TKL_ARAF (Serine/threonine-protein kinase A-Raf)

Total number of chains: 4
Active chains: 2
Uniprot: ARAF_HUMAN
Kinase Domain Residues: 310 - 569
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% AF-P10398-K1A
DFGin BLBplus 1 25.0% 9AXMB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P10398-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 302 - 577 0 None None Serine/threonine-protein kinase A-Raf
AF-P10398-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 302 - 577 0 None None Serine/threonine-protein kinase A-Raf
9AXMD 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 300 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf
9AXMB 2.42 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnni ANP ATPlike 302 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf

TKL_ARAF (Serine/threonine-protein kinase A-Raf)

Total number of chains: 4
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% AF-P10398-K1A
DFGin BLBplus 1 25.0% 9AXMB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
ARAF_HUMAN AF-P10398-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 302 - 577 0 None None Serine/threonine-protein kinase A-Raf Homo sapiens
ARAF_HUMAN AF-P10398-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 302 - 577 0 None None Serine/threonine-protein kinase A-Raf Homo sapiens
ARAF_HUMAN 9AXMD 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 300 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf Homo sapiens
ARAF_HUMAN 9AXMB 2.42 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaioi APEdist_nnni ANP ATPlike 302 - 574 0 None Y301D,Y302D Serine/threonine-protein kinase A-Raf Homo sapiens

TKL_ARAF (Serine/threonine-protein kinase A-Raf)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism