Ligand: 6HL

Total number of chains: 2
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 5J9YA
DFGin ABAminus 1 6QG7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
STE MAP2K7 MP2K7_HUMAN 6QG7A 2.1 Inactive DFGin‑ABAminus in-na in-out 6HL Type1 102 - 401 9 None None Dual specificity mitogen-activated protein kinase kinase 7
TYR EGFR EGFR_HUMAN 5J9YA 2.8 Active DFGin‑BLAminus in-in in-in 6HL Type1 697 - 1019 3 None None Epidermal growth factor receptor

Ligand: 6HL

Total number of chains: 2
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 5J9YA
DFGin ABAminus 1 6QG7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
STE MAP2K7 MP2K7_HUMAN 6QG7A 2.1 Inactive DFGin‑ABAminus in-na in-out 6HL Type1 102 - 401 9 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
TYR EGFR EGFR_HUMAN 5J9YA 2.8 Active DFGin‑BLAminus in-in in-in 6HL Type1 697 - 1019 3 None None Epidermal growth factor receptor Homo sapiens

Ligand: 6HL

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism