8R3X

PRKCI (Protein kinase C iota type)
Group: AGC
Uniprot: KPCI_HUMAN
Organism: Homo sapiens
Domain boundary: 254 - 522
Resolu: 2.591

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-out in-in No_ligand No_ligand 249 - 588 0
B Inactive DFGin ABAminus in-in in-in No_ligand No_ligand 249 - 587 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       250        260        270        280 
esgkasssLG LQDFDLLRVI GRGSYAKVLL VRLKKTDRIY 
       290        300        310        320 
AMKVVKKELV NDDEDIDWVQ TEKHVFEQAS NHPFLVGLHS 
       330        340        350        360 
CFQTESRLFF VIEYVNGGDL MFHMQRQRKL PEEHARFYSA 
       370        380        390        400 
EISLALNYLH ERGIIYRDLK LDNVLLDSEG HIKLTDYGMC 
       410        420        430        440 
KEGLRPGDTT STFCGTPNYI APEILRGEDY GFSVDWWALG 
       450        460        470        480 
VLMFEMMAGR SPFDIVGSSD NPDQNTEDYL FQVILEKQIR 
       490        500        510        520 
IPRSLSVKAA SVLKSFLNKD PKERLGCHPQ TGFADIQGHP 
       530        540        550        560 
FFRNVDWDMM EQKQVVPPFK PNISGEFGLD NFDSQFTNEP 
       570        580        590 
VQLTPDDDDI VRKIDQSEFE GFEYINPllm saeecv
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X412,X564