| Spatial | Dihedral | Chains | Representative | 
|---|---|---|---|
| DFGin | BLAminus | 1 | 8BUEE | 
| DFGin | ABAminus | 1 | 8BUEH | 
| DFGin | None | 1 | 8BUEB | 
| Group | Gene | UniprotID | Protein | PDB | Resolu | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | 
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CMGC | CDK12 | CDK12_HUMAN | Cyclin-dependent kinase 12 | 8BUEH | 3.25 | Inactive | DFGin | ABAminus | in-in | in-in | RVU | Type1 | 
| CMGC | CDK12 | CDK12_HUMAN | Cyclin-dependent kinase 12 | 8BUEE | 3.25 | Active | DFGin | BLAminus | in-in | in-in | RVU | Type1 | 
| CMGC | CDK12 | CDK12_HUMAN | Cyclin-dependent kinase 12 | 8BUEB | 3.25 | Inactive | DFGin | None | in-in | in-in | RVU | Type1 | 
| Spatial | Dihedral | Chains | Representative | 
|---|---|---|---|
| DFGin | BLAminus | 1 | 8BUEE | 
| DFGin | ABAminus | 1 | 8BUEH | 
| DFGin | None | 1 | 8BUEB | 
| Organism | Group | Gene | UniprotID | Protein | PDB | Resolu | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | 
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Homo sapiens | CMGC | CDK12 | CDK12_HUMAN | Cyclin-dependent kinase 12 | 8BUEH | 3.25 | Inactive | DFGin | ABAminus | in-in | in-in | RVU | Type1 | 
| Homo sapiens | CMGC | CDK12 | CDK12_HUMAN | Cyclin-dependent kinase 12 | 8BUEE | 3.25 | Active | DFGin | BLAminus | in-in | in-in | RVU | Type1 | 
| Homo sapiens | CMGC | CDK12 | CDK12_HUMAN | Cyclin-dependent kinase 12 | 8BUEB | 3.25 | Inactive | DFGin | None | in-in | in-in | RVU | Type1 | 
| Spatial | Dihedral | Chains | Representative | 
|---|
| Organism | Group | Gene | UniprotID | Protein | PDB | Resolu | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | 
|---|