Protein kinases in complex with VGH (Crizotinib)

Total number of genes: 3
Total number of chains: 9
Spatial Dihedral Chains Representative
DFGin ABAminus 8 5AAAA
DFGin BLBplus 1 2WGJA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 4ANSA 1.85 Inactive DFGin ABAminus in-out out-out VGH Type1
TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 2YFXA 1.7 Inactive DFGin ABAminus in-out out-out VGH Type1
TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 4ANQA 1.76 Inactive DFGin ABAminus in-out out-out VGH Type1
TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 5AAAA 1.73 Inactive DFGin ABAminus in-out out-out VGH Type1
TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 5AABA 2.2 Inactive DFGin ABAminus in-out out-out VGH Type1
TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 2XP2A 1.9 Inactive DFGin ABAminus in-out out-out VGH Type1
TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 5AACA 1.7 Inactive DFGin ABAminus in-out out-out VGH Type1
TYR MET MET_HUMAN Hepatocyte growth factor receptor 2WGJA 2.0 Inactive DFGin BLBplus out-out out-in VGH Type1
TYR ROS1 ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS 3ZBFA 2.2 Inactive DFGin ABAminus in-in in-out VGH Type1

Protein kinases in complex with VGH

Total number of genes: 3
Total number of chains: 9
Spatial Dihedral Chains Representative
DFGin ABAminus 8 5AAAA
DFGin BLBplus 1 2WGJA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 4ANSA 1.85 Inactive DFGin ABAminus in-out out-out VGH Type1
Homo sapiens TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 2YFXA 1.7 Inactive DFGin ABAminus in-out out-out VGH Type1
Homo sapiens TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 4ANQA 1.76 Inactive DFGin ABAminus in-out out-out VGH Type1
Homo sapiens TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 5AAAA 1.73 Inactive DFGin ABAminus in-out out-out VGH Type1
Homo sapiens TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 5AABA 2.2 Inactive DFGin ABAminus in-out out-out VGH Type1
Homo sapiens TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 2XP2A 1.9 Inactive DFGin ABAminus in-out out-out VGH Type1
Homo sapiens TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 5AACA 1.7 Inactive DFGin ABAminus in-out out-out VGH Type1
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 2WGJA 2.0 Inactive DFGin BLBplus out-out out-in VGH Type1
Homo sapiens TYR ROS1 ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS 3ZBFA 2.2 Inactive DFGin ABAminus in-in in-out VGH Type1

Protein kinases in complex with VGH

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type