Protein kinases in complex with BI4

Total number of genes: 1
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAminus 5 3OTUA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZA 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZB 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZC 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZD 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3OTUA 2.101 Active DFGin BLAminus in-in in-in J30 BI4 Allosteric Type1.5_Front

Protein kinases in complex with BI4

Total number of genes: 2
Total number of chains: 7
Spatial Dihedral Chains Representative
DFGin BLAminus 6 1SZMA
DFGin ABAminus 1 1SZMB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 1SZMB 2.5 Inactive DFGin ABAminus out-out in-in BI4 Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 1SZMA 2.5 Active DFGin BLAminus in-in in-in BI4 Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZA 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZB 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZC 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZD 2.0 Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3OTUA 2.101 Active DFGin BLAminus in-in in-in J30 BI4 Allosteric Type1.5_Front

Protein kinases in complex with BI4

Total number of genes: 1
Total number of chains: 2
Spatial Dihedral Chains Representative
DFGin BLAminus 1 1SZMA
DFGin ABAminus 1 1SZMB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 1SZMB 2.5 Inactive DFGin ABAminus out-out in-in BI4 Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 1SZMA 2.5 Active DFGin BLAminus in-in in-in BI4 Type1