SRPK1 (SRSF protein kinase 1)

Group: CMGC

Uniprot: SRPK1_HUMAN

Domain boundary: 80 - 653

Total number of chains: 16

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	15	AF-Q96SB4-K1A
DFGin	ABAminus	1	5MY8A

Database table as tsv

PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
5MY8A	1.7	Inactive	DFGin	ABAminus	in-in	in-in	RXZ	Type1	64 - 655	None	None	0
1WAKA	1.73	Inactive	DFGin	BLAminus	in-out	in-in	No_ligand	No_ligand	63 - 655	None	None	0
7DD1A	2.05	Inactive	DFGin	BLAminus	in-out	in-in	No_ligand	No_ligand	67 - 655	None	None	0
AF-Q96SB4-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	72 - 655	None	None	0
6FADA	2.801	Inactive	DFGin	BLAminus	in-out	in-in	No_ligand	No_ligand	55 - 655	None	None	0
6FADB	2.801	Inactive	DFGin	BLAminus	in-out	in-in	No_ligand	No_ligand	55 - 655	None	None	0
6FADC	2.801	Inactive	DFGin	BLAminus	in-out	in-in	No_ligand	No_ligand	55 - 655	None	None	0
6FADD	2.801	Inactive	DFGin	BLAminus	out-out	in-in	No_ligand	No_ligand	55 - 655	None	None	0
3BEGA	2.9	None	DFGin	BLAminus	in-none	in-in	ANP	Type1	69 - 655	None	None	0
7PQSA	2.2	Active	DFGin	BLAminus	in-in	in-in	80H	Type1	66 - 655	None	None	0
7PQSB	2.2	Active	DFGin	BLAminus	in-in	in-in	80H	Type1	66 - 655	None	None	0
7ZKSA	2.28	Active	DFGin	BLAminus	in-in	in-in	IXQ	Type1	67 - 655	None	None	0
1WBPA	2.4	Active	DFGin	BLAminus	in-in	in-in	ADP	Type1	67 - 655	None	None	0
4WUAA	2.0	Active	DFGin	BLAminus	in-in	in-in	3UL	Type1	69 - 655	None	None	0
5XV7A	2.32	Active	DFGin	BLAminus	in-in	in-in	EMH	Type1	67 - 655	None	None	0
5MXXA	1.75	Active	DFGin	BLAminus	in-in	in-in	W4A	Type1	56 - 655	None	None	0

SRPK1 (SRSF protein kinase 1)

Group: CMGC

Total number of chains: 16

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	15	AF-Q96SB4-K1A
DFGin	ABAminus	1	5MY8A

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Homo sapiens	SRPK1_HUMAN	5MY8A	1.7	Inactive	DFGin	ABAminus	in-in	in-in	RXZ	Type1	64 - 655	None	None	0
Homo sapiens	SRPK1_HUMAN	1WAKA	1.73	Inactive	DFGin	BLAminus	in-out	in-in	No_ligand	No_ligand	63 - 655	None	None	0
Homo sapiens	SRPK1_HUMAN	7DD1A	2.05	Inactive	DFGin	BLAminus	in-out	in-in	No_ligand	No_ligand	67 - 655	None	None	0
Homo sapiens	SRPK1_HUMAN	AF-Q96SB4-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	72 - 655	None	None	0
Homo sapiens	SRPK1_HUMAN	6FADA	2.801	Inactive	DFGin	BLAminus	in-out	in-in	No_ligand	No_ligand	55 - 655	None	None	0
Homo sapiens	SRPK1_HUMAN	6FADB	2.801	Inactive	DFGin	BLAminus	in-out	in-in	No_ligand	No_ligand	55 - 655	None	None	0
Homo sapiens	SRPK1_HUMAN	6FADC	2.801	Inactive	DFGin	BLAminus	in-out	in-in	No_ligand	No_ligand	55 - 655	None	None	0
Homo sapiens	SRPK1_HUMAN	6FADD	2.801	Inactive	DFGin	BLAminus	out-out	in-in	No_ligand	No_ligand	55 - 655	None	None	0
Homo sapiens	SRPK1_HUMAN	3BEGA	2.9	None	DFGin	BLAminus	in-none	in-in	ANP	Type1	69 - 655	None	None	0
Homo sapiens	SRPK1_HUMAN	7PQSA	2.2	Active	DFGin	BLAminus	in-in	in-in	80H	Type1	66 - 655	None	None	0
Homo sapiens	SRPK1_HUMAN	7PQSB	2.2	Active	DFGin	BLAminus	in-in	in-in	80H	Type1	66 - 655	None	None	0
Homo sapiens	SRPK1_HUMAN	7ZKSA	2.28	Active	DFGin	BLAminus	in-in	in-in	IXQ	Type1	67 - 655	None	None	0
Homo sapiens	SRPK1_HUMAN	1WBPA	2.4	Active	DFGin	BLAminus	in-in	in-in	ADP	Type1	67 - 655	None	None	0
Homo sapiens	SRPK1_HUMAN	4WUAA	2.0	Active	DFGin	BLAminus	in-in	in-in	3UL	Type1	69 - 655	None	None	0
Homo sapiens	SRPK1_HUMAN	5XV7A	2.32	Active	DFGin	BLAminus	in-in	in-in	EMH	Type1	67 - 655	None	None	0
Homo sapiens	SRPK1_HUMAN	5MXXA	1.75	Active	DFGin	BLAminus	in-in	in-in	W4A	Type1	56 - 655	None	None	0

SRPK1 (SRSF protein kinase 1)

No non-human structures known.