CMGC_SRPK1 (SRSF protein kinase 1)

Total number of chains: 17
Active chains: 9
Uniprot: SRPK1_HUMAN
Kinase Domain Residues: 80 - 653
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 16 94.1% AF-Q96SB4-K1A
DFGin ABAminus 1 5.9% 5MY8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
1WBPA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 67 - 655 0 None None SRSF protein kinase 1
AF-Q96SB4-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 72 - 655 0 None None SRSF protein kinase 1
AF-Q96SB4-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 72 - 655 0 None None SRSF protein kinase 1
7PQSA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 80H Type1 66 - 655 0 None None SRSF protein kinase 1
7PQSB 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 80H Type1 66 - 655 0 None None SRSF protein kinase 1
7ZKSA 2.28 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXQ Type1 67 - 655 0 None None SRSF protein kinase 1
4WUAA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3UL Type1 69 - 655 0 None None SRSF protein kinase 1
5XV7A 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EMH Type1 67 - 655 0 None None SRSF protein kinase 1
5MXXA 1.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 56 - 655 0 None None SRSF protein kinase 1
5MY8A 1.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RXZ Type1 64 - 655 0 None None SRSF protein kinase 1
3BEGA 2.9 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 69 - 655 0 None None SRSF protein kinase 1
1WAKA 1.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 63 - 655 0 None None SRSF protein kinase 1
7DD1A 2.05 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 67 - 655 0 None None SRSF protein kinase 1
6FADA 2.801 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 55 - 655 0 None None SRSF protein kinase 1
6FADB 2.801 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 55 - 655 0 None None SRSF protein kinase 1
6FADC 2.801 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 55 - 655 0 None None SRSF protein kinase 1
6FADD 2.801 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 55 - 655 0 None None SRSF protein kinase 1

CMGC_SRPK1 (SRSF protein kinase 1)

Total number of chains: 17
Active chains: 9
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 16 94.1% AF-Q96SB4-K1A
DFGin ABAminus 1 5.9% 5MY8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
SRPK1_HUMAN 1WBPA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 67 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN AF-Q96SB4-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 72 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN AF-Q96SB4-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 72 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN 7PQSA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 80H Type1 66 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN 7PQSB 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 80H Type1 66 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN 7ZKSA 2.28 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXQ Type1 67 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN 4WUAA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3UL Type1 69 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN 5XV7A 2.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EMH Type1 67 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN 5MXXA 1.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 56 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN 5MY8A 1.7 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RXZ Type1 64 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN 3BEGA 2.9 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 69 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN 1WAKA 1.73 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 63 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN 7DD1A 2.05 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 67 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN 6FADA 2.801 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 55 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN 6FADB 2.801 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 55 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN 6FADC 2.801 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 55 - 655 0 None None SRSF protein kinase 1 Homo sapiens
SRPK1_HUMAN 6FADD 2.801 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 55 - 655 0 None None SRSF protein kinase 1 Homo sapiens

CMGC_SRPK1 (SRSF protein kinase 1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism