Ligand: S22

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 100.0% 3GFWA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
OTHER TTK TTK_HUMAN 3GFWA 2.74 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaoni APEdist_nnno S22 Type1 519 - 794 0 None None Dual specificity protein kinase TTK

Ligand: S22

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 100.0% 3GFWA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER TTK TTK_HUMAN 3GFWA 2.74 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaoni APEdist_nnno S22 Type1 519 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens

Ligand: S22

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism