All / Activity_Active / ATPlike

Total number of chains: 178
Active chains: 178
Total number of genes: 55
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 178 100.0% 8QCGB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC AKT1 AKT1_HUMAN 4EKKA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 144 - 477 0 TPO308 S473D RAC-alpha serine/threonine-protein kinase
AGC AKT1 AKT1_HUMAN 4EKKB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 144 - 477 0 TPO308 S473D RAC-alpha serine/threonine-protein kinase
AGC AKT2 AKT2_HUMAN 1O6KA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 146 - 479 0 TPO309 S474D RAC-beta serine/threonine-protein kinase
AGC AKT2 AKT2_HUMAN 1O6LA 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 146 - 477 0 TPO309 None RAC-beta serine/threonine-protein kinase
AGC CDC42BPB MRCKB_HUMAN 4UAKA 1.73 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 417 0 None None Serine/threonine-protein kinase MRCK beta
AGC GRK4 GRK4_HUMAN 4YHJA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 25 - 525 0 None C563S,C578S G protein-coupled receptor kinase 4
AGC GRK4 GRK4_HUMAN 4YHJB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 25 - 527 0 None C563S,C578S G protein-coupled receptor kinase 4
AGC GRK5 GRK5_HUMAN 4TNDA 1.802 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 543 0 None None G protein-coupled receptor kinase 5
AGC GRK5 GRK5_HUMAN 9CKRA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 25 - 542 0 None D311N G protein-coupled receptor kinase 5
AGC GRK5 GRK5_HUMAN 9CKSA 3.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 25 - 542 0 None D311N G protein-coupled receptor kinase 5
AGC GRK6 GRK6_HUMAN 2ACXA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 532 0 None C561S,C562S,C565S G protein-coupled receptor kinase 6
AGC GRK6 GRK6_HUMAN 2ACXB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 535 0 None C561S,C562S,C565S G protein-coupled receptor kinase 6
AGC GRK6 GRK6_HUMAN 3NYOA 2.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 2 - 557 0 None None G protein-coupled receptor kinase 6
AGC GRK6 GRK6_HUMAN 3NYOB 2.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 2 - 557 0 None None G protein-coupled receptor kinase 6
AGC PDPK1 PDPK1_HUMAN 2BIYA 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 72 - 359 0 None S241A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 3HRCA 1.91 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 76 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 4RRVA 1.412 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 76 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 5ACKA 1.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 73 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 5LVPA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 75 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 5LVPB 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 74 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 5LVPC 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 75 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 5LVPD 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 74 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 4CT2A 1.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 75 - 359 0 SEP241 L113V,I118V,I119H,V124I,T128Q,R131K,T148C,F157L,Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 5MRDA 1.41 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 76 - 359 0 SEP241 K76S,L113V,I118V,I119N,V124I,T128Q,R131K,T148C 3-phosphoinositide-dependent protein kinase 1
AGC PRKACA KAPCA_HUMAN 4WB8A 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4WB5A 1.641 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4WB7A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4WB7B 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 6BYRA 3.661 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 6BYRC 3.661 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 9EDCA 4.18 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4WB6A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 14 - 351 0 SEP11,SEP140,TPO198 L206R cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4WB6B 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 9 - 351 0 SEP11,TPO198,SEP339 L206R cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKCB KPCB_HUMAN 8SE1A 3.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 19 - 668 0 TPO500,TPO642,SEP661 None Protein kinase C beta type
AGC PRKCB KPCB_HUMAN 8SE1B 3.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 19 - 668 0 TPO500,TPO642,SEP661 None Protein kinase C beta type
AGC PRKCB KPCB_HUMAN 8SE2B 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 30 - 671 0 TPO500,TPO642,SEP661 None Protein kinase C beta type
AGC PRKCI KPCI_HUMAN 5LIHA 3.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 248 - 588 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 5LIHB 3.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 249 - 588 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 5LI9A 1.79 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 248 - 589 0 TPO412,TPO564 None Protein kinase C iota type
AGC PRKCI KPCI_HUMAN 5LI1A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 248 - 589 0 TPO412,SEP484,TPO564 None Protein kinase C iota type
AGC PRKG1 KGP1_HUMAN 6BG2A 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 336 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 6BG2B 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 346 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 6BG2C 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 337 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 6BG2D 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 344 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 7LV3A 2.41 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 57 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC PRKG1 KGP1_HUMAN 7LV3B 2.41 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 58 - 671 0 TPO517 None cGMP-dependent protein kinase 1
AGC ROCK1 ROCK1_HUMAN 2V55A 3.705 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 6 - 404 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 2V55C 3.705 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 6 - 404 0 None None Rho-associated protein kinase 1
CAMK AURKA AURKA_HUMAN 1OL5A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 123 - 388 0 TPO287,TPO288 None Aurora kinase A
CAMK AURKA AURKA_HUMAN 6VPGA 2.64 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 389 0 TPO287,TPO288 None Aurora kinase A
CAMK AURKA AURKA_HUMAN 5LXMA 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 126 - 392 0 TPO288 C290A,C393A Aurora kinase A
CAMK AURKA AURKA_HUMAN 5G1XA 1.72 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 126 - 389 0 TPO288 C290A,C393A Aurora kinase A
CAMK CAMK2A KCC2A_HUMAN 7UJSA 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 274 0 None Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha
CAMK CAMK2A KCC2A_HUMAN 7UIRA 3.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 274 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha
CAMK CAMK2A KCC2A_HUMAN 7UIRB 3.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 273 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha
CAMK CAMK2A KCC2A_HUMAN 7UJPA 2.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 274 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha
CAMK CAMK2A KCC2A_HUMAN 7UJPB 2.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 273 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha
CAMK CHEK1 CHK1_HUMAN 7AKMA 1.93 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 2 - 271 0 None D10R Serine/threonine-protein kinase Chk1
CAMK DAPK1 DAPK1_HUMAN 2W4KA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 302 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 2XUUA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 302 0 None E182A Death-associated protein kinase 1
CAMK DCLK1 DCLK1_HUMAN 5JZJA 1.71 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 374 - 648 0 None None Serine/threonine-protein kinase DCLK1
CAMK DCLK1 DCLK1_HUMAN 5JZJB 1.71 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 382 - 648 0 None None Serine/threonine-protein kinase DCLK1
CAMK PASK PASK_HUMAN 3DLSA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1266 0 None None PAS domain-containing serine/threonine-protein kinase
CAMK PASK PASK_HUMAN 3DLSB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1267 0 None None PAS domain-containing serine/threonine-protein kinase
CAMK PASK PASK_HUMAN 3DLSC 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1267 0 None None PAS domain-containing serine/threonine-protein kinase
CAMK PASK PASK_HUMAN 3DLSD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1266 0 None None PAS domain-containing serine/threonine-protein kinase
CAMK PASK PASK_HUMAN 3DLSE 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1267 0 None None PAS domain-containing serine/threonine-protein kinase
CAMK PASK PASK_HUMAN 3DLSF 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1266 0 None None PAS domain-containing serine/threonine-protein kinase
CAMK PIM1 PIM1_HUMAN 1YXTA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 33 - 306 0 None None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 1YXUA 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 1YXUB 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 1YXUC 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 34 - 305 0 None None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 1YXUD 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 1XR1A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 32 - 308 0 None None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 3A99A 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 2BZKB 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 33 - 305 0 None R250G Serine/threonine-protein kinase pim-1
CAMK STK11 STK11_HUMAN 2WTKC 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 47 - 342 0 None D194A Serine/threonine-protein kinase STK11
CAMK STK11 STK11_HUMAN 2WTKF 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 45 - 340 0 None D194A Serine/threonine-protein kinase STK11
CK1 CSNK1D KC1D_HUMAN 6RU6A 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 3 - 294 0 None None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 7P7FA 1.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 TPO220 None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 7P7FB 1.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 TPO220 None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 7P7HA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 None None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 7P7HB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 None None Casein kinase I isoform delta
CK1 TTBK1 TTBK1_HUMAN 4BTJA 2.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 21 - 312 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 4BTJB 2.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 21 - 313 0 None None Tau-tubulin kinase 1
CK1 TTBK2 TTBK2_HUMAN 6VRFA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 9 - 298 0 None None Tau-tubulin kinase 2
CK1 TTBK2 TTBK2_HUMAN 6VRFB 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 9 - 298 0 None None Tau-tubulin kinase 2
CMGC CDK2 CDK2_HUMAN 4I3ZA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4I3ZC 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QHRA 2.17 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QHRC 2.17 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QHWA 1.91 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QHWC 1.91 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1JSTA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 298 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1JSTC 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 298 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2CJMA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 292 0 PTR15,TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2CJMC 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 297 0 PTR15,TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4II5A 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4II5C 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1GY3A 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1GY3C 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1QMZA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1QMZC 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2CCHA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2CCHC 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2CCIA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2CCIC 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK7 CDK7_HUMAN 9HIYJ 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 310 0 None D97N Cyclin-dependent kinase 7
CMGC CDK9 CDK9_HUMAN 3BLQA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 325 0 TPO186 None Cyclin-dependent kinase 9
CMGC CDK9 CDK9_HUMAN 4IMYC 2.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 8 - 330 0 TPO186 None Cyclin-dependent kinase 9
CMGC CDK9 CDK9_HUMAN 4IMYE 2.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 8 - 330 0 TPO186 None Cyclin-dependent kinase 9
CMGC CDK9 CDK9_HUMAN 3MIAA 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 340 0 TPO186 None Cyclin-dependent kinase 9
CMGC CSNK2A1 CSK21_HUMAN 3JUHA 1.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 335 0 None V66A,M163L Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 3JUHB 1.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 335 0 None V66A,M163L Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 6Z19B 1.47 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 329 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 3NSZA 1.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 328 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 1PJKA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 332 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 2PVRA 1.605 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 329 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 3U87B 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 331 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5OQUB 2.324 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 4 - 327 0 None R21S Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5ORKB 2.143 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 4 - 326 0 None R21S Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 7QUXA 1.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 329 0 SEP2 None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 6YZHA 1.19 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 3 - 329 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5CU6A 1.36 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 3 - 329 0 None R21S,K74A,K75A,K76A Casein kinase II subunit alpha
CMGC CSNK2A2 CSK22_HUMAN 8QCGB 1.04 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 333 0 None C336S Casein kinase II subunit alpha'
CMGC DYRK1A DYR1A_HUMAN 7A4OA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC GSK3B GSK3B_HUMAN 4NM5A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 24 - 383 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 4NM7A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 25 - 383 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 4NM3A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 6 - 383 0 SEP9 None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 1J1BA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 388 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 1J1BB 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 23 - 386 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 1J1CA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 35 - 388 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 1J1CB 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 23 - 386 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 8XN6A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 384 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 1PYXA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 386 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 1PYXB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 383 0 None None Glycogen synthase kinase-3 beta
CMGC MAPK1 MK01_HUMAN 6OPGA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 10 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 5V60A 2.18 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 10 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1
CMGC MAPK12 MK12_HUMAN 1CM8A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 353 0 TPO183,PTR185 None Mitogen-activated protein kinase 12
CMGC MAPK12 MK12_HUMAN 1CM8B 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 353 0 TPO183,PTR185 None Mitogen-activated protein kinase 12
CMGC SRPK1 SRPK1_HUMAN 1WBPA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 67 - 655 0 None None SRSF protein kinase 1
OTHER HASPIN HASP_HUMAN 3DLZA 1.85 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa AMP ATPlike 470 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER TP53RK PRPK_HUMAN 6WQXC 2.53 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 17 - 247 0 None None EKC/KEOPS complex subunit TP53RK
OTHER TP53RK PRPK_HUMAN 6WQXD 2.53 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 18 - 247 0 None None EKC/KEOPS complex subunit TP53RK
OTHER WNK3 WNK3_HUMAN 5O26A 2.379 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 135 - 414 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 5O26B 2.379 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 136 - 413 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3
STE PAK3 PAK3_HUMAN 6FD3A 1.52 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 261 - 556 0 None A537D Serine/threonine-protein kinase PAK 3
STE PAK4 PAK4_HUMAN 4FIFA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 296 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 4FIFB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 297 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 4JDIA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 5UPKB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 588 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 7S46A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 589 0 None D440N,S474E Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 7S47A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 589 0 None D440N,S474E Serine/threonine-protein kinase PAK 4
STE STK24 STK24_HUMAN 3A7JA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 25 - 311 0 TPO190 None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 4QMLA 1.882 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 30 - 310 0 TPO190 None Serine/threonine-protein kinase 24
STE TAOK3 TAOK3_HUMAN 6BDNA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 8 - 314 0 None R2A,K3A Serine/threonine-protein kinase TAO3
STE TNIK TNIK_HUMAN 7XZRB 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 12 - 312 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase
TKL BMPR2 BMPR2_HUMAN 3G2FA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 510 0 None None Bone morphogenetic protein receptor type-2
TKL BMPR2 BMPR2_HUMAN 3G2FB 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 198 - 513 0 None None Bone morphogenetic protein receptor type-2
TKL BMPR2 BMPR2_HUMAN 6UNPB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 509 0 None D485G Bone morphogenetic protein receptor type-2
TKL IRAK4 IRAK4_HUMAN 2OIDD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL LIMK1 LIMK1_HUMAN 5L6WL 2.53 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 330 - 633 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 5HVKA 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 634 0 TPO508 D460N LIM domain kinase 1
TKL LRRK2 LRRK2_HUMAN 8FO9A 3.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8FO9C 3.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL TGFBR2 TGFR2_HUMAN 5E92A 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 240 - 543 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2
TYR EGFR EGFR_HUMAN 2ITXA 2.98 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 697 - 1019 0 None None Epidermal growth factor receptor
TYR FGFR1 FGFR1_HUMAN 3GQIA 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 464 - 770 0 PTR653,PTR654,PTR766 C488A,Y583F,C584S,Y585F Fibroblast growth factor receptor 1
TYR FGFR2 FGFR2_HUMAN 2PVFA 1.8 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 467 - 765 0 PTR586,PTR656,PTR657 C491A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 3CLYA 2.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 468 - 772 0 PTR656,PTR657 C491A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5EG3A 2.606 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 466 - 774 0 PTR769 Y466F,C491A,E565A,Y586L,Y588P,Y656F,Y657F,K659E Fibroblast growth factor receptor 2
TYR FGFR3 FGFR3_HUMAN 4K33A 2.341 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 459 - 755 0 None C482A,C582S,K650E Fibroblast growth factor receptor 3
TYR INSR INSR_HUMAN 3BU5A 2.1 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ATP ATPlike 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor
TYR INSR INSR_HUMAN 4XLVA 2.3 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 1001 - 1310 0 PTR999,PTR1185,PTR1189,PTR1190 Y992F,C1008S Insulin receptor
TYR JAK1-2 JAK1_HUMAN 6C7YA 2.499 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 869 - 1153 0 PTR1035 None Tyrosine-protein kinase JAK1
TYR LCK LCK_HUMAN 1QPCA 1.6 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 231 - 502 0 PTR394 None Tyrosine-protein kinase Lck
TYR SYK KSYK_HUMAN 4FL1A 1.79 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR TNK2 ACK1_HUMAN 1U54B 2.8 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 117 - 388 0 None None Activated CDC42 kinase 1

All / Activity_Active / ATPlike

Total number of chains: 310
Active chains: 310
Total number of genes: 79
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 310 100.0% 8QCGB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CKA1 CSK21_ARATH 6XX7A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 77 - 406 0 None None Casein kinase II subunit alpha-1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPBA 1.98 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPVA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPYA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPZA 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 866 - 1160 0 TPO1039,SEP1042,SEP1044 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4OH4A 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 863 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4OH4B 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4Q5JA 2.772 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 863 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4Q5JB 2.772 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
AGC GRK1 GRK1_BOVIN 3T8OA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 30 - 532 0 None L166K Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4WA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 31 - 533 0 TPO8 None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4WB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 5 - 533 0 TPO8 None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4XA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 30 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4XB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4ZA 1.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C50A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 30 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C50B 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 30 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C51A 3.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C51B 3.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9A 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9B 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9C 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9D 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC PRKACA KAPCA_BOVIN 9DW9G 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 1Q24A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 15 - 351 0 TPO198,SEP339 V124A,L174M cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
CMGC CKA1 A0A1D8PUA2_CANAL 6O6QA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 4 - 333 0 None None Casein kinase II subunit alpha Candida albicans
CMGC CKA1 A0A1D8PUA2_CANAL 6O6QB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 5 - 333 0 None None Casein kinase II subunit alpha Candida albicans
AGC PRKACA KAPCA_CRIGR 6EM7A 1.238 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 11 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6EMAA 1.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6ESAA 1.307 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 11 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6Y8CA 1.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
CMGC CK2 Q5KF69_CRYD1 6ISEA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 331 0 None None Casein kinase II subunit alpha Cryptococcus deneoformans
CMGC CK2 Q5KF69_CRYD1 6ISEB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 331 0 None None Casein kinase II subunit alpha Cryptococcus deneoformans
CMGC CKA1 J9VNH4_CRYN9 6KO6B 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 334 0 None None Casein kinase II subunit alpha Cryptococcus neoformans
OTHER PK1 A0A097P1P8_GVCP 6VVGA 2.01 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 279 0 None None PK-1 Cydia pomonella granulosis virus
OTHER PK1 A0A097P1P8_GVCP 6VVGB 2.01 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 278 0 None None PK-1 Cydia pomonella granulosis virus
CAMK CAMKII KCC2A_DROME 5FG8A 1.955 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 275 0 None None Calcium/calmodulin-dependent protein kinase type II alpha chain Drosophila melanogaster
CAMK CAMKII KCC2A_DROME 5H9BA 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 7 - 275 0 None None Calcium/calmodulin-dependent protein kinase type II alpha chain Drosophila melanogaster
CAMK CAMKII KCC2A_DROME 5HU3A 1.885 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 272 0 None D136N Calcium/calmodulin-dependent protein kinase type II alpha chain Drosophila melanogaster
CAMK CDPK Q3HNM4_EIMTE 4YSJA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 499 0 None None non-specific serine/threonine protein kinase Eimeria tenella
CAMK CDPK Q3HNM4_EIMTE 4YSJB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 499 0 None None non-specific serine/threonine protein kinase Eimeria tenella
TYR PTK2 FAK1_CHICK 6TY4A 5.96 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 34 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 6TY4B 5.96 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 34 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR SRC SRC_CHICK 3DQWA 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 255 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQWB 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 255 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQWC 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 258 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQWD 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 257 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQXB 2.3 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AMP ATPlike 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
AGC AKT1 AKT1_HUMAN 4EKKA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 144 - 477 0 TPO308 S473D RAC-alpha serine/threonine-protein kinase Homo sapiens
AGC AKT1 AKT1_HUMAN 4EKKB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 144 - 477 0 TPO308 S473D RAC-alpha serine/threonine-protein kinase Homo sapiens
AGC AKT2 AKT2_HUMAN 1O6KA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 146 - 479 0 TPO309 S474D RAC-beta serine/threonine-protein kinase Homo sapiens
AGC AKT2 AKT2_HUMAN 1O6LA 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 146 - 477 0 TPO309 None RAC-beta serine/threonine-protein kinase Homo sapiens
AGC CDC42BPB MRCKB_HUMAN 4UAKA 1.73 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 417 0 None None Serine/threonine-protein kinase MRCK beta Homo sapiens
AGC GRK4 GRK4_HUMAN 4YHJA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 25 - 525 0 None C563S,C578S G protein-coupled receptor kinase 4 Homo sapiens
AGC GRK4 GRK4_HUMAN 4YHJB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 25 - 527 0 None C563S,C578S G protein-coupled receptor kinase 4 Homo sapiens
AGC GRK5 GRK5_HUMAN 4TNDA 1.802 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 543 0 None None G protein-coupled receptor kinase 5 Homo sapiens
AGC GRK5 GRK5_HUMAN 9CKRA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 25 - 542 0 None D311N G protein-coupled receptor kinase 5 Homo sapiens
AGC GRK5 GRK5_HUMAN 9CKSA 3.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 25 - 542 0 None D311N G protein-coupled receptor kinase 5 Homo sapiens
AGC GRK6 GRK6_HUMAN 2ACXA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 532 0 None C561S,C562S,C565S G protein-coupled receptor kinase 6 Homo sapiens
AGC GRK6 GRK6_HUMAN 2ACXB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 535 0 None C561S,C562S,C565S G protein-coupled receptor kinase 6 Homo sapiens
AGC GRK6 GRK6_HUMAN 3NYOA 2.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 2 - 557 0 None None G protein-coupled receptor kinase 6 Homo sapiens
AGC GRK6 GRK6_HUMAN 3NYOB 2.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 2 - 557 0 None None G protein-coupled receptor kinase 6 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 2BIYA 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 72 - 359 0 None S241A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 3HRCA 1.91 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 76 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 4RRVA 1.412 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 76 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 5ACKA 1.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 73 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 5LVPA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 75 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 5LVPB 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 74 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 5LVPC 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 75 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 5LVPD 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 74 - 359 0 SEP241 Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 4CT2A 1.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 75 - 359 0 SEP241 L113V,I118V,I119H,V124I,T128Q,R131K,T148C,F157L,Y288G,Q292A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 5MRDA 1.41 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 76 - 359 0 SEP241 K76S,L113V,I118V,I119N,V124I,T128Q,R131K,T148C 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PRKACA KAPCA_HUMAN 4WB8A 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 4WB5A 1.641 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 4WB7A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 4WB7B 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 6BYRA 3.661 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 6BYRC 3.661 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 9EDCA 4.18 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 4WB6A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 14 - 351 0 SEP11,SEP140,TPO198 L206R cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKACA KAPCA_HUMAN 4WB6B 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 9 - 351 0 SEP11,TPO198,SEP339 L206R cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens
AGC PRKCB KPCB_HUMAN 8SE1A 3.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 19 - 668 0 TPO500,TPO642,SEP661 None Protein kinase C beta type Homo sapiens
AGC PRKCB KPCB_HUMAN 8SE1B 3.32 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 19 - 668 0 TPO500,TPO642,SEP661 None Protein kinase C beta type Homo sapiens
AGC PRKCB KPCB_HUMAN 8SE2B 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 30 - 671 0 TPO500,TPO642,SEP661 None Protein kinase C beta type Homo sapiens
AGC PRKCI KPCI_HUMAN 5LIHA 3.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 248 - 588 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 5LIHB 3.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 249 - 588 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 5LI9A 1.79 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 248 - 589 0 TPO412,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKCI KPCI_HUMAN 5LI1A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 248 - 589 0 TPO412,SEP484,TPO564 None Protein kinase C iota type Homo sapiens
AGC PRKG1 KGP1_HUMAN 6BG2A 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 336 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC PRKG1 KGP1_HUMAN 6BG2B 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 346 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC PRKG1 KGP1_HUMAN 6BG2C 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 337 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC PRKG1 KGP1_HUMAN 6BG2D 1.83 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 344 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC PRKG1 KGP1_HUMAN 7LV3A 2.41 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 57 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC PRKG1 KGP1_HUMAN 7LV3B 2.41 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 58 - 671 0 TPO517 None cGMP-dependent protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 2V55A 3.705 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 6 - 404 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 2V55C 3.705 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 6 - 404 0 None None Rho-associated protein kinase 1 Homo sapiens
CAMK AURKA AURKA_HUMAN 1OL5A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 123 - 388 0 TPO287,TPO288 None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 6VPGA 2.64 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 389 0 TPO287,TPO288 None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5LXMA 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 126 - 392 0 TPO288 C290A,C393A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5G1XA 1.72 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 126 - 389 0 TPO288 C290A,C393A Aurora kinase A Homo sapiens
CAMK CAMK2A KCC2A_HUMAN 7UJSA 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 274 0 None Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha Homo sapiens
CAMK CAMK2A KCC2A_HUMAN 7UIRA 3.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 274 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha Homo sapiens
CAMK CAMK2A KCC2A_HUMAN 7UIRB 3.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 273 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha Homo sapiens
CAMK CAMK2A KCC2A_HUMAN 7UJPA 2.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 274 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha Homo sapiens
CAMK CAMK2A KCC2A_HUMAN 7UJPB 2.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 273 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha Homo sapiens
CAMK CHEK1 CHK1_HUMAN 7AKMA 1.93 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 2 - 271 0 None D10R Serine/threonine-protein kinase Chk1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 2W4KA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 302 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 2XUUA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 302 0 None E182A Death-associated protein kinase 1 Homo sapiens
CAMK DCLK1 DCLK1_HUMAN 5JZJA 1.71 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 374 - 648 0 None None Serine/threonine-protein kinase DCLK1 Homo sapiens
CAMK DCLK1 DCLK1_HUMAN 5JZJB 1.71 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 382 - 648 0 None None Serine/threonine-protein kinase DCLK1 Homo sapiens
CAMK PASK PASK_HUMAN 3DLSA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1266 0 None None PAS domain-containing serine/threonine-protein kinase Homo sapiens
CAMK PASK PASK_HUMAN 3DLSB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1267 0 None None PAS domain-containing serine/threonine-protein kinase Homo sapiens
CAMK PASK PASK_HUMAN 3DLSC 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1267 0 None None PAS domain-containing serine/threonine-protein kinase Homo sapiens
CAMK PASK PASK_HUMAN 3DLSD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1266 0 None None PAS domain-containing serine/threonine-protein kinase Homo sapiens
CAMK PASK PASK_HUMAN 3DLSE 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1267 0 None None PAS domain-containing serine/threonine-protein kinase Homo sapiens
CAMK PASK PASK_HUMAN 3DLSF 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 982 - 1266 0 None None PAS domain-containing serine/threonine-protein kinase Homo sapiens
CAMK PIM1 PIM1_HUMAN 1YXTA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 33 - 306 0 None None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 1YXUA 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 1YXUB 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 1YXUC 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 34 - 305 0 None None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 1YXUD 2.24 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 1XR1A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 32 - 308 0 None None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 3A99A 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 33 - 305 0 None None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 2BZKB 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 33 - 305 0 None R250G Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK STK11 STK11_HUMAN 2WTKC 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 47 - 342 0 None D194A Serine/threonine-protein kinase STK11 Homo sapiens
CAMK STK11 STK11_HUMAN 2WTKF 2.65 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 45 - 340 0 None D194A Serine/threonine-protein kinase STK11 Homo sapiens
CK1 CSNK1D KC1D_HUMAN 6RU6A 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 3 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 7P7FA 1.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 TPO220 None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 7P7FB 1.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 TPO220 None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 7P7HA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 7P7HB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 4BTJA 2.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 21 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 4BTJB 2.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 21 - 313 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK2 TTBK2_HUMAN 6VRFA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 9 - 298 0 None None Tau-tubulin kinase 2 Homo sapiens
CK1 TTBK2 TTBK2_HUMAN 6VRFB 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 9 - 298 0 None None Tau-tubulin kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4I3ZA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4I3ZC 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QHRA 2.17 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QHRC 2.17 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QHWA 1.91 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QHWC 1.91 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1JSTA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 298 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1JSTC 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 298 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2CJMA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 292 0 PTR15,TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2CJMC 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 297 0 PTR15,TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4II5A 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4II5C 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1GY3A 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1GY3C 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1QMZA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1QMZC 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2CCHA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2CCHC 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2CCIA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2CCIC 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK7 CDK7_HUMAN 9HIYJ 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 10 - 310 0 None D97N Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK9 CDK9_HUMAN 3BLQA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 325 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CMGC CDK9 CDK9_HUMAN 4IMYC 2.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 8 - 330 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CMGC CDK9 CDK9_HUMAN 4IMYE 2.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 8 - 330 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CMGC CDK9 CDK9_HUMAN 3MIAA 3.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 340 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 3JUHA 1.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 335 0 None V66A,M163L Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 3JUHB 1.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 335 0 None V66A,M163L Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 6Z19B 1.47 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 329 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 3NSZA 1.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 328 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 1PJKA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 332 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 2PVRA 1.605 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 329 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 3U87B 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 331 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 5OQUB 2.324 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 4 - 327 0 None R21S Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 5ORKB 2.143 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 4 - 326 0 None R21S Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 7QUXA 1.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 329 0 SEP2 None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 6YZHA 1.19 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 3 - 329 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 5CU6A 1.36 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 3 - 329 0 None R21S,K74A,K75A,K76A Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A2 CSK22_HUMAN 8QCGB 1.04 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 7A4OA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 136 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC GSK3B GSK3B_HUMAN 4NM5A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 24 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 4NM7A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 25 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 4NM3A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 6 - 383 0 SEP9 None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 1J1BA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 388 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 1J1BB 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 23 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 1J1CA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 35 - 388 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 1J1CB 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 23 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 8XN6A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 1PYXA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 1PYXB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC MAPK1 MK01_HUMAN 6OPGA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 10 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK1 MK01_HUMAN 5V60A 2.18 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 10 - 358 0 TPO185,PTR187 None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK12 MK12_HUMAN 1CM8A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 353 0 TPO183,PTR185 None Mitogen-activated protein kinase 12 Homo sapiens
CMGC MAPK12 MK12_HUMAN 1CM8B 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 8 - 353 0 TPO183,PTR185 None Mitogen-activated protein kinase 12 Homo sapiens
CMGC SRPK1 SRPK1_HUMAN 1WBPA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 67 - 655 0 None None SRSF protein kinase 1 Homo sapiens
OTHER HASPIN HASP_HUMAN 3DLZA 1.85 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa AMP ATPlike 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER TP53RK PRPK_HUMAN 6WQXC 2.53 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 17 - 247 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER TP53RK PRPK_HUMAN 6WQXD 2.53 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 18 - 247 0 None None EKC/KEOPS complex subunit TP53RK Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O26A 2.379 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 135 - 414 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O26B 2.379 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 136 - 413 0 SEP304,SEP308 None Serine/threonine-protein kinase WNK3 Homo sapiens
STE PAK3 PAK3_HUMAN 6FD3A 1.52 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 261 - 556 0 None A537D Serine/threonine-protein kinase PAK 3 Homo sapiens
STE PAK4 PAK4_HUMAN 4FIFA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 296 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 4FIFB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 297 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 4JDIA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 5UPKB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 588 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 7S46A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 589 0 None D440N,S474E Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 7S47A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 300 - 589 0 None D440N,S474E Serine/threonine-protein kinase PAK 4 Homo sapiens
STE STK24 STK24_HUMAN 3A7JA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 25 - 311 0 TPO190 None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 4QMLA 1.882 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 30 - 310 0 TPO190 None Serine/threonine-protein kinase 24 Homo sapiens
STE TAOK3 TAOK3_HUMAN 6BDNA 1.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 8 - 314 0 None R2A,K3A Serine/threonine-protein kinase TAO3 Homo sapiens
STE TNIK TNIK_HUMAN 7XZRB 2.26 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 12 - 312 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase Homo sapiens
TKL BMPR2 BMPR2_HUMAN 3G2FA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 510 0 None None Bone morphogenetic protein receptor type-2 Homo sapiens
TKL BMPR2 BMPR2_HUMAN 3G2FB 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 198 - 513 0 None None Bone morphogenetic protein receptor type-2 Homo sapiens
TKL BMPR2 BMPR2_HUMAN 6UNPB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 197 - 509 0 None D485G Bone morphogenetic protein receptor type-2 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2OIDD 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 164 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 5L6WL 2.53 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii AGS ATPlike 330 - 633 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 5HVKA 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 329 - 634 0 TPO508 D460N LIM domain kinase 1 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO9A 3.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8FO9C 3.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 1329 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL TGFBR2 TGFR2_HUMAN 5E92A 2.08 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 240 - 543 0 None E431A,R433A,E485A,K488A,R493A,R495A TGF-beta receptor type-2 Homo sapiens
TYR EGFR EGFR_HUMAN 2ITXA 2.98 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 697 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3GQIA 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 464 - 770 0 PTR653,PTR654,PTR766 C488A,Y583F,C584S,Y585F Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 2PVFA 1.8 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 467 - 765 0 PTR586,PTR656,PTR657 C491A Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 3CLYA 2.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 468 - 772 0 PTR656,PTR657 C491A Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 5EG3A 2.606 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 466 - 774 0 PTR769 Y466F,C491A,E565A,Y586L,Y588P,Y656F,Y657F,K659E Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 4K33A 2.341 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 459 - 755 0 None C482A,C582S,K650E Fibroblast growth factor receptor 3 Homo sapiens
TYR INSR INSR_HUMAN 3BU5A 2.1 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ATP ATPlike 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor Homo sapiens
TYR INSR INSR_HUMAN 4XLVA 2.3 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 1001 - 1310 0 PTR999,PTR1185,PTR1189,PTR1190 Y992F,C1008S Insulin receptor Homo sapiens
TYR JAK1-2 JAK1_HUMAN 6C7YA 2.499 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 869 - 1153 0 PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR LCK LCK_HUMAN 1QPCA 1.6 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 231 - 502 0 PTR394 None Tyrosine-protein kinase Lck Homo sapiens
TYR SYK KSYK_HUMAN 4FL1A 1.79 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 363 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR TNK2 ACK1_HUMAN 1U54B 2.8 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 117 - 388 0 None None Activated CDC42 kinase 1 Homo sapiens
OTHER LPL0262 Q5WZW9_LEGPL 5CKWA 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 404 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
OTHER LPL0262 Q5WZW9_LEGPL 5CKWB 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 1 - 404 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
AGC PRKACA KAPCA_MOUSE 4O21A 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7E11A 3.43 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3PVBA 3.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 1BKXA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 13 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 1L3RE 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 2QCSA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3FJQE 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3IDBA 1.62 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3IDCA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DG0E 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 11 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH1A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH3A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH5A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH7A 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH8A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4HPTE 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4HPUE 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 5JR7A 3.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 5JR7C 3.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7UJXE 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7V0GE 1.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 17 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DFXE 1.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4X6RA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3X2UA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3X2VA 1.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 18 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3X2WA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IACA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IADA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAFA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAIA 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAKA 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAYA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAZA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IB0A 1.87 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IB1A 1.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IB3A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4XW4A 1.82 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4XW5A 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4XW6A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6E21A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7E0ZA 2.162 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DG3E 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 351 0 SEP140,TPO198 R337A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3FHIA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 TPO198,SEP339 C200A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3QAME 1.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 TPO198,SEP339 E209A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3QALE 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 TPO198,SEP339 R281A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
CAMK CAMK2A KCC2A_MOUSE 7B56B 1.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 307 0 None T305A,T306A Calcium/calmodulin-dependent protein kinase type II subunit alpha Mus musculus
CAMK CAMK2A KCC2A_MOUSE 7B57B 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 5 - 307 0 None T305A,T306A Calcium/calmodulin-dependent protein kinase type II subunit alpha Mus musculus
CAMK DAPK2 DAPK2_MOUSE 2YAAA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 311 0 None None Death-associated protein kinase 2 Mus musculus
CAMK DAPK2 DAPK2_MOUSE 2YABA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
CMGC GSK3B GSK3B_MOUSE 8VMFA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 27 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
CMGC GSK3B GSK3B_MOUSE 8VMGA 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
CMGC GSK3B GSK3B_MOUSE 8VMEA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
CMGC GSK3B GSK3B_MOUSE 4NU1A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 6 - 383 0 SEP9 None Glycogen synthase kinase-3 beta Mus musculus
CMGC MAPK14 MK14_MOUSE 5NZZE 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 4 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5NZZF 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 5 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Mus musculus
TYR LYN LYN_MOUSE 2ZV8A 2.7 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 239 - 501 0 None None Tyrosine-protein kinase Lyn Mus musculus
CAMK PHKG1 PHKG1_RABIT 2PHKA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 15 - 291 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Oryctolagus cuniculus
CAMK PHKG1 PHKG1_RABIT 1QL6A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 292 0 None E183S Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Oryctolagus cuniculus
CAMK PHKG1 PHKG1_RABIT 1PHKA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 292 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Oryctolagus cuniculus
OTHER PINK1 PINK1_PEDHC 8UYHA 2.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 115 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYHB 2.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 121 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYIA 3.13 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 120 - 572 0 SEP202,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYIB 3.13 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 122 - 574 0 SEP202,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
CAMK CDPK1 CDPK1_PLABA 3Q5IA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 38 - 518 0 None None Calcium-dependent protein kinase 1 Plasmodium berghei
CMGC PSTK1 Q8IL19_PLAF7 3LLTA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 535 - 875 0 None None Protein serine/threonine kinase-1 Plasmodium falciparum
STE TAOK2 TAOK2_RAT 1U5RA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 320 0 SEP181 None Serine/threonine-protein kinase TAO2 Rattus norvegicus
STE TAOK2 TAOK2_RAT 1U5RB 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 320 0 SEP181 None Serine/threonine-protein kinase TAO2 Rattus norvegicus
CMGC SKY1 SKY1_YEAST 1Q8YA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 144 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
CMGC SKY1 SKY1_YEAST 1Q97A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 144 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
CMGC SKY1 SKY1_YEAST 1Q99A 2.11 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 143 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
CMGC SKY1 SKY1_YEAST 1Q99B 2.11 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 142 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WW7A 1.669 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa AMP ATPlike 4 - 257 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WW9A 1.951 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ADP ATPlike 4 - 259 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
TKL NCGRLOCUS634 A0ACD6BAX3_9POAL 8HO6A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 305 0 TPO184,SEP187,TPO188 None ScRIPK kinase protein Saccharum hybrid cultivar
CK1 CKI1 CKI1_SCHPO 1CSNA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 6 - 298 0 None None Casein kinase I homolog 1 Schizosaccharomyces pombe
AGC PRKACA KAPCA_PIG 1CDKA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Sus scrofa
AGC PRKACA KAPCA_PIG 1CDKB 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Sus scrofa
CMGC TVAG125560 A2F9N1_TRIV3 9AV7A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 318 0 None None non-specific serine/threonine protein kinase Trichomonas vaginalis
CMGC ACK2 CSK2A_MAIZE 1DS5A 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1DS5B 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1DS5C 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1DS5D 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays

All / Activity_Active / ATPlike

Total number of chains: 132
Active chains: 132
Total number of genes: 27
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 132 100.0% 6EM7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CKA1 CSK21_ARATH 6XX7A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 77 - 406 0 None None Casein kinase II subunit alpha-1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPBA 1.98 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPVA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPYA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 5LPZA 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 866 - 1160 0 TPO1039,SEP1042,SEP1044 T872A Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4OH4A 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 863 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4OH4B 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4Q5JA 2.772 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 863 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
TKL BRI1 BRI1_ARATH 4Q5JB 2.772 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 867 - 1160 0 TPO1039,SEP1042,SEP1044,SEP1060 None Protein BRASSINOSTEROID INSENSITIVE 1 Arabidopsis thaliana
AGC GRK1 GRK1_BOVIN 3T8OA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 30 - 532 0 None L166K Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4WA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 31 - 533 0 TPO8 None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4WB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 5 - 533 0 TPO8 None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4XA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 30 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4XB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C4ZA 1.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C50A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 30 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C50B 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 30 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C51A 3.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3C51B 3.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None None Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9A 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9B 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9C 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC GRK1 GRK1_BOVIN 3QC9D 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 31 - 533 0 None T8C,N480C Rhodopsin kinase GRK1 Bos taurus
AGC PRKACA KAPCA_BOVIN 9DW9G 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 1Q24A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 15 - 351 0 TPO198,SEP339 V124A,L174M cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
CMGC CKA1 A0A1D8PUA2_CANAL 6O6QA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 4 - 333 0 None None Casein kinase II subunit alpha Candida albicans
CMGC CKA1 A0A1D8PUA2_CANAL 6O6QB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 5 - 333 0 None None Casein kinase II subunit alpha Candida albicans
AGC PRKACA KAPCA_CRIGR 6EM7A 1.238 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 11 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6EMAA 1.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6ESAA 1.307 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 11 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
AGC PRKACA KAPCA_CRIGR 6Y8CA 1.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Cricetulus griseus
CMGC CK2 Q5KF69_CRYD1 6ISEA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 331 0 None None Casein kinase II subunit alpha Cryptococcus deneoformans
CMGC CK2 Q5KF69_CRYD1 6ISEB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 331 0 None None Casein kinase II subunit alpha Cryptococcus deneoformans
CMGC CKA1 J9VNH4_CRYN9 6KO6B 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 334 0 None None Casein kinase II subunit alpha Cryptococcus neoformans
OTHER PK1 A0A097P1P8_GVCP 6VVGA 2.01 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 279 0 None None PK-1 Cydia pomonella granulosis virus
OTHER PK1 A0A097P1P8_GVCP 6VVGB 2.01 Active DFGin‑BLAminus na-na in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 3 - 278 0 None None PK-1 Cydia pomonella granulosis virus
CAMK CAMKII KCC2A_DROME 5FG8A 1.955 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 275 0 None None Calcium/calmodulin-dependent protein kinase type II alpha chain Drosophila melanogaster
CAMK CAMKII KCC2A_DROME 5H9BA 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AN2 ATPlike 7 - 275 0 None None Calcium/calmodulin-dependent protein kinase type II alpha chain Drosophila melanogaster
CAMK CAMKII KCC2A_DROME 5HU3A 1.885 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 7 - 272 0 None D136N Calcium/calmodulin-dependent protein kinase type II alpha chain Drosophila melanogaster
CAMK CDPK Q3HNM4_EIMTE 4YSJA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 499 0 None None non-specific serine/threonine protein kinase Eimeria tenella
CAMK CDPK Q3HNM4_EIMTE 4YSJB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 499 0 None None non-specific serine/threonine protein kinase Eimeria tenella
TYR PTK2 FAK1_CHICK 6TY4A 5.96 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 34 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR PTK2 FAK1_CHICK 6TY4B 5.96 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 34 - 686 0 None None Focal adhesion kinase 1 Gallus gallus
TYR SRC SRC_CHICK 3DQWA 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 255 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQWB 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 255 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQWC 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 258 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQWD 2.017 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 257 - 533 0 PTR416 T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3DQXB 2.3 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AMP ATPlike 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
OTHER LPL0262 Q5WZW9_LEGPL 5CKWA 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 404 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
OTHER LPL0262 Q5WZW9_LEGPL 5CKWB 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 1 - 404 0 None None non-specific serine/threonine protein kinase Legionella pneumophila
AGC PRKACA KAPCA_MOUSE 4O21A 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7E11A 3.43 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3PVBA 3.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 7 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 1BKXA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 13 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 1L3RE 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 2 - 351 0 SEP11,SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 2QCSA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3FJQE 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3IDBA 1.62 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3IDCA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DG0E 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 11 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH1A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH3A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH5A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH7A 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DH8A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4HPTE 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4HPUE 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 5JR7A 3.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 5JR7C 3.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7UJXE 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7V0GE 1.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 17 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DFXE 1.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4X6RA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 SEP140,TPO198,SEP339 K8C cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3X2UA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3X2VA 1.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 18 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3X2WA 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IACA 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ACP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IADA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAFA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAIA 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAKA 1.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAYA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IAZA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IB0A 1.87 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IB1A 1.63 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 14 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4IB3A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 13 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4XW4A 1.82 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4XW5A 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4XW6A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 15 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 6E21A 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 16 - 351 0 SEP140,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 7E0ZA 2.162 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 4DG3E 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 351 0 SEP140,TPO198 R337A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3FHIA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 14 - 351 0 TPO198,SEP339 C200A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3QAME 1.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 TPO198,SEP339 E209A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
AGC PRKACA KAPCA_MOUSE 3QALE 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 2 - 351 0 TPO198,SEP339 R281A cAMP-dependent protein kinase catalytic subunit alpha Mus musculus
CAMK CAMK2A KCC2A_MOUSE 7B56B 1.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 307 0 None T305A,T306A Calcium/calmodulin-dependent protein kinase type II subunit alpha Mus musculus
CAMK CAMK2A KCC2A_MOUSE 7B57B 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 5 - 307 0 None T305A,T306A Calcium/calmodulin-dependent protein kinase type II subunit alpha Mus musculus
CAMK DAPK2 DAPK2_MOUSE 2YAAA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 311 0 None None Death-associated protein kinase 2 Mus musculus
CAMK DAPK2 DAPK2_MOUSE 2YABA 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 13 - 311 0 None None Death-associated protein kinase 2 Mus musculus
CMGC GSK3B GSK3B_MOUSE 8VMFA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 27 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
CMGC GSK3B GSK3B_MOUSE 8VMGA 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
CMGC GSK3B GSK3B_MOUSE 8VMEA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
CMGC GSK3B GSK3B_MOUSE 4NU1A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 6 - 383 0 SEP9 None Glycogen synthase kinase-3 beta Mus musculus
CMGC MAPK14 MK14_MOUSE 5NZZE 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 4 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5NZZF 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AGS ATPlike 5 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Mus musculus
TYR LYN LYN_MOUSE 2ZV8A 2.7 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ANP ATPlike 239 - 501 0 None None Tyrosine-protein kinase Lyn Mus musculus
CAMK PHKG1 PHKG1_RABIT 2PHKA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 15 - 291 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Oryctolagus cuniculus
CAMK PHKG1 PHKG1_RABIT 1QL6A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 292 0 None E183S Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Oryctolagus cuniculus
CAMK PHKG1 PHKG1_RABIT 1PHKA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 16 - 292 0 None None Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Oryctolagus cuniculus
OTHER PINK1 PINK1_PEDHC 8UYHA 2.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 115 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYHB 2.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ANP ATPlike 121 - 574 0 TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYIA 3.13 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 120 - 572 0 SEP202,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
OTHER PINK1 PINK1_PEDHC 8UYIB 3.13 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 122 - 574 0 SEP202,TPO305 None Serine/threonine-protein kinase Pink1, mitochondrial Pediculus humanus
CAMK CDPK1 CDPK1_PLABA 3Q5IA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 38 - 518 0 None None Calcium-dependent protein kinase 1 Plasmodium berghei
CMGC PSTK1 Q8IL19_PLAF7 3LLTA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 535 - 875 0 None None Protein serine/threonine kinase-1 Plasmodium falciparum
STE TAOK2 TAOK2_RAT 1U5RA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 320 0 SEP181 None Serine/threonine-protein kinase TAO2 Rattus norvegicus
STE TAOK2 TAOK2_RAT 1U5RB 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 12 - 320 0 SEP181 None Serine/threonine-protein kinase TAO2 Rattus norvegicus
CMGC SKY1 SKY1_YEAST 1Q8YA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 144 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
CMGC SKY1 SKY1_YEAST 1Q97A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 144 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
CMGC SKY1 SKY1_YEAST 1Q99A 2.11 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 143 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
CMGC SKY1 SKY1_YEAST 1Q99B 2.11 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 142 - 737 0 None None Serine/threonine-protein kinase SKY1 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WW7A 1.669 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa AMP ATPlike 4 - 257 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
OTHER BUD32 BUD32_YEAST 4WW9A 1.951 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ADP ATPlike 4 - 259 0 None None EKC/KEOPS complex subunit BUD32 Saccharomyces cerevisiae
TKL NCGRLOCUS634 A0ACD6BAX3_9POAL 8HO6A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 7 - 305 0 TPO184,SEP187,TPO188 None ScRIPK kinase protein Saccharum hybrid cultivar
CK1 CKI1 CKI1_SCHPO 1CSNA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 6 - 298 0 None None Casein kinase I homolog 1 Schizosaccharomyces pombe
AGC PRKACA KAPCA_PIG 1CDKA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Sus scrofa
AGC PRKACA KAPCA_PIG 1CDKB 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 9 - 351 0 TPO198 None cAMP-dependent protein kinase catalytic subunit alpha Sus scrofa
CMGC TVAG125560 A2F9N1_TRIV3 9AV7A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 15 - 318 0 None None non-specific serine/threonine protein kinase Trichomonas vaginalis
CMGC ACK2 CSK2A_MAIZE 1DS5A 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1DS5B 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1DS5C 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1DS5D 3.16 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 1 - 328 0 None None Casein kinase II subunit alpha Zea mays