51956-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 265 0 None None Serine/threonine-protein kinase Nek3 Homo sapiens
NEK NEK3 NEK3_HUMAN AF-P51956-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 265 0 None None Serine/threonine-protein kinase Nek3 Homo sapiens
NEK NEK4 NEK4_HUMAN AF-P51957-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 269 0 None None Serine/threonine-protein kinase Nek4 Homo sapiens
NEK NEK4 NEK4_HUMAN AF-P51957-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 269 0 None None Serine/threonine-protein kinase Nek4 Homo sapiens
NEK NEK5 NEK5_HUMAN AF-Q6P3R8-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 267 0 None None Serine/threonine-protein kinase Nek5 Homo sapiens
NEK NEK5 NEK5_HUMAN AF-Q6P3R8-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 267 0 None None Serine/threonine-protein kinase Nek5 Homo sapiens
NEK NEK6 NEK6_HUMAN AF-Q9HC98-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 37 - 313 0 None None Serine/threonine-protein kinase Nek6 Homo sapiens
NEK NEK6 NEK6_HUMAN AF-Q9HC98-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 37 - 313 0 None None Serine/threonine-protein kinase Nek6 Homo sapiens
NEK NEK7 NEK7_HUMAN AF-Q8TDX7-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 302 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN AF-Q8TDX7-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 302 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 9H59C 3.4 Inactive DFGin‑BLAminus out-out out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 23 - 302 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 9NFQC 3.25 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioo APEdist_oooo ADP ATPlike 20 - 300 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 2WQNA 2.3 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanno APEdist_nnnn ADP ATPlike 21 - 300 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8EJ4K 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8EJ4L 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8EJ4M 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8EJ4N 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8EJ4O 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8EJ4P 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8EJ4Q 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8EJ4R 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8EJ4S 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8EJ4T 3.4 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 20 - 297 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 2WQMA 2.1 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 20 - 300 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 6S76B 3.38 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaino APEdist_nnoo No_ligand No_ligand 20 - 300 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 6S76C 3.38 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanoo APEdist_nnnn No_ligand No_ligand 20 - 300 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 6S73A 3.5 Inactive DFGin‑None out-none out-out nonTYR APEdihe_aaiio APEdist_nooo F9N Type1 21 - 300 0 None L86H,Y97F,L180F Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 6S73B 3.5 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnoo F9N Type1 20 - 300 0 None L86H,Y97F,L180F Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 6S73C 3.5 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn F9N Type1 26 - 300 0 None L86H,Y97F,L180F Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 6S75B 3.3 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaino APEdist_nnno F9N Type1 20 - 300 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 6S75C 3.3 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn F9N Type1 22 - 300 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8WS0B 2.12 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 19 - 299 0 None S195D Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8WS1B 2.4 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 20 - 300 0 None D161N Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 5DE2A 2.78 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaooo APEdist_nnno No_ligand No_ligand 20 - 300 0 None Y97F Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 6S75D 3.3 Inactive DFGout‑None out-none none-out nonTYR APEdihe_aanoo APEdist_nnnn No_ligand No_ligand 28 - 299 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8WS0A 2.12 Inactive DFGout‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 20 - 300 0 None S195D Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8SXNA 4.04 Inactive DFGout‑None out-na out-out nonTYR APEdihe_aaioo APEdist_oiio No_ligand No_ligand 19 - 302 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8SXNB 4.04 Inactive DFGout‑None out-na out-out nonTYR APEdihe_aaioo APEdist_oiio No_ligand No_ligand 19 - 302 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8WS1A 2.4 Inactive DFGout‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 20 - 300 0 None D161N Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 6S75A 3.3 Inactive DFGout‑None out-none none-out nonTYR APEdihe_aanio APEdist_nnnn F9N Type1 19 - 300 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 6NPYB 3.8 Inactive None‑None none-none none-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 113 - 300 0 None L54R,V58K,P59T,K87A,A99V,S100C,E103T,D104G Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 5DE2B 2.78 Inactive None‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 20 - 300 0 None Y97F Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 6S73D 3.5 Inactive None‑None out-none none-out nonTYR APEdihe_aanoo APEdist_nnnn No_ligand No_ligand 23 - 300 0 None L86H,Y97F,L180F Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 6S76A 3.38 Inactive None‑None out-none none-out nonTYR APEdihe_aaiio APEdist_nnno No_ligand No_ligand 21 - 300 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 6S76D 3.38 Inactive None‑None out-none none-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 25 - 300 0 None None Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK8 NEK8_HUMAN AF-Q86SG6-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 266 0 None None Serine/threonine-protein kinase Nek8 Homo sapiens
NEK NEK8 NEK8_HUMAN AF-Q86SG6-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 266 0 None None Serine/threonine-protein kinase Nek8 Homo sapiens
NEK NEK9 NEK9_HUMAN AF-Q8TD19-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 44 - 316 0 None None Serine/threonine-protein kinase Nek9 Homo sapiens
NEK NEK9 NEK9_HUMAN AF-Q8TD19-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 44 - 316 0 None None Serine/threonine-protein kinase Nek9 Homo sapiens

NEK / All / All

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism