2ZM3

IGF1R (Insulin-like growth factor 1 receptor)
Group: TYR
Uniprot: IGF1R_HUMAN
Organism: Homo sapiens
Domain boundary: 999 - 1268
Resolu: 2.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-out in-in 575 Type1 981 - 1285 0
B Inactive DFGin ABAminus in-out in-in 575 Type1 981 - 1285 0
C Inactive DFGin ABAminus in-out in-in 575 Type1 981 - 1285 0
D Inactive DFGin ABAminus in-out in-in 575 Type1 981 - 1285 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
       988        998       1008       1018 
gSFSAADVYV PDEWEVAREK ITMSRELGQG SFGMVYEGVA 
      1028       1038       1048       1058 
KGVVKDEPET RVAIKTVNEA ASMRERIEFL NEASVMKEFN 
      1068       1078       1088       1098 
CHHVVRLLGV VSQGQPTLVI MELMTRGDLK SYLRSLRPem 
      1108       1118       1128       1138 
ennpvlapPS LSKMIQMAGE IADGMAYLNA NKFVHRDLAA 
      1148       1158       1168       1178 
RNCMVAEDFT VKIGDFGMTR DIYETDYYRK GGKGLLPVRW 
      1188       1198       1208       1218 
MSPESLKDGV FTTYSDVWSF GVVLWEIATL AEQPYQGLSN 
      1228       1238       1248       1258 
EQVLRFVMEG GLLDKPDNCP DMLFELMRMC WQYNPKMRPS 
      1268       1278 
FLEIISSIKE EMEPGFREVS FYYSEENk
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X1161,X1165,X1166