6P5P

ROCK2 (Rho-associated protein kinase 2)
Group: AGC
Uniprot: ROCK2_HUMAN
Organism: Homo sapiens
Domain boundary: 92 - 354
Resolu: 3.3

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in O1V Type1 27 - 417 0
B Inactive DFGin ABAminus in-in in-out O1V Type1 27 - 417 5
C Inactive DFGin ABAminus in-in in-in O1V Type1 28 - 416 0
D Inactive DFGin ABAminus in-in in-out O1V Type1 26 - 416 1
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
        22         32         42         52 
gamgspgdga gasRQRKLEA LIRDPRSPIN VESLLDGLNS 
        62         72         82         92 
LVLDLDFPAL RKNKNIDNFL NRYEKIVKKI RGLQMKAEDY 
       102        112        122        132 
DVVKVIGRGA FGEVQLVRHK ASQKVYAMKL LSKFEMIKRS 
       142        152        162        172 
DSAFFWEERD IMAFANSPWV VQLFYAFQDD RYLYMVMEYM 
       182        192        202        212 
PGGDLVNLMS NYDVPEKWAK FYTAEVVLAL DAIHSMGLIH 
       222        232        242        252 
RDVKPDNMLL DKHGHLKLAD FGTCMKMDET GMVHcDTAVG 
       262        272        282        292 
TPDYISPEVL KSQGGDGYYG RECDWWSVGV FLYEMLVGDT 
       302        312        322        332 
PFYADSLVGT YSKIMDHKNS LCFPedaEIS KHAKNLICAF 
       342        352        362        372 
LTDREVRLGR NGVEEIRQHP FFKNDQWHWD NIRETAAPVV 
       382        392        402        412 
PELSSDIDSS NFDDIEddkg dVETFPIPKA FVGNQLPFIG 

FTYYr
Lower-case residues are disordered in structure.
Mutations: F270Y
Phosphorylation: None