Ligand: YMX (Entrectinib)

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 5KVTA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR ALK ALK_HUMAN 5FTOA 2.22 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai YMX Type1 1094 - 1401 0 None None ALK tyrosine kinase receptor
TYR NTRK1 NTRK1_HUMAN 5KVTA 2.45 Inactive DFGin‑ABAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai YMX Type1 501 - 787 0 None None High affinity nerve growth factor receptor

Ligand: YMX (Entrectinib)

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 5KVTA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR ALK ALK_HUMAN 5FTOA 2.22 Inactive DFGin‑ABAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai YMX Type1 1094 - 1401 0 None None ALK tyrosine kinase receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 5KVTA 2.45 Inactive DFGin‑ABAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai YMX Type1 501 - 787 0 None None High affinity nerve growth factor receptor Homo sapiens

Ligand: YMX (Entrectinib)

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism