All / All / Type1.5_Back

Total number of chains: 567
Active chains: 91
Total number of genes: 77
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 241 42.5% 6RCHA
DFGin BLAplus 116 20.5% 6JUUA
DFGin BLBplus 115 20.3% 5P9IA
DFGin None 37 6.5% 7SIUA
DFGin BLBminus 19 3.4% 7P3VB
DFGin ABAminus 17 3.0% 5UU1A
DFGout None 8 1.4% 2G2HB
DFGout BBAminus 7 1.2% 2XIRA
None None 3 0.5% 5OMHA
DFGin BLBtrans 2 0.4% 9GC5A
DFGinter None 2 0.4% 4ZTSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC AKT2 AKT2_HUMAN 3D0EA 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G93 Type1.5_Back 146 - 480 0 TPO309,TPO451 None RAC-beta serine/threonine-protein kinase
AGC AKT2 AKT2_HUMAN 3D0EB 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G93 Type1.5_Back 146 - 480 0 TPO309,TPO451 None RAC-beta serine/threonine-protein kinase
AGC AKT2 AKT2_HUMAN 3E88A 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 146 - 480 0 TPO309,TPO451 S474D RAC-beta serine/threonine-protein kinase
AGC AKT2 AKT2_HUMAN 3E88B 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 146 - 480 0 TPO309,TPO451 S474D RAC-beta serine/threonine-protein kinase
AGC AKT2 AKT2_HUMAN 3E8DA 2.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 146 - 480 0 TPO309,TPO451 S474D RAC-beta serine/threonine-protein kinase
AGC AKT2 AKT2_HUMAN 3E8DB 2.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 146 - 480 0 TPO309,TPO451 S474D RAC-beta serine/threonine-protein kinase
AGC PDPK1 PDPK1_HUMAN 3QCXA 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 3Q2 Type1.5_Back 73 - 358 0 SEP241 None 3-phosphoinositide-dependent protein kinase 1
AGC ROCK1 ROCK1_HUMAN 3TWJA 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaoii APEdist_iioo 07R Type1.5_Back 7 - 402 0 None None Rho-associated protein kinase 1
CAMK AURKA AURKA_HUMAN 4ZTQA 2.8 Inactive DFGinter‑None DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 4RM Type1.5_Back 127 - 388 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 4ZTSA 2.9 Inactive DFGinter‑None DFGAsp-rot-out out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 4RK Type1.5_Back 127 - 388 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 2C6EA 2.1 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno HPM Type1.5_Back 127 - 389 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 3W2CA 2.45 Inactive None‑None DFGAsp-rot-out out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn N15 Type1.5_Back 128 - 388 0 None None Aurora kinase A
CAMK AURKA AURKA_HUMAN 3W2CG 2.45 Inactive None‑None DFGAsp-rot-out out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn N15 Type1.5_Back 128 - 388 0 None None Aurora kinase A
CAMK CAMK2A KCC2A_HUMAN 6X5GA 1.85 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BCN Type1.5_Back 7 - 274 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha
CAMK CAMKK2 KKCC2_HUMAN 5YV9A 2.53 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 91O Type1.5_Back 160 - 448 0 None None Calcium/calmodulin-dependent protein kinase kinase 2
CAMK CHEK1 CHK1_HUMAN 2E9NA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76A Type1.5_Back 2 - 270 0 None None Serine/threonine-protein kinase Chk1
CAMK CHEK1 CHK1_HUMAN 4FSTA 1.9 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK4 Type1.5_Back 3 - 270 0 None None Serine/threonine-protein kinase Chk1
CAMK CHEK1 CHK1_HUMAN 2AYPA 2.9 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 43A Type1.5_Back 2 - 269 0 None None Serine/threonine-protein kinase Chk1
CAMK CHEK1 CHK1_HUMAN 4FSQA 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK3 Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1
CAMK CHEK1 CHK1_HUMAN 4FTKA 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H9K Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1
CAMK CHEK1 CHK1_HUMAN 4FTLA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in nonTYR APEdihe_aaiii APEdist_iiii H0K Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1
CAMK CHEK1 CHK1_HUMAN 4FTMA 1.9 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1HK Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1
CAMK CHEK1 CHK1_HUMAN 4FTNA 2.02 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2HK Type1.5_Back 3 - 271 0 None None Serine/threonine-protein kinase Chk1
CAMK CHEK1 CHK1_HUMAN 2C3KA 2.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ABO Type1.5_Back 6 - 270 0 None None Serine/threonine-protein kinase Chk1
CAMK CHEK2 CHK2_HUMAN 2YITA 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_oooo YIT Type1.5_Back 211 - 510 0 None None Serine/threonine-protein kinase Chk2
CAMK DAPK1 DAPK1_HUMAN 5AUUA 1.7 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU2 Type1.5_Back 2 - 277 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 5AUWA 1.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out nonTYR APEdihe_aaiii APEdist_iooi QUE Type1.5_Back 2 - 277 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 5AUYA 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out nonTYR APEdihe_aaiii APEdist_iooi MRI Type1.5_Back 2 - 277 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 7CCUA 1.649 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-out nonTYR APEdihe_aaiii APEdist_iooi STL Type1.5_Back 2 - 277 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 7CCVA 1.753 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out nonTYR APEdihe_aaiii APEdist_iooi PIT Type1.5_Back 2 - 277 0 None None Death-associated protein kinase 1
CAMK DAPK1 DAPK1_HUMAN 8IE5A 1.803 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi EZE Type1.5_Back 2 - 277 0 None None Death-associated protein kinase 1
CAMK MELK MELK_HUMAN 5TVTA 2.28 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_nnni 7LV Type1.5_Back 2 - 333 0 None None Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 5TWLA 2.42 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in none-out nonTYR APEdihe_aaioi APEdist_nnni H91 Type1.5_Back 2 - 333 0 None None Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 5MAFA 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn XIN Type1.5_Back 2 - 333 0 None None Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2PA 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2PB 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnii 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2PC 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2PD 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4UMPA 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4UMPB 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaini APEdist_nnoi 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4UMPC 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4UMQA 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaoii APEdist_nnoo B5S Type1.5_Back 5 - 333 0 None T167A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
CAMK PIM1 PIM1_HUMAN 3T9IA 2.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3T9 Type1.5_Back 33 - 306 0 SEP261 None Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 6AYDA 3.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii C2J Type1.5_Back 34 - 305 0 None R250G Serine/threonine-protein kinase pim-1
CAMK STK17B ST17B_HUMAN 3LM5A 2.29 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-out nonTYR APEdihe_aaiii APEdist_nnoo QUE Type1.5_Back 25 - 301 0 None None Serine/threonine-protein kinase 17B
CK1 CSNK1D KC1D_HUMAN 6RCHA 1.45 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii K0B Type1.5_Back 2 - 294 0 None None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 6RU7A 2.08 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 3 - 294 0 None None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 6RU7B 2.08 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 3 - 294 0 None None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 6RU8A 1.92 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 2 - 294 0 None None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 6RU8B 1.92 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 2 - 294 0 None None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 6RU8C 1.92 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 2 - 294 0 None None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 6RU8D 1.92 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 2 - 294 0 None None Casein kinase I isoform delta
CK1 CSNK1G3 KC1G3_HUMAN 4HGSA 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iioi 15G Type1.5_Back 34 - 334 0 None None Casein kinase I isoform gamma-3
CK1 TTBK1 TTBK1_HUMAN 7ZHNA 1.85 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VP7 Type1.5_Back 21 - 313 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 7ZHOA 2.08 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQR Type1.5_Back 21 - 317 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 7ZHPA 1.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQY Type1.5_Back 21 - 313 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 7ZHQA 1.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IRD Type1.5_Back 21 - 313 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 7JXXA 1.56 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VP7 Type1.5_Back 22 - 312 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 7JXYA 2.15 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VSY Type1.5_Back 23 - 312 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 7JXYB 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_iini VSY Type1.5_Back 20 - 312 0 None None Tau-tubulin kinase 1
CK1 TTBK1 TTBK1_HUMAN 4BTKA 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iiii DTQ Type1.5_Back 22 - 311 0 None None Tau-tubulin kinase 1
CK1 VRK1 VRK1_HUMAN 5UVFC 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 7DZ Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 5UVFD 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 7DZ Type1.5_Back 25 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6BP0D 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii E1D Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6BRUB 1.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oooi E5M Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6BRUD 1.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oioi E5M Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6BTWA 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi E8D Type1.5_Back 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6BTWD 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii E8D Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6BU6A 1.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi E8V Type1.5_Back 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CFMA 2.45 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi EA7 Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CFMB 2.45 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EA7 Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CFMD 2.45 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EA7 Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CNXB 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F87 Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CNXC 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_nooi FCS Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CNXD 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F87 Type1.5_Back 24 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6NPNA 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi KWJ Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6NPNB 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii KWJ Type1.5_Back 24 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6NPNC 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi KWJ Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6NPND 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii KWJ Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6VXUC 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi VBD Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6VZHB 2.55 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oioi RYA Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6VZHD 2.55 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii RYA Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 9ZKGC 2.06 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii A1C2O Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 9ZKGD 2.06 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii A1C2O Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK2 VRK2_HUMAN 5UU1A 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 7DZ Type1.5_Back 14 - 328 0 None None Serine/threonine-protein kinase VRK2
CK1 VRK2 VRK2_HUMAN 6NCGA 2.45 Inactive DFGin‑BLAminus DFGAsp-rot-in in-none in-out nonTYR APEdihe_aaiii APEdist_iooi KJD Type1.5_Back 14 - 326 0 None None Serine/threonine-protein kinase VRK2
CK1 VRK2 VRK2_HUMAN 6NCGB 2.45 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none nonTYR APEdihe_aaiii APEdist_nnii KJD Type1.5_Back 16 - 326 0 None None Serine/threonine-protein kinase VRK2
CK1 VRK2 VRK2_HUMAN 9FETA 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii REB Type1.5_Back 15 - 330 0 None None Serine/threonine-protein kinase VRK2
CMGC CDK2 CDK2_HUMAN 3F5XA 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iioi EZV Type1.5_Back 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3F5XC 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iiii EZV Type1.5_Back 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3BHUC 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii MHR Type1.5_Back 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK9 CDK9_HUMAN 4IMYA 2.94 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP Type1.5_Back 8 - 330 0 TPO186 None Cyclin-dependent kinase 9
CMGC CSNK2A1 CSK21_HUMAN 6L22A 2.123 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iiii E3U Type1.5_Back 2 - 335 0 None H115Y Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5OWHA 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-in nonTYR APEdihe_aaiii APEdist_iiii B0K Type1.5_Back 2 - 335 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 7BU4A 1.702 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iiii Y49 Type1.5_Back 2 - 335 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 6L21A 2.055 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iiii E3U Type1.5_Back 2 - 332 0 None H160A Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 7I84A 1.97 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1BZY Type1.5_Back 3 - 329 0 None R21S,K74A,K75A,K76A Casein kinase II subunit alpha
CMGC DYRK1A DYR1A_HUMAN 8C3QA 2.32 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RUT Type1.5_Back 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 8C3QB 2.32 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RUT Type1.5_Back 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC GSK3B GSK3B_HUMAN 5OY4A 3.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4K Type1.5_Back 36 - 385 0 PTR216 None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 5OY4B 3.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4K Type1.5_Back 30 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 4IQ6B 3.12 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQ6 Type1.5_Back 37 - 382 0 None None Glycogen synthase kinase-3 beta
CMGC MAPK10 MK10_HUMAN 2O0UA 2.1 Inactive DFGin‑ABAminus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaiii APEdist_oooo C0M Type1.5_Back 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK14 MK14_HUMAN 6TCAB 3.7 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaioi APEdist_iiii 39G Type1.5_Back 6 - 354 0 TPO180,PTR182 None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6TCAD 3.7 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaooi APEdist_iioi 39G Type1.5_Back 4 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6TCAF 3.7 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaioi APEdist_iioi 39G Type1.5_Back 6 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6TCAH 3.7 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 39G Type1.5_Back 4 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2ZB1A 2.5 Inactive DFGin‑BLBminus DFGAsp-rot-out in-in none-out nonTYR APEdihe_aaooi APEdist_oooo GK4 Type1.5_Back 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 5XYXA 2.61 Inactive DFGin‑BLBminus DFGAsp-rot-out in-in none-out nonTYR APEdihe_aaooi APEdist_nnno FTZ Type1.5_Back 4 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 5XYYA 1.7 Inactive DFGin‑BLBminus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aaooi APEdist_oooo P0F Type1.5_Back 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2RG5A 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 279 Type1.5_Back 4 - 351 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3BX5A 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-none nonTYR APEdihe_aanii APEdist_nnnn 304 Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3L8XA 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aaooi APEdist_nnno N4D Type1.5_Back 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 5OMHA 2.5 Inactive None‑None DFGAsp-rot-out in-out none-out nonTYR APEdihe_aaooi APEdist_nnno 9Y5 Type1.5_Back 5 - 353 0 None None Mitogen-activated protein kinase 14
OTHER EIF2AK3 E2AK3_HUMAN 4G31A 2.28 Inactive DFGin‑None DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 0WH Type1.5_Back 588 - 1080 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 4G34A 2.7 Inactive DFGin‑None DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 924 Type1.5_Back 588 - 1079 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 4M7IA 2.34 Inactive DFGin‑None DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 27D Type1.5_Back 588 - 1080 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 8EQEAAA 2.559 Inactive DFGin‑None DFGAsp-rot-in out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn WQ2 Type1.5_Back 585 - 1080 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3OA 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-out out-out out-none nonTYR APEdihe_aanai APEdist_nnnn KA7 Type1.5_Back 584 - 1004 0 None K807A,D848N,T899E,T904E eIF-2-alpha kinase GCN2
OTHER ERN1 ERN1_HUMAN 6W3EB 2.737 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaooi APEdist_nnoo SJV Type1.5_Back 563 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6XDFA 2.54 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_iooi N94 Type1.5_Back 560 - 966 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 7BMKA 1.85 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_iooi U4N Type1.5_Back 561 - 966 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 7BMKB 1.85 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_ioio U4N Type1.5_Back 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6URCA 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_iooi QFV Type1.5_Back 560 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6URCB 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_iooi QFV Type1.5_Back 560 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6XDDB 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in nonTYR APEdihe_aaiii APEdist_iiii N97 Type1.5_Back 560 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4U6RA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_iioi 3E4 Type1.5_Back 561 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6XDBA 2.45 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_iooi N8S Type1.5_Back 561 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER GAK GAK_HUMAN 4C58A 2.16 Inactive DFGin‑ABAminus DFGAsp-rot-out in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 824 Type1.5_Back 27 - 333 0 None None Cyclin-G-associated kinase
OTHER HASPIN HASP_HUMAN 6Z56A 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q7Q Type1.5_Back 470 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 6Z5BA 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q7Z Type1.5_Back 469 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER HASPIN HASP_HUMAN 9FLCA 2.18 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDA Type1.5_Back 471 - 798 0 None None Serine/threonine-protein kinase haspin
OTHER PKMYT1 PMYT1_HUMAN 9LGVA 2.041 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJV Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 9LIDA 2.06 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJX Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 9LIDB 2.06 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJX Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 9LGNA 2.03 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJU Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 9LGNB 2.03 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJU Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8D6DA 2.35 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGY Type1.5_Back 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8D6EA 2.15 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGI Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8D6FA 2.49 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QG5 Type1.5_Back 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 8D6FB 2.49 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QG5 Type1.5_Back 76 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER PKMYT1 PMYT1_HUMAN 9M6PBBB 2.383 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiai APEdist_iiii A1EMX Type1.5_Back 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER TTK TTK_HUMAN 6TNDA 2.58 Inactive DFGin‑ABAminus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 8RH Type1.5_Back 516 - 793 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3W1FA 2.7 Inactive DFGin‑ABAminus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 1O5 Type1.5_Back 516 - 795 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3WZJA 2.75 Inactive DFGin‑ABAminus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aaioi APEdist_nnno O43 Type1.5_Back 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 3WZKA 2.3 Inactive DFGin‑ABAminus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aaioi APEdist_nnno O23 Type1.5_Back 516 - 794 0 None None Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5NADA 2.8 Inactive DFGin‑ABAminus DFGAsp-rot-out in-in out-none nonTYR APEdihe_aanni APEdist_nnnn 8RH Type1.5_Back 519 - 794 0 TPO686 None Dual specificity protein kinase TTK
STE MAP2K1 MP2K1_HUMAN 7XLPA 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaioi APEdist_nnno FZC Type1.5_Back 37 - 382 0 None S298N,S299K,Y300K Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K7 MP2K7_HUMAN 7OVKA 2.05 Inactive DFGin‑None DFGAsp-rot-in na-na none-none nonTYR APEdihe_aannn APEdist_nnnn 2I5 Type1.5_Back 102 - 401 0 None None Dual specificity mitogen-activated protein kinase kinase 7
STE MAP3K14 M3K14_HUMAN 4IDVA 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 13V Type1.5_Back 331 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14
STE MAP3K14 M3K14_HUMAN 4IDVB 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 13V Type1.5_Back 331 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14
STE MAP3K14 M3K14_HUMAN 4IDVC 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 13V Type1.5_Back 331 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14
STE MAP3K14 M3K14_HUMAN 4IDVD 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 13V Type1.5_Back 331 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14
STE MAP4K1 M4K1_HUMAN 9BJ1B 2.18 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in out-out nonTYR APEdihe_aaioi APEdist_oooo A1APQ Type1.5_Back 5 - 293 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 7SIUA 1.786 Inactive DFGin‑None DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaioi APEdist_oioo 9ID Type1.5_Back 5 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 7SIUB 1.786 Inactive DFGin‑None DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 9ID Type1.5_Back 16 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K4 M4K4_HUMAN 5W5QA 2.33 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 9X4 Type1.5_Back 17 - 311 0 None None Mitogen-activated protein kinase kinase kinase kinase 4
STE PAK1 PAK1_HUMAN 4EQCA 2.01 Inactive DFGin‑BLAminus DFGAsp-rot-out out-none in-in nonTYR APEdihe_aaiii APEdist_iiii XR1 Type1.5_Back 249 - 541 0 TPO423 K299R Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 5DEYA 2.1 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 59T Type1.5_Back 250 - 544 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4O0TA 2.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2OL Type1.5_Back 251 - 542 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 5IMEA 2.217 Inactive DFGin‑BLAminus DFGAsp-rot-out out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6BZ Type1.5_Back 251 - 545 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 9N4UA 1.77 Inactive DFGin‑BLAminus DFGAsp-rot-out out-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BV8 Type1.5_Back 249 - 545 0 None None Serine/threonine-protein kinase PAK 1
STE PAK4 PAK4_HUMAN 7CP3A 2.9 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GC6 Type1.5_Back 300 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 7CP4A 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GCC Type1.5_Back 300 - 591 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 7CMBA 2.592 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G5X Type1.5_Back 300 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 4O0VA 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2OL Type1.5_Back 300 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 4O0XA 2.483 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2OQ Type1.5_Back 300 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE PAK4 PAK4_HUMAN 4O0YA 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2OO Type1.5_Back 300 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4
STE STK24 STK24_HUMAN 4QMWA 1.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KS1 Type1.5_Back 24 - 310 0 TPO190 None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 8BZIA 1.72 Inactive DFGin‑BLBminus DFGAsp-rot-out out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SJL Type1.5_Back 26 - 301 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 8BZJA 2.52 Inactive DFGin‑BLBminus DFGAsp-rot-out out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SJX Type1.5_Back 26 - 301 0 None None Serine/threonine-protein kinase 24
STE STK26 STK26_HUMAN 7B36C 2.107 Inactive DFGin‑BLBminus DFGAsp-rot-out out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 59T Type1.5_Back 17 - 299 0 None None Serine/threonine-protein kinase 26
STE TNIK TNIK_HUMAN 8ZMLA 2.489 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1D8H Type1.5_Back 11 - 312 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase
TKL BRAF BRAF_HUMAN 3PPJA 3.7 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_nnno FOI Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3PPJB 3.7 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_nioo FOI Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7SHVB 2.88 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_nnio 29L Type1.5_Back 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4CQEA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaoii APEdist_nnno CQE Type1.5_Back 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JRQA 2.287 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 6N9 Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JRQB 2.287 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 6N9 Type1.5_Back 448 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JSMB 2.19 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 6NB Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JSMC 2.19 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NB Type1.5_Back 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JT2A 2.702 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NC Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5JT2C 2.702 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NC Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4RZVA 2.994 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaiii APEdist_nioo 032 Type1.5_Back 449 - 721 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4RZVB 2.994 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaiii APEdist_iioo 032 Type1.5_Back 449 - 722 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV1A 2.47 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 904 Type1.5_Back 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV3A 2.8 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno P02 Type1.5_Back 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4FK3A 2.65 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 325 Type1.5_Back 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6UUOB 3.288 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaooi APEdist_nnno QH1 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5ITAA 1.95 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 6DC Type1.5_Back 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4WO5A 2.83 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaooo APEdist_iooo 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4WO5B 2.83 Inactive DFGin‑BLAplus DFGAsp-rot-in out-none out-out nonTYR APEdihe_aaiii APEdist_nnno 324 Type1.5_Back 450 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3OG7A 2.45 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 032 Type1.5_Back 449 - 720 0 None K522A,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4EHGA 3.5 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaioi APEdist_nnno RI9 Type1.5_Back 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4EHGB 3.5 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo RI9 Type1.5_Back 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5FD2A 2.89 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 5XJ Type1.5_Back 448 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3TV4A 3.4 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo TV4 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3TV4B 3.4 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_iooo TV4 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3TV6A 3.3 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo B0R Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3TV6B 3.3 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_iooo B0R Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4E4XA 3.6 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_nooo T1Q Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4E4XB 3.6 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_iooo T1Q Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4EHEA 3.3 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo RI8 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4EHEB 3.3 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_iooo RI8 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4PP7A 3.4 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaoii APEdist_nooo 2VX Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4PP7B 3.4 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_iooo 2VX Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8VYSA 3.06 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1AEN Type1.5_Back 235 - 738 0 SEP365,SEP729 V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7P3VA 2.37 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 5I4 Type1.5_Back 448 - 719 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7P3VB 2.37 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_oooo 5I4 Type1.5_Back 448 - 719 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4CQEB 2.3 Inactive DFGin‑BLBminus DFGAsp-rot-in in-out none-out nonTYR APEdihe_aaoii APEdist_nnno CQE Type1.5_Back 448 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV2A 2.5 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno P06 Type1.5_Back 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV2B 2.5 Inactive DFGin‑BLBminus DFGAsp-rot-in in-out none-out nonTYR APEdihe_aaoii APEdist_nnno P06 Type1.5_Back 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5CSWB 2.66 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out none-none nonTYR APEdihe_aanii APEdist_nnnn P06 Type1.5_Back 447 - 721 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6V2UB 3.78 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out none-none nonTYR APEdihe_aanii APEdist_nnnn P06 Type1.5_Back 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3C4CA 2.57 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5CSWA 2.66 Inactive DFGin‑None DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaoii APEdist_nnno P06 Type1.5_Back 449 - 721 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5ITAB 1.95 Inactive DFGin‑None DFGAsp-rot-in out-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6DC Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6V2UA 3.78 Inactive DFGin‑None DFGAsp-rot-in out-none none-out nonTYR APEdihe_aaiii APEdist_nnno P06 Type1.5_Back 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MBJA 3.6 Inactive DFGin‑None DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaioi APEdist_nooo DFS Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MBJB 3.6 Inactive DFGin‑None DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaioi APEdist_iooo DFS Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5CSXA 2.51 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 54J Type1.5_Back 448 - 720 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3C4CB 2.57 Inactive DFGout‑None DFGAsp-rot-in in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL IRAK4 IRAK4_HUMAN 5T1SB 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 76Q Type1.5_Back 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4
TKL KSR2 KSR2_HUMAN 5KKRB 3.509 Pseudo DFGin‑BLBplus DFGAsp-rot-in out-none out-out nonTYR APEdihe_aaoai APEdist_oooo 6U7 Type1.5_Back 650 - 932 0 None None Kinase suppressor of Ras 2
TKL LIMK1 LIMK1_HUMAN 7ATSA 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none none-none nonTYR APEdihe_aannn APEdist_nnnn RXQ Type1.5_Back 330 - 634 0 None None LIM domain kinase 1
TKL MAP3K20 M3K20_HUMAN 5HESA 2.14 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 032 Type1.5_Back 6 - 299 0 TPO161 None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 5X5OA 1.868 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaoii APEdist_oioo 7Z0 Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 6JUTA 2.1 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_iioo C9O Type1.5_Back 8 - 304 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 6JUUA 1.903 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_oioo C9R Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 7YAWA 2.1 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_oioo IGS Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 7YAWD 2.1 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_oooo IGS Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL MAP3K20 M3K20_HUMAN 7YAZA 2.54 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_oioo IGV Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20
TKL RAF1 RAF1_HUMAN 9O0UE 2.91 Inactive DFGin‑BLAplus DFGAsp-rot-in out-none none-out nonTYR APEdihe_aaioi APEdist_nnno 324 Type1.5_Back 339 - 613 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0VE 3.5 Inactive DFGin‑BLAplus DFGAsp-rot-in out-none none-out nonTYR APEdihe_aaioi APEdist_iioo 324 Type1.5_Back 339 - 613 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0UA 2.91 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none out-out nonTYR APEdihe_aaioi APEdist_oooo 324 Type1.5_Back 339 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0VA 3.5 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none out-out nonTYR APEdihe_aaioi APEdist_oioo 324 Type1.5_Back 339 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RIPK2 RIPK2_HUMAN 6UL8A 2.68 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_nnno Q9J Type1.5_Back 5 - 310 0 None C7S,S168C Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6UL8B 2.68 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_nnno Q9J Type1.5_Back 5 - 310 0 None C7S,S168C Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6RN8A 2.69 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out nonTYR APEdihe_aaioi APEdist_nnno K9T Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6RN8B 2.69 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out nonTYR APEdihe_aaioi APEdist_nioo K9T Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6RNAA 2.62 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo KA2 Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6RNAB 2.62 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out nonTYR APEdihe_aaioi APEdist_nioo KA2 Type1.5_Back 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 8X2OA 2.26 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaoni APEdist_nnno 6IL Type1.5_Back 8 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 8X2OB 2.26 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out nonTYR APEdihe_aaooi APEdist_nnno 6IL Type1.5_Back 9 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR8B 2.79 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo XYW Type1.5_Back 8 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR8A 2.79 Inactive DFGin‑None DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno XYW Type1.5_Back 9 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK3 RIPK3_HUMAN 7MX3A 3.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ZOV Type1.5_Back 12 - 314 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MX3C 3.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ZOV Type1.5_Back 9 - 311 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MX3D 3.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ZOV Type1.5_Back 12 - 311 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 9LFUA 2.93 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none nonTYR APEdihe_aanii APEdist_nnnn A1D97 Type1.5_Back 5 - 308 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 9LFUB 2.93 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1D97 Type1.5_Back 5 - 309 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3
TKL TGFBR1 TGFR1_HUMAN 4X2JA 1.69 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3WN Type1.5_Back 200 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 4X2KA 1.69 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3WO Type1.5_Back 200 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 5QIMA 1.75 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J2Y Type1.5_Back 200 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 6B8YA 1.65 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D0A Type1.5_Back 200 - 502 0 None T204D TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OC 3.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OD 3.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OE 3.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3KCFA 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3KCFB 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3KCFC 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3KCFD 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3KCFE 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1
TYR ABL1 ABL1_HUMAN 2GQGB 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1N1 Type1.5_Back 229 - 499 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 8I7TA 2.8 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa 6I5 Type1.5_Back 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HZIB 1.7 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa JIN Type1.5_Back 233 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G2HB 2.0 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa P16 Type1.5_Back 233 - 504 0 None H396P Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2FO0A 2.27 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa P16 Type1.5_Back 46 - 511 0 SEP50 D363N Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 1OPLA 3.42 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa P16 Type1.5_Back 62 - 512 0 None K12R,D363N Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 1OPLB 3.42 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa P16 Type1.5_Back 121 - 499 0 None K12R,D363N Tyrosine-protein kinase ABL1
TYR BTK BTK_HUMAN 6J6MA 1.25 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa BA0 Type1.5_Back 393 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7R61A 1.52 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 2IJ Type1.5_Back 390 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6DI3A 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa GJA Type1.5_Back 393 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6DI5A 1.42 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa GJ7 Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6N9PA 2.23 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa KHD Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6OMUA 1.41 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa MZJ Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7L5OA 1.21 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa R1L Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7L5PA 2.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa R1L Type1.5_Back 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7L5PB 2.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa R1L Type1.5_Back 393 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7R60A 1.94 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 2IE Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8E2MA 1.904 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa UB6 Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W7OA 2.17 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa TL7 Type1.5_Back 396 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W7OB 2.17 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa TL7 Type1.5_Back 396 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W8IC 3.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa TKY Type1.5_Back 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8DSOB 2.334 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_iooai APEdist_aaaa TOO Type1.5_Back 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4YHFA 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa 4C9 Type1.5_Back 391 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4YHFB 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 4C9 Type1.5_Back 390 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9IA 1.11 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 1E8 Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9JA 1.08 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 8E8 Type1.5_Back 394 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9MA 1.41 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 7GB Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3GENA 1.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa B43 Type1.5_Back 392 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6E4FA 1.15 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa HRA Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3PJ2A 1.75 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 04K Type1.5_Back 391 - 659 0 None None Tyrosine-protein kinase BTK
TYR CSF1R CSF1R_HUMAN 3DPKA 1.95 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa 8C5 Type1.5_Back 548 - 912 0 None None Macrophage colony-stimulating factor 1 receptor
TYR EGFR EGFR_HUMAN 8D73A 2.17 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QCR Type1.5_Back 703 - 1011 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8D73B 2.17 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QCR Type1.5_Back 704 - 1012 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8D76A 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QFO Type1.5_Back 703 - 1014 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8D76B 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QFO Type1.5_Back 702 - 1014 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6D8EA 2.537 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa FZP Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GL9A 2.147 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IMT Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9FRDA 2.06 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IEZ Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GI9A 3.12 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1ILZ Type1.5_Back 696 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8F1ZA 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa X9B Type1.5_Back 695 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9QXNAAA 2.142 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1JBI Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RJ5A 3.1 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 3QY Type1.5_Back 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CAQA 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZJ Type1.5_Back 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CASA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZQ Type1.5_Back 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CAUA 2.25 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZR Type1.5_Back 696 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HCYA 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 60D Type1.5_Back 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HICA 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 63N Type1.5_Back 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4R5SA 3.001 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out TYR APEdihe_nnoao APEdist_aaaa FI3 Type1.5_Back 697 - 1018 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9DF2A 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IMS Type1.5_Back 701 - 1004 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9DF3A 1.68 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IMS Type1.5_Back 701 - 1022 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9DF4A 1.78 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1A4E Type1.5_Back 701 - 1019 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9FQPA 2.495 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IEZ Type1.5_Back 701 - 1020 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9FQSA 1.783 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IE0 Type1.5_Back 701 - 1019 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GL7A 1.878 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IMS Type1.5_Back 702 - 1019 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GL8A 1.632 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IMT Type1.5_Back 701 - 1021 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFUB 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out out-none none-none TYR APEdihe_nniai APEdist_aaaa N7K Type1.5_Back 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5EDQA 2.8 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 5N3 Type1.5_Back 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5EM6A 2.78 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 5Q3 Type1.5_Back 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GNKA 1.796 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 80U Type1.5_Back 697 - 985 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WA2A 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa TOV Type1.5_Back 699 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WA2B 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WA2C 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WA2D 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3C 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa YA6 Type1.5_Back 701 - 1009 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV4D 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa YAA Type1.5_Back 701 - 1005 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFUA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa N7K Type1.5_Back 700 - 982 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFVA 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none none-none TYR APEdihe_niiai APEdist_aaaa N7Q Type1.5_Back 700 - 985 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFVB 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa N7Q Type1.5_Back 698 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFWA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa N7W Type1.5_Back 700 - 982 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFWB 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa N7W Type1.5_Back 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFYB 1.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa N7Z Type1.5_Back 699 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFZA 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none none-none TYR APEdihe_niiai APEdist_aaaa N7B Type1.5_Back 701 - 982 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFZB 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none out-none TYR APEdihe_nniai APEdist_aaaa N7B Type1.5_Back 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TG0A 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa N78 Type1.5_Back 700 - 985 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TG0B 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa N78 Type1.5_Back 698 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TG1A 1.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa N82 Type1.5_Back 699 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TG1B 1.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none none-none TYR APEdihe_nniai APEdist_aaaa N82 Type1.5_Back 698 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2JIVB 3.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_ooiai APEdist_aaaa HKI Type1.5_Back 699 - 982 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYB 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1.5_Back 700 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYD 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1.5_Back 701 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYE 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1.5_Back 701 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYG 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1.5_Back 699 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYH 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1.5_Back 700 - 1016 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W2RA 2.05 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa W2R Type1.5_Back 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2RGPA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa HYZ Type1.5_Back 702 - 1016 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3BELA 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa POX Type1.5_Back 702 - 1015 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO4A 1.621 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 26X Type1.5_Back 700 - 1014 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBA 2.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa ITI Type1.5_Back 703 - 983 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBB 2.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa ITI Type1.5_Back 703 - 983 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBC 2.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa ITI Type1.5_Back 704 - 983 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBD 2.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa ITI Type1.5_Back 703 - 983 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3POZA 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa 03P Type1.5_Back 701 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W2SA 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa W2R Type1.5_Back 701 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W32A 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa W32 Type1.5_Back 701 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W33A 1.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa W19 Type1.5_Back 701 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 1XKKA 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_nnoai APEdist_aaaa FMM Type1.5_Back 702 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO1A 2.11 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 2EI Type1.5_Back 699 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO2A 2.28 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 26X Type1.5_Back 705 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO2B 2.28 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 26X Type1.5_Back 702 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9EWSA 2.435 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1H7N Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9EWTA 3.019 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1H7O Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9EWTB 3.019 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1H7O Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GC4A 2.415 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa A1IZ7 Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GC4B 2.415 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa A1IZ7 Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9HBOA 2.45 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-none TYR APEdihe_niiai APEdist_aaaa A1IUK Type1.5_Back 702 - 986 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9HBOB 2.45 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-in TYR APEdihe_iiiai APEdist_aaaa A1IUK Type1.5_Back 702 - 985 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GC5A 1.909 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1IZ8 Type1.5_Back 699 - 1012 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GC5B 1.909 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1IZ8 Type1.5_Back 699 - 1012 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2JIVA 3.5 Inactive DFGin‑None DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa HKI Type1.5_Back 700 - 984 0 None T790M Epidermal growth factor receptor
TYR EPHA2 EPHA2_HUMAN 5NK3A 1.586 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 92Q Type1.5_Back 601 - 888 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8QQYA 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa WT3 Type1.5_Back 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BIOA 1.6 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa QRD Type1.5_Back 605 - 894 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5IA2A 1.619 Inactive DFGin‑BLBminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa L66 Type1.5_Back 598 - 888 0 None None Ephrin type-A receptor 2
TYR EPHA3 EPHA3_HUMAN 4G2FA 1.699 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa C07 Type1.5_Back 609 - 903 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4GK2A 2.195 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa L66 Type1.5_Back 609 - 903 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4GK4A 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa L90 Type1.5_Back 609 - 903 0 None None Ephrin type-A receptor 3
TYR EPHB1 EPHB1_HUMAN 5MJAA 2.14 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 7O3 Type1.5_Back 609 - 892 0 PTR647,PTR778 None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 5MJBA 2.23 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 7O3 Type1.5_Back 608 - 891 0 PTR647,PTR778 None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 6UMWA 1.982 Inactive DFGin‑None DFGAsp-rot-in in-out none-none TYR APEdihe_nniai APEdist_aaaa CTC Type1.5_Back 611 - 889 0 PTR647 None Ephrin type-B receptor 1
TYR EPHB4 EPHB4_HUMAN 2XVDA 1.7 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa AS6 Type1.5_Back 607 - 888 0 None Y774E Ephrin type-B receptor 4
TYR ERBB2 ERBB2_HUMAN 7PCDA 1.77 Inactive DFGin‑BLBminus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 70I Type1.5_Back 710 - 991 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHA 3.27 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa VOY Type1.5_Back 706 - 992 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHE 3.27 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nnnai APEdist_aaaa VOY Type1.5_Back 709 - 992 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHB 3.27 Inactive DFGin‑None DFGAsp-rot-in out-out none-out TYR APEdihe_oiiai APEdist_aaaa VOY Type1.5_Back 707 - 996 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHC 3.27 Inactive DFGin‑None DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa VOY Type1.5_Back 707 - 992 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHD 3.27 Inactive DFGin‑None DFGAsp-rot-in out-out in-none TYR APEdihe_niiai APEdist_aaaa VOY Type1.5_Back 707 - 992 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHF 3.27 Inactive DFGin‑None DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VOY Type1.5_Back 713 - 991 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHG 3.27 Inactive DFGin‑None DFGAsp-rot-in out-out in-none TYR APEdihe_nniai APEdist_aaaa VOY Type1.5_Back 706 - 992 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHH 3.27 Inactive DFGin‑None DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa VOY Type1.5_Back 707 - 992 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 3PP0A 2.25 Inactive DFGin‑None DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa 03Q Type1.5_Back 706 - 993 0 None M706A,Q711L,M712L Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 3PP0B 2.25 Inactive DFGin‑None DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 03Q Type1.5_Back 706 - 1009 0 None M706A,Q711L,M712L Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 3RCDA 3.21 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 03P Type1.5_Back 713 - 1022 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 3RCDC 3.21 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 03P Type1.5_Back 713 - 1022 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB4 ERBB4_HUMAN 2R4BA 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-out TYR APEdihe_oiiai APEdist_aaaa GW7 Type1.5_Back 694 - 991 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 2R4BB 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-out TYR APEdihe_oiiai APEdist_aaaa GW7 Type1.5_Back 694 - 991 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 3BBTB 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa FMM Type1.5_Back 708 - 998 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 3BBTD 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa FMM Type1.5_Back 709 - 988 0 None None Receptor tyrosine-protein kinase erbB-4
TYR FGFR1 FGFR1_HUMAN 4RWKB 2.982 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 66T Type1.5_Back 459 - 763 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3C4FA 2.07 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_iioai APEdist_aaaa C4F Type1.5_Back 464 - 765 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3C4FB 2.07 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa C4F Type1.5_Back 464 - 765 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3RHXA 2.01 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 3RH Type1.5_Back 464 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3RHXB 2.01 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 3RH Type1.5_Back 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5A4CA 2.09 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa XOJ Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5A4CB 2.09 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa XOJ Type1.5_Back 461 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4NK9B 2.57 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 2K5 Type1.5_Back 460 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4V05A 2.57 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 66T Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4V05B 2.57 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 66T Type1.5_Back 459 - 764 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5EW8A 1.63 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5SF Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5EW8B 1.63 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5SF Type1.5_Back 461 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 2FGIA 2.5 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa PD1 Type1.5_Back 464 - 762 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 2FGIB 2.5 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa PD1 Type1.5_Back 461 - 761 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5B7VA 2.15 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa LWJ Type1.5_Back 464 - 763 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4WUNA 1.65 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa 66T Type1.5_Back 465 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4WUNB 1.65 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa 66T Type1.5_Back 461 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5UR1A 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY9 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C18A 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY5 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C19A 2.12 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa YY7 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C19B 2.12 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa YY7 Type1.5_Back 464 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1BA 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY4 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1BB 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa YY4 Type1.5_Back 463 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1CA 2.15 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY6 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1CB 2.15 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa YY6 Type1.5_Back 463 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1OA 2.29 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa MK9 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1OB 2.29 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa MK9 Type1.5_Back 464 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6MZQA 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa TZ0 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6MZQB 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa TZ0 Type1.5_Back 462 - 761 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWJA 2.489 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 66T Type1.5_Back 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWJB 2.489 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 66T Type1.5_Back 459 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3GQLA 2.8 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_oooai APEdist_aaaa GQL Type1.5_Back 463 - 774 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3TT0A 2.8 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 07J Type1.5_Back 461 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3TT0B 2.8 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnnao APEdist_aaaa 07J Type1.5_Back 459 - 763 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8Y22A 2.792 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1LW9 Type1.5_Back 459 - 762 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8Y22B 2.792 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1LW9 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLA 2.7 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa XL6 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLB 2.7 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL6 Type1.5_Back 461 - 761 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLC 2.7 Inactive DFGin‑BLAplus DFGAsp-rot-none in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL6 Type1.5_Back 465 - 761 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLD 2.7 Inactive DFGin‑BLAplus DFGAsp-rot-out in-none none-out TYR APEdihe_iioai APEdist_aaaa XL6 Type1.5_Back 471 - 762 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7WCLA 2.495 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 8ZF Type1.5_Back 459 - 764 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7WCLB 2.495 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 8ZF Type1.5_Back 458 - 763 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8XLOA 2.36 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1LVQ Type1.5_Back 462 - 764 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8XLOB 2.36 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa A1LVQ Type1.5_Back 458 - 763 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8XZ7B 1.75 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1LWW Type1.5_Back 461 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6MZWA 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa TZ0 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5VNDA 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 9ES Type1.5_Back 463 - 765 0 None C488A,Y563C,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5VNDB 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 9ES Type1.5_Back 460 - 765 0 None C488A,Y563C,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6P68A 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa O1Y Type1.5_Back 462 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6P68B 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa O1Y Type1.5_Back 462 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6P68C 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa O1Y Type1.5_Back 463 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6P69A 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa O21 Type1.5_Back 462 - 765 0 None C488A,Y563C Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6P69B 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa O21 Type1.5_Back 461 - 762 0 None C488A,Y563C Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5ZV2A 2.86 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa LEV Type1.5_Back 463 - 762 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5ZV2B 2.86 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-out TYR APEdihe_nioai APEdist_aaaa LEV Type1.5_Back 461 - 764 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4NK9A 2.57 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 2K5 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5B7VB 2.15 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa LWJ Type1.5_Back 462 - 762 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5UR1B 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY9 Type1.5_Back 464 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWLB 2.193 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 3ZC Type1.5_Back 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4F65B 2.26 Inactive DFGin‑None DFGAsp-rot-in in-in none-out TYR APEdihe_iioai APEdist_aaaa 0S9 Type1.5_Back 460 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C18B 2.3 Inactive DFGin‑None DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY5 Type1.5_Back 466 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6MZWB 2.2 Inactive DFGin‑None DFGAsp-rot-none in-in none-none TYR APEdihe_nnnai APEdist_aaaa TZ0 Type1.5_Back 463 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR2 FGFR2_HUMAN 8W3BA 2.23 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W3BB 2.23 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W3BC 2.23 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W3BD 2.23 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 465 - 764 0 None D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W3DA 2.04 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None N549K,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W3DB 2.04 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 463 - 764 0 None N549K,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W3DC 2.04 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 766 0 None N549K,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W3DD 2.04 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 463 - 765 0 None N549K,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6AGXA 2.95 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa 9WX Type1.5_Back 467 - 764 0 PTR586,PTR588,PTR656,PTR657 A628T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6AGXB 2.95 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa 9WX Type1.5_Back 467 - 764 0 PTR586,PTR588,PTR656,PTR657 A628T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6AGXC 2.95 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa 9WX Type1.5_Back 467 - 764 0 PTR586,PTR588,PTR656,PTR657 A628T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6AGXD 2.95 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa 9WX Type1.5_Back 467 - 764 0 PTR586,PTR588,PTR656,PTR657 A628T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 3RI1A 2.1 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 3RH Type1.5_Back 468 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W38A 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None N549D,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W38B 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None N549D,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W38C 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 465 - 764 0 None N549D,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W38D 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None N549D,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W2XA 2.98 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1AFR Type1.5_Back 458 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W2XB 2.98 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1AFR Type1.5_Back 458 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8U1FA 3.33 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-none TYR APEdihe_niiai APEdist_aaaa UIM Type1.5_Back 460 - 764 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8U1FB 3.33 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa UIM Type1.5_Back 472 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8STGB 3.79 Inactive DFGin‑None DFGAsp-rot-in in-out none-out TYR APEdihe_oiiai APEdist_aaaa WCJ Type1.5_Back 472 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 9U3NB 3.25 Inactive DFGin‑None DFGAsp-rot-out in-in none-in TYR APEdihe_iiiai APEdist_aaaa A1ENT Type1.5_Back 470 - 764 0 None V564F Fibroblast growth factor receptor 2
TYR FGFR3 FGFR3_HUMAN 6LVMA 2.53 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa EVR Type1.5_Back 472 - 755 0 PTR577,PTR647,PTR648 None Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 7DHLA 2.57 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa H6X Type1.5_Back 472 - 755 0 PTR577,PTR647,PTR648 None Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDVA 2.348 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa WIQ Type1.5_Back 458 - 755 0 None V555M Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDVB 2.348 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa WIQ Type1.5_Back 455 - 755 0 None V555M Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDVC 2.348 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa WIQ Type1.5_Back 458 - 755 0 None V555M Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDUA 1.737 Inactive DFGin‑BLBplus DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa WIQ Type1.5_Back 460 - 756 0 None P572S,P573G Fibroblast growth factor receptor 3
TYR FGFR4 FGFR4_HUMAN 4XCUA 1.71 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 40M Type1.5_Back 453 - 751 0 None L449M Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6NVGA 1.99 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL8 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6NVHA 1.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-none TYR APEdihe_nniai APEdist_aaaa XL6 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6NVIA 2.117 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-none TYR APEdihe_nniai APEdist_aaaa XL7 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6NVJA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL5 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6NVKA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL9 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6V9CA 1.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa QS7 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7DTZA 2.01 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa HHL Type1.5_Back 453 - 751 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6JPEA 1.601 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa BYU Type1.5_Back 452 - 751 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 5NWZB 2.37 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_niiai APEdist_aaaa 9CT Type1.5_Back 454 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7F3MA 2.289 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa GX3 Type1.5_Back 453 - 753 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7V29A 1.983 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5JR Type1.5_Back 454 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7V29B 1.983 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5JR Type1.5_Back 454 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8XLQA 1.95 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa A1LVQ Type1.5_Back 453 - 751 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4QQCA 2.4 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa 37O Type1.5_Back 445 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 5NWZA 2.37 Inactive DFGin‑BLBplus DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa 9CT Type1.5_Back 454 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4QQ5A 2.203 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa 37O Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4R6VA 2.353 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa FI3 Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4
TYR FGR FGR_HUMAN 7UY0A 2.55 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa VSE Type1.5_Back 80 - 527 0 PTR523 Q524E,P525E,G526I,D527P Tyrosine-protein kinase Fgr
TYR FGR FGR_HUMAN 7UY0B 2.55 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa VSE Type1.5_Back 80 - 527 0 PTR523 Q524E,P525E,G526I,D527P Tyrosine-protein kinase Fgr
TYR HCK HCK_HUMAN 2HK5A 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1BM Type1.5_Back 247 - 514 0 None None Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5ZJ6B 1.696 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa VSE Type1.5_Back 249 - 518 0 None None Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 9BYJA 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa VSE Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VRYA 2.481 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa B43 Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VRYB 2.481 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa B43 Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS3A 2.17 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VSE Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS3B 2.17 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa VSE Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS4A 2.747 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VSF Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS4B 2.747 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VSF Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS6A 2.373 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VSH Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS6B 2.373 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VSH Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 4LUEA 3.04 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VSE Type1.5_Back 81 - 525 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 4LUEB 3.04 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VSE Type1.5_Back 81 - 525 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5H09A 1.945 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa OOO Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5H0BA 1.651 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa OOQ Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5H0EA 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa OOS Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5H0HA 1.72 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa OOV Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS1A 2.464 Inactive DFGin‑None DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VSA Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR JAK2-2 JAK2_HUMAN 5TQ4A 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GY Type1.5_Back 841 - 1132 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ5A 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GX Type1.5_Back 841 - 1131 0 None M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ8A 1.59 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GS Type1.5_Back 841 - 1131 0 None M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7Q7IA 1.78 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9I8 Type1.5_Back 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7Q7KA 1.61 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9I5 Type1.5_Back 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7Q7LA 1.97 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9I2 Type1.5_Back 843 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7Q7WA 1.85 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9HR Type1.5_Back 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3JY9A 2.1 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa JZH Type1.5_Back 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3KCKA 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 3KC Type1.5_Back 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ3A 2.69 Inactive DFGin‑None DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GZ Type1.5_Back 843 - 1132 0 PTR1007,PTR1008 M1073S,F1076T,I1126V Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ3B 2.69 Inactive DFGin‑None DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GZ Type1.5_Back 843 - 1132 0 PTR1007,PTR1008 M1073S,F1076T,I1126V Tyrosine-protein kinase JAK2
TYR KDR VGFR2_HUMAN 2XIRA 1.5 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 00J Type1.5_Back 816 - 1168 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 4AGCA 2.0 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa AXI Type1.5_Back 801 - 1169 0 None E990V Vascular endothelial growth factor receptor 2
TYR KIT KIT_HUMAN 7KHKB 2.34 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa WEJ Type1.5_Back 567 - 929 0 None None Mast/stem cell growth factor receptor Kit
TYR LCK LCK_HUMAN 3BYMA 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa AM0 Type1.5_Back 230 - 501 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3KMMA 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa LHL Type1.5_Back 231 - 501 0 PTR394 Y505F Tyrosine-protein kinase Lck
TYR LYN LYN_HUMAN 5XY1A 2.7 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 8H0 Type1.5_Back 239 - 502 0 None None Tyrosine-protein kinase Lyn
TYR MERTK MERTK_HUMAN 6MEPA 2.893 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa 9VS Type1.5_Back 576 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 6MEPB 2.893 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 9VS Type1.5_Back 578 - 862 0 None None Tyrosine-protein kinase Mer
TYR NTRK1 NTRK1_HUMAN 4PMSA 2.8 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 31X Type1.5_Back 501 - 787 0 None None High affinity nerve growth factor receptor
TYR RET RET_HUMAN 6NECA 1.87 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa XIN Type1.5_Back 713 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 6NECC 1.87 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa XIN Type1.5_Back 705 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7DUAA 1.64 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa HJ0 Type1.5_Back 712 - 1011 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7DUAB 1.64 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa HJ0 Type1.5_Back 705 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7RUNA 3.51 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa 7QU Type1.5_Back 705 - 1012 0 PTR809,PTR905,SEP909,PTR928 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7RUNB 3.51 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa 7QU Type1.5_Back 706 - 1012 0 PTR809,PTR905,SEP909,PTR928 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR SRC SRC_HUMAN 6E6EB 2.15 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa HVY Type1.5_Back 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 6E6EE 2.15 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_ooiai APEdist_aaaa HVY Type1.5_Back 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 6E6EG 2.15 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa HVY Type1.5_Back 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 7NG7A 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa UCW Type1.5_Back 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR TNK2 ACK1_HUMAN 4ID7A 3.0 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa 1G0 Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 8HMTA 3.17 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 8HMTB 3.17 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa LWX Type1.5_Back 117 - 388 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 8HMTC 3.17 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 3EQRA 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa T74 Type1.5_Back 117 - 392 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 3EQRB 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa T74 Type1.5_Back 117 - 390 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 8HMTD 3.17 Inactive DFGin‑None DFGAsp-rot-out in-out in-in TYR APEdihe_iiiai APEdist_aaaa LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1
TYR TYK2-2 TYK2_HUMAN 3NYXA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa TZ1 Type1.5_Back 889 - 1176 0 None D1023N Non-receptor tyrosine-protein kinase TYK2

All / All / Type1.5_Back

Total number of chains: 646
Active chains: 105
Total number of genes: 88
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 295 45.7% 6RCHA
DFGin BLBplus 124 19.2% 5P9IA
DFGin BLAplus 116 18.0% 6JUUA
DFGin None 40 6.2% 7SIUA
DFGin BLBminus 25 3.9% 5RA7A
DFGin ABAminus 19 2.9% 5UU1A
DFGout None 11 1.7% 1OPKA
DFGout BBAminus 7 1.1% 2XIRA
None None 5 0.8% 3V51A
DFGin BLBtrans 2 0.3% 9GC5A
DFGinter None 2 0.3% 4ZTSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AGC PRKACA KAPCA_BOVIN 3E8CA 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 8 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8CB 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 5 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8CC 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 8 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8CD 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 5 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8CE 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 14 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8CF 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 8 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8EA 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 8 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8EB 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 13 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8EE 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 8 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8EI 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 4 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8EL 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 14 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8EP 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 8 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 4C35A 2.19 Inactive DFGin‑None DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NU3 Type1.5_Back 11 - 351 0 SEP11,SEP140,TPO198,SEP339 F55Y,M121L,V124L,L174M,Q182K cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
TYR SRC SRC_CHICK 3QLGA 2.75 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa 1N1 Type1.5_Back 258 - 533 0 None L317I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3QLGB 2.75 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa 1N1 Type1.5_Back 256 - 533 0 None L317I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3EN4B 2.55 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa KS1 Type1.5_Back 257 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3UQFA 2.27 Inactive DFGin‑BLAminus DFGAsp-rot-out in-none none-none TYR APEdihe_nnnai APEdist_aaaa BK5 Type1.5_Back 258 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4DGGB 2.65 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa I76 Type1.5_Back 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 6WIWB 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nnnai APEdist_aaaa I14 Type1.5_Back 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 7D57B 2.104 Inactive DFGin‑BLAminus DFGAsp-rot-none in-out in-none TYR APEdihe_nniai APEdist_aaaa 37O Type1.5_Back 257 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3G5DA 2.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 1N1 Type1.5_Back 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3G5DB 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa 1N1 Type1.5_Back 258 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3SVVA 2.204 Inactive DFGin‑BLBminus DFGAsp-rot-out in-in out-none TYR APEdihe_nnnai APEdist_aaaa VSP Type1.5_Back 257 - 533 0 None T338C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3SVVB 2.204 Inactive DFGin‑BLBminus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa VSP Type1.5_Back 256 - 533 0 None T338C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4YBKA 2.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 4B7 Type1.5_Back 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5TEHA 2.99 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa S56 Type1.5_Back 256 - 533 0 None V281C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 6WIWA 2.3 Inactive None‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nnnai APEdist_aaaa I14 Type1.5_Back 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
AGC AKT2 AKT2_HUMAN 3D0EA 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G93 Type1.5_Back 146 - 480 0 TPO309,TPO451 None RAC-beta serine/threonine-protein kinase Homo sapiens
AGC AKT2 AKT2_HUMAN 3D0EB 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G93 Type1.5_Back 146 - 480 0 TPO309,TPO451 None RAC-beta serine/threonine-protein kinase Homo sapiens
AGC AKT2 AKT2_HUMAN 3E88A 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 146 - 480 0 TPO309,TPO451 S474D RAC-beta serine/threonine-protein kinase Homo sapiens
AGC AKT2 AKT2_HUMAN 3E88B 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 146 - 480 0 TPO309,TPO451 S474D RAC-beta serine/threonine-protein kinase Homo sapiens
AGC AKT2 AKT2_HUMAN 3E8DA 2.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 146 - 480 0 TPO309,TPO451 S474D RAC-beta serine/threonine-protein kinase Homo sapiens
AGC AKT2 AKT2_HUMAN 3E8DB 2.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 146 - 480 0 TPO309,TPO451 S474D RAC-beta serine/threonine-protein kinase Homo sapiens
AGC PDPK1 PDPK1_HUMAN 3QCXA 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 3Q2 Type1.5_Back 73 - 358 0 SEP241 None 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 3TWJA 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaoii APEdist_iioo 07R Type1.5_Back 7 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
CAMK AURKA AURKA_HUMAN 4ZTQA 2.8 Inactive DFGinter‑None DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 4RM Type1.5_Back 127 - 388 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 4ZTSA 2.9 Inactive DFGinter‑None DFGAsp-rot-out out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 4RK Type1.5_Back 127 - 388 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 2C6EA 2.1 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno HPM Type1.5_Back 127 - 389 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 3W2CA 2.45 Inactive None‑None DFGAsp-rot-out out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn N15 Type1.5_Back 128 - 388 0 None None Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 3W2CG 2.45 Inactive None‑None DFGAsp-rot-out out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn N15 Type1.5_Back 128 - 388 0 None None Aurora kinase A Homo sapiens
CAMK CAMK2A KCC2A_HUMAN 6X5GA 1.85 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BCN Type1.5_Back 7 - 274 0 None D135N,Q223K Calcium/calmodulin-dependent protein kinase type II subunit alpha Homo sapiens
CAMK CAMKK2 KKCC2_HUMAN 5YV9A 2.53 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 91O Type1.5_Back 160 - 448 0 None None Calcium/calmodulin-dependent protein kinase kinase 2 Homo sapiens
CAMK CHEK1 CHK1_HUMAN 2E9NA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 76A Type1.5_Back 2 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CAMK CHEK1 CHK1_HUMAN 4FSTA 1.9 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK4 Type1.5_Back 3 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CAMK CHEK1 CHK1_HUMAN 2AYPA 2.9 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 43A Type1.5_Back 2 - 269 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CAMK CHEK1 CHK1_HUMAN 4FSQA 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HK3 Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CAMK CHEK1 CHK1_HUMAN 4FTKA 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H9K Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CAMK CHEK1 CHK1_HUMAN 4FTLA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in nonTYR APEdihe_aaiii APEdist_iiii H0K Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CAMK CHEK1 CHK1_HUMAN 4FTMA 1.9 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1HK Type1.5_Back 3 - 280 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CAMK CHEK1 CHK1_HUMAN 4FTNA 2.02 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2HK Type1.5_Back 3 - 271 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CAMK CHEK1 CHK1_HUMAN 2C3KA 2.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ABO Type1.5_Back 6 - 270 0 None None Serine/threonine-protein kinase Chk1 Homo sapiens
CAMK CHEK2 CHK2_HUMAN 2YITA 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_oooo YIT Type1.5_Back 211 - 510 0 None None Serine/threonine-protein kinase Chk2 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 5AUUA 1.7 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LU2 Type1.5_Back 2 - 277 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 5AUWA 1.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out nonTYR APEdihe_aaiii APEdist_iooi QUE Type1.5_Back 2 - 277 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 5AUYA 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out nonTYR APEdihe_aaiii APEdist_iooi MRI Type1.5_Back 2 - 277 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 7CCUA 1.649 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-out nonTYR APEdihe_aaiii APEdist_iooi STL Type1.5_Back 2 - 277 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 7CCVA 1.753 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out nonTYR APEdihe_aaiii APEdist_iooi PIT Type1.5_Back 2 - 277 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 8IE5A 1.803 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi EZE Type1.5_Back 2 - 277 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK MELK MELK_HUMAN 5TVTA 2.28 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_nnni 7LV Type1.5_Back 2 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 5TWLA 2.42 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in none-out nonTYR APEdihe_aaioi APEdist_nnni H91 Type1.5_Back 2 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 5MAFA 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn XIN Type1.5_Back 2 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4D2PA 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4D2PB 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnii 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4D2PC 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4D2PD 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4UMPA 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4UMPB 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaini APEdist_nnoi 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4UMPC 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 4UMQA 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaoii APEdist_nnoo B5S Type1.5_Back 5 - 333 0 None T167A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
CAMK PIM1 PIM1_HUMAN 3T9IA 2.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3T9 Type1.5_Back 33 - 306 0 SEP261 None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PIM1 PIM1_HUMAN 6AYDA 3.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii C2J Type1.5_Back 34 - 305 0 None R250G Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK STK17B ST17B_HUMAN 3LM5A 2.29 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-out nonTYR APEdihe_aaiii APEdist_nnoo QUE Type1.5_Back 25 - 301 0 None None Serine/threonine-protein kinase 17B Homo sapiens
CK1 CSNK1D KC1D_HUMAN 6RCHA 1.45 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii K0B Type1.5_Back 2 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 6RU7A 2.08 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 3 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 6RU7B 2.08 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 3 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 6RU8A 1.92 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 2 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 6RU8B 1.92 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 2 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 6RU8C 1.92 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 2 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 6RU8D 1.92 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 2 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1G3 KC1G3_HUMAN 4HGSA 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iioi 15G Type1.5_Back 34 - 334 0 None None Casein kinase I isoform gamma-3 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 7ZHNA 1.85 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VP7 Type1.5_Back 21 - 313 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 7ZHOA 2.08 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQR Type1.5_Back 21 - 317 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 7ZHPA 1.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQY Type1.5_Back 21 - 313 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 7ZHQA 1.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IRD Type1.5_Back 21 - 313 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 7JXXA 1.56 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VP7 Type1.5_Back 22 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 7JXYA 2.15 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii VSY Type1.5_Back 23 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 7JXYB 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_iini VSY Type1.5_Back 20 - 312 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 TTBK1 TTBK1_HUMAN 4BTKA 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iiii DTQ Type1.5_Back 22 - 311 0 None None Tau-tubulin kinase 1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 5UVFC 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oioi 7DZ Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 5UVFD 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 7DZ Type1.5_Back 25 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6BP0D 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii E1D Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6BRUB 1.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oooi E5M Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6BRUD 1.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oioi E5M Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6BTWA 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi E8D Type1.5_Back 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6BTWD 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii E8D Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6BU6A 1.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi E8V Type1.5_Back 20 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6CFMA 2.45 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi EA7 Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6CFMB 2.45 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EA7 Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6CFMD 2.45 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii EA7 Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6CNXB 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F87 Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6CNXC 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_nooi FCS Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6CNXD 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F87 Type1.5_Back 24 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6NPNA 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi KWJ Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6NPNB 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii KWJ Type1.5_Back 24 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6NPNC 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi KWJ Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6NPND 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii KWJ Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6VXUC 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi VBD Type1.5_Back 21 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6VZHB 2.55 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oioi RYA Type1.5_Back 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6VZHD 2.55 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii RYA Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 9ZKGC 2.06 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii A1C2O Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 9ZKGD 2.06 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_oiii A1C2O Type1.5_Back 22 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK2 VRK2_HUMAN 5UU1A 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 7DZ Type1.5_Back 14 - 328 0 None None Serine/threonine-protein kinase VRK2 Homo sapiens
CK1 VRK2 VRK2_HUMAN 6NCGA 2.45 Inactive DFGin‑BLAminus DFGAsp-rot-in in-none in-out nonTYR APEdihe_aaiii APEdist_iooi KJD Type1.5_Back 14 - 326 0 None None Serine/threonine-protein kinase VRK2 Homo sapiens
CK1 VRK2 VRK2_HUMAN 6NCGB 2.45 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none nonTYR APEdihe_aaiii APEdist_nnii KJD Type1.5_Back 16 - 326 0 None None Serine/threonine-protein kinase VRK2 Homo sapiens
CK1 VRK2 VRK2_HUMAN 9FETA 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii REB Type1.5_Back 15 - 330 0 None None Serine/threonine-protein kinase VRK2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3F5XA 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iioi EZV Type1.5_Back 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3F5XC 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iiii EZV Type1.5_Back 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3BHUC 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii MHR Type1.5_Back 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK9 CDK9_HUMAN 4IMYA 2.94 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP Type1.5_Back 8 - 330 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 6L22A 2.123 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iiii E3U Type1.5_Back 2 - 335 0 None H115Y Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 5OWHA 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-in nonTYR APEdihe_aaiii APEdist_iiii B0K Type1.5_Back 2 - 335 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 7BU4A 1.702 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iiii Y49 Type1.5_Back 2 - 335 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 6L21A 2.055 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iiii E3U Type1.5_Back 2 - 332 0 None H160A Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 7I84A 1.97 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1BZY Type1.5_Back 3 - 329 0 None R21S,K74A,K75A,K76A Casein kinase II subunit alpha Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 8C3QA 2.32 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RUT Type1.5_Back 134 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 8C3QB 2.32 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RUT Type1.5_Back 136 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC GSK3B GSK3B_HUMAN 5OY4A 3.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4K Type1.5_Back 36 - 385 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 5OY4B 3.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4K Type1.5_Back 30 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 4IQ6B 3.12 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQ6 Type1.5_Back 37 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC MAPK10 MK10_HUMAN 2O0UA 2.1 Inactive DFGin‑ABAminus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaiii APEdist_oooo C0M Type1.5_Back 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK14 MK14_HUMAN 6TCAB 3.7 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaioi APEdist_iiii 39G Type1.5_Back 6 - 354 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 6TCAD 3.7 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaooi APEdist_iioi 39G Type1.5_Back 4 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 6TCAF 3.7 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaioi APEdist_iioi 39G Type1.5_Back 6 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 6TCAH 3.7 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 39G Type1.5_Back 4 - 353 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2ZB1A 2.5 Inactive DFGin‑BLBminus DFGAsp-rot-out in-in none-out nonTYR APEdihe_aaooi APEdist_oooo GK4 Type1.5_Back 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 5XYXA 2.61 Inactive DFGin‑BLBminus DFGAsp-rot-out in-in none-out nonTYR APEdihe_aaooi APEdist_nnno FTZ Type1.5_Back 4 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 5XYYA 1.7 Inactive DFGin‑BLBminus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aaooi APEdist_oooo P0F Type1.5_Back 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2RG5A 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 279 Type1.5_Back 4 - 351 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3BX5A 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-none nonTYR APEdihe_aanii APEdist_nnnn 304 Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3L8XA 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aaooi APEdist_nnno N4D Type1.5_Back 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 5OMHA 2.5 Inactive None‑None DFGAsp-rot-out in-out none-out nonTYR APEdihe_aaooi APEdist_nnno 9Y5 Type1.5_Back 5 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4G31A 2.28 Inactive DFGin‑None DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 0WH Type1.5_Back 588 - 1080 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4G34A 2.7 Inactive DFGin‑None DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 924 Type1.5_Back 588 - 1079 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4M7IA 2.34 Inactive DFGin‑None DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 27D Type1.5_Back 588 - 1080 0 None None Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 8EQEAAA 2.559 Inactive DFGin‑None DFGAsp-rot-in out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn WQ2 Type1.5_Back 585 - 1080 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3OA 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-out out-out out-none nonTYR APEdihe_aanai APEdist_nnnn KA7 Type1.5_Back 584 - 1004 0 None K807A,D848N,T899E,T904E eIF-2-alpha kinase GCN2 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6W3EB 2.737 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaooi APEdist_nnoo SJV Type1.5_Back 563 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6XDFA 2.54 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_iooi N94 Type1.5_Back 560 - 966 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 7BMKA 1.85 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_iooi U4N Type1.5_Back 561 - 966 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 7BMKB 1.85 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_ioio U4N Type1.5_Back 562 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6URCA 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_iooi QFV Type1.5_Back 560 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6URCB 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_iooi QFV Type1.5_Back 560 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6XDDB 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in nonTYR APEdihe_aaiii APEdist_iiii N97 Type1.5_Back 560 - 963 0 SEP724,SEP726,SEP729 None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4U6RA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_iioi 3E4 Type1.5_Back 561 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 6XDBA 2.45 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaiii APEdist_iooi N8S Type1.5_Back 561 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER GAK GAK_HUMAN 4C58A 2.16 Inactive DFGin‑ABAminus DFGAsp-rot-out in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 824 Type1.5_Back 27 - 333 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER HASPIN HASP_HUMAN 6Z56A 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q7Q Type1.5_Back 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 6Z5BA 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q7Z Type1.5_Back 469 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER HASPIN HASP_HUMAN 9FLCA 2.18 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDA Type1.5_Back 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9LGVA 2.041 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJV Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9LIDA 2.06 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJX Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9LIDB 2.06 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJX Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9LGNA 2.03 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJU Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9LGNB 2.03 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi A1EJU Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8D6DA 2.35 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGY Type1.5_Back 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8D6EA 2.15 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QGI Type1.5_Back 77 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8D6FA 2.49 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QG5 Type1.5_Back 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 8D6FB 2.49 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiai APEdist_iooi QG5 Type1.5_Back 76 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER PKMYT1 PMYT1_HUMAN 9M6PBBB 2.383 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiai APEdist_iiii A1EMX Type1.5_Back 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER TTK TTK_HUMAN 6TNDA 2.58 Inactive DFGin‑ABAminus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 8RH Type1.5_Back 516 - 793 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3W1FA 2.7 Inactive DFGin‑ABAminus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 1O5 Type1.5_Back 516 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3WZJA 2.75 Inactive DFGin‑ABAminus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aaioi APEdist_nnno O43 Type1.5_Back 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 3WZKA 2.3 Inactive DFGin‑ABAminus DFGAsp-rot-out in-in out-out nonTYR APEdihe_aaioi APEdist_nnno O23 Type1.5_Back 516 - 794 0 None None Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5NADA 2.8 Inactive DFGin‑ABAminus DFGAsp-rot-out in-in out-none nonTYR APEdihe_aanni APEdist_nnnn 8RH Type1.5_Back 519 - 794 0 TPO686 None Dual specificity protein kinase TTK Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7XLPA 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaioi APEdist_nnno FZC Type1.5_Back 37 - 382 0 None S298N,S299K,Y300K Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K7 MP2K7_HUMAN 7OVKA 2.05 Inactive DFGin‑None DFGAsp-rot-in na-na none-none nonTYR APEdihe_aannn APEdist_nnnn 2I5 Type1.5_Back 102 - 401 0 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
STE MAP3K14 M3K14_HUMAN 4IDVA 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 13V Type1.5_Back 331 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Homo sapiens
STE MAP3K14 M3K14_HUMAN 4IDVB 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 13V Type1.5_Back 331 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Homo sapiens
STE MAP3K14 M3K14_HUMAN 4IDVC 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 13V Type1.5_Back 331 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Homo sapiens
STE MAP3K14 M3K14_HUMAN 4IDVD 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 13V Type1.5_Back 331 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Homo sapiens
STE MAP4K1 M4K1_HUMAN 9BJ1B 2.18 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in out-out nonTYR APEdihe_aaioi APEdist_oooo A1APQ Type1.5_Back 5 - 293 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 7SIUA 1.786 Inactive DFGin‑None DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaioi APEdist_oioo 9ID Type1.5_Back 5 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 7SIUB 1.786 Inactive DFGin‑None DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 9ID Type1.5_Back 16 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K4 M4K4_HUMAN 5W5QA 2.33 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 9X4 Type1.5_Back 17 - 311 0 None None Mitogen-activated protein kinase kinase kinase kinase 4 Homo sapiens
STE PAK1 PAK1_HUMAN 4EQCA 2.01 Inactive DFGin‑BLAminus DFGAsp-rot-out out-none in-in nonTYR APEdihe_aaiii APEdist_iiii XR1 Type1.5_Back 249 - 541 0 TPO423 K299R Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 5DEYA 2.1 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 59T Type1.5_Back 250 - 544 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4O0TA 2.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2OL Type1.5_Back 251 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 5IMEA 2.217 Inactive DFGin‑BLAminus DFGAsp-rot-out out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6BZ Type1.5_Back 251 - 545 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 9N4UA 1.77 Inactive DFGin‑BLAminus DFGAsp-rot-out out-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BV8 Type1.5_Back 249 - 545 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK4 PAK4_HUMAN 7CP3A 2.9 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GC6 Type1.5_Back 300 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 7CP4A 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GCC Type1.5_Back 300 - 591 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 7CMBA 2.592 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G5X Type1.5_Back 300 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 4O0VA 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2OL Type1.5_Back 300 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 4O0XA 2.483 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2OQ Type1.5_Back 300 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE PAK4 PAK4_HUMAN 4O0YA 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2OO Type1.5_Back 300 - 589 0 SEP474 None Serine/threonine-protein kinase PAK 4 Homo sapiens
STE STK24 STK24_HUMAN 4QMWA 1.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KS1 Type1.5_Back 24 - 310 0 TPO190 None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 8BZIA 1.72 Inactive DFGin‑BLBminus DFGAsp-rot-out out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SJL Type1.5_Back 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 8BZJA 2.52 Inactive DFGin‑BLBminus DFGAsp-rot-out out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SJX Type1.5_Back 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK26 STK26_HUMAN 7B36C 2.107 Inactive DFGin‑BLBminus DFGAsp-rot-out out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 59T Type1.5_Back 17 - 299 0 None None Serine/threonine-protein kinase 26 Homo sapiens
STE TNIK TNIK_HUMAN 8ZMLA 2.489 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1D8H Type1.5_Back 11 - 312 0 TPO181,TPO187 None TRAF2 and NCK-interacting protein kinase Homo sapiens
TKL BRAF BRAF_HUMAN 3PPJA 3.7 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_nnno FOI Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3PPJB 3.7 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_nioo FOI Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7SHVB 2.88 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_nnio 29L Type1.5_Back 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4CQEA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaoii APEdist_nnno CQE Type1.5_Back 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JRQA 2.287 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 6N9 Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JRQB 2.287 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 6N9 Type1.5_Back 448 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JSMB 2.19 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 6NB Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JSMC 2.19 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NB Type1.5_Back 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JT2A 2.702 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NC Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5JT2C 2.702 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 6NC Type1.5_Back 448 - 719 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4RZVA 2.994 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaiii APEdist_nioo 032 Type1.5_Back 449 - 721 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4RZVB 2.994 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaiii APEdist_iioo 032 Type1.5_Back 449 - 722 0 None R509H,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV1A 2.47 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 904 Type1.5_Back 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV3A 2.8 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno P02 Type1.5_Back 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4FK3A 2.65 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 325 Type1.5_Back 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6UUOB 3.288 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaooi APEdist_nnno QH1 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5ITAA 1.95 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 6DC Type1.5_Back 448 - 718 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4WO5A 2.83 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaooo APEdist_iooo 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4WO5B 2.83 Inactive DFGin‑BLAplus DFGAsp-rot-in out-none out-out nonTYR APEdihe_aaiii APEdist_nnno 324 Type1.5_Back 450 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3OG7A 2.45 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 032 Type1.5_Back 449 - 720 0 None K522A,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4EHGA 3.5 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaioi APEdist_nnno RI9 Type1.5_Back 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4EHGB 3.5 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo RI9 Type1.5_Back 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5FD2A 2.89 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 5XJ Type1.5_Back 448 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3TV4A 3.4 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo TV4 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3TV4B 3.4 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_iooo TV4 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3TV6A 3.3 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo B0R Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3TV6B 3.3 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_iooo B0R Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4E4XA 3.6 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_nooo T1Q Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4E4XB 3.6 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_iooo T1Q Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4EHEA 3.3 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo RI8 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4EHEB 3.3 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_iooo RI8 Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4PP7A 3.4 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaoii APEdist_nooo 2VX Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4PP7B 3.4 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_iooo 2VX Type1.5_Back 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8VYSA 3.06 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1AEN Type1.5_Back 235 - 738 0 SEP365,SEP729 V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7P3VA 2.37 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 5I4 Type1.5_Back 448 - 719 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7P3VB 2.37 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_oooo 5I4 Type1.5_Back 448 - 719 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4CQEB 2.3 Inactive DFGin‑BLBminus DFGAsp-rot-in in-out none-out nonTYR APEdihe_aaoii APEdist_nnno CQE Type1.5_Back 448 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV2A 2.5 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno P06 Type1.5_Back 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV2B 2.5 Inactive DFGin‑BLBminus DFGAsp-rot-in in-out none-out nonTYR APEdihe_aaoii APEdist_nnno P06 Type1.5_Back 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5CSWB 2.66 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out none-none nonTYR APEdihe_aanii APEdist_nnnn P06 Type1.5_Back 447 - 721 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6V2UB 3.78 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out none-none nonTYR APEdihe_aanii APEdist_nnnn P06 Type1.5_Back 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3C4CA 2.57 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5CSWA 2.66 Inactive DFGin‑None DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaoii APEdist_nnno P06 Type1.5_Back 449 - 721 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5ITAB 1.95 Inactive DFGin‑None DFGAsp-rot-in out-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6DC Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6V2UA 3.78 Inactive DFGin‑None DFGAsp-rot-in out-none none-out nonTYR APEdihe_aaiii APEdist_nnno P06 Type1.5_Back 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4MBJA 3.6 Inactive DFGin‑None DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaioi APEdist_nooo DFS Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4MBJB 3.6 Inactive DFGin‑None DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaioi APEdist_iooo DFS Type1.5_Back 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5CSXA 2.51 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 54J Type1.5_Back 448 - 720 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3C4CB 2.57 Inactive DFGout‑None DFGAsp-rot-in in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 324 Type1.5_Back 448 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL IRAK4 IRAK4_HUMAN 5T1SB 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 76Q Type1.5_Back 161 - 459 0 TPO342,TPO345,SEP346 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL KSR2 KSR2_HUMAN 5KKRB 3.509 Pseudo DFGin‑BLBplus DFGAsp-rot-in out-none out-out nonTYR APEdihe_aaoai APEdist_oooo 6U7 Type1.5_Back 650 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7ATSA 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none none-none nonTYR APEdihe_aannn APEdist_nnnn RXQ Type1.5_Back 330 - 634 0 None None LIM domain kinase 1 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 5HESA 2.14 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 032 Type1.5_Back 6 - 299 0 TPO161 None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 5X5OA 1.868 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaoii APEdist_oioo 7Z0 Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 6JUTA 2.1 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_iioo C9O Type1.5_Back 8 - 304 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 6JUUA 1.903 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_oioo C9R Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 7YAWA 2.1 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_oioo IGS Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 7YAWD 2.1 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaooi APEdist_oooo IGS Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL MAP3K20 M3K20_HUMAN 7YAZA 2.54 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-out nonTYR APEdihe_aaoii APEdist_oioo IGV Type1.5_Back 8 - 299 0 None None Mitogen-activated protein kinase kinase kinase 20 Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0UE 2.91 Inactive DFGin‑BLAplus DFGAsp-rot-in out-none none-out nonTYR APEdihe_aaioi APEdist_nnno 324 Type1.5_Back 339 - 613 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0VE 3.5 Inactive DFGin‑BLAplus DFGAsp-rot-in out-none none-out nonTYR APEdihe_aaioi APEdist_iioo 324 Type1.5_Back 339 - 613 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0UA 2.91 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none out-out nonTYR APEdihe_aaioi APEdist_oooo 324 Type1.5_Back 339 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0VA 3.5 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none out-out nonTYR APEdihe_aaioi APEdist_oioo 324 Type1.5_Back 339 - 612 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6UL8A 2.68 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_nnno Q9J Type1.5_Back 5 - 310 0 None C7S,S168C Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6UL8B 2.68 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_nnno Q9J Type1.5_Back 5 - 310 0 None C7S,S168C Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6RN8A 2.69 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out nonTYR APEdihe_aaioi APEdist_nnno K9T Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6RN8B 2.69 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out nonTYR APEdihe_aaioi APEdist_nioo K9T Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6RNAA 2.62 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo KA2 Type1.5_Back 5 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6RNAB 2.62 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out nonTYR APEdihe_aaioi APEdist_nioo KA2 Type1.5_Back 4 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 8X2OA 2.26 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaoni APEdist_nnno 6IL Type1.5_Back 8 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 8X2OB 2.26 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out nonTYR APEdihe_aaooi APEdist_nnno 6IL Type1.5_Back 9 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR8B 2.79 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo XYW Type1.5_Back 8 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR8A 2.79 Inactive DFGin‑None DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioi APEdist_nnno XYW Type1.5_Back 9 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 7MX3A 3.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ZOV Type1.5_Back 12 - 314 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 7MX3C 3.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ZOV Type1.5_Back 9 - 311 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 7MX3D 3.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn ZOV Type1.5_Back 12 - 311 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 9LFUA 2.93 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none nonTYR APEdihe_aanii APEdist_nnnn A1D97 Type1.5_Back 5 - 308 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL RIPK3 RIPK3_HUMAN 9LFUB 2.93 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1D97 Type1.5_Back 5 - 309 0 None C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 4X2JA 1.69 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3WN Type1.5_Back 200 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 4X2KA 1.69 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3WO Type1.5_Back 200 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 5QIMA 1.75 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J2Y Type1.5_Back 200 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 6B8YA 1.65 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii D0A Type1.5_Back 200 - 502 0 None T204D TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 2X7OC 3.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 2X7OD 3.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 2X7OE 3.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZOP Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3KCFA 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3KCFB 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3KCFC 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3KCFD 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3KCFE 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii JZO Type1.5_Back 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2GQGB 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1N1 Type1.5_Back 229 - 499 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 8I7TA 2.8 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa 6I5 Type1.5_Back 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2HZIB 1.7 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa JIN Type1.5_Back 233 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2G2HB 2.0 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa P16 Type1.5_Back 233 - 504 0 None H396P Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2FO0A 2.27 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa P16 Type1.5_Back 46 - 511 0 SEP50 D363N Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 1OPLA 3.42 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa P16 Type1.5_Back 62 - 512 0 None K12R,D363N Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 1OPLB 3.42 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa P16 Type1.5_Back 121 - 499 0 None K12R,D363N Tyrosine-protein kinase ABL1 Homo sapiens
TYR BTK BTK_HUMAN 6J6MA 1.25 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa BA0 Type1.5_Back 393 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7R61A 1.52 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 2IJ Type1.5_Back 390 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6DI3A 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa GJA Type1.5_Back 393 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6DI5A 1.42 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa GJ7 Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6N9PA 2.23 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa KHD Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6OMUA 1.41 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa MZJ Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7L5OA 1.21 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa R1L Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7L5PA 2.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa R1L Type1.5_Back 392 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7L5PB 2.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa R1L Type1.5_Back 393 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7R60A 1.94 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 2IE Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8E2MA 1.904 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa UB6 Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6W7OA 2.17 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa TL7 Type1.5_Back 396 - 656 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6W7OB 2.17 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa TL7 Type1.5_Back 396 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6W8IC 3.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa TKY Type1.5_Back 395 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8DSOB 2.334 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_iooai APEdist_aaaa TOO Type1.5_Back 392 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4YHFA 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa 4C9 Type1.5_Back 391 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 4YHFB 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 4C9 Type1.5_Back 390 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5P9IA 1.11 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 1E8 Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5P9JA 1.08 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 8E8 Type1.5_Back 394 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5P9MA 1.41 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 7GB Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 3GENA 1.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa B43 Type1.5_Back 392 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6E4FA 1.15 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa HRA Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 3PJ2A 1.75 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 04K Type1.5_Back 391 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR CSF1R CSF1R_HUMAN 3DPKA 1.95 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa 8C5 Type1.5_Back 548 - 912 0 None None Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8D73A 2.17 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QCR Type1.5_Back 703 - 1011 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8D73B 2.17 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QCR Type1.5_Back 704 - 1012 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8D76A 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QFO Type1.5_Back 703 - 1014 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8D76B 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QFO Type1.5_Back 702 - 1014 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6D8EA 2.537 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa FZP Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9GL9A 2.147 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IMT Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9FRDA 2.06 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IEZ Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9GI9A 3.12 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1ILZ Type1.5_Back 696 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8F1ZA 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa X9B Type1.5_Back 695 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9QXNAAA 2.142 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1JBI Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4RJ5A 3.1 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 3QY Type1.5_Back 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CAQA 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZJ Type1.5_Back 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CASA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZQ Type1.5_Back 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5CAUA 2.25 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZR Type1.5_Back 696 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5HCYA 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 60D Type1.5_Back 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5HICA 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 63N Type1.5_Back 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4R5SA 3.001 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out TYR APEdihe_nnoao APEdist_aaaa FI3 Type1.5_Back 697 - 1018 0 None L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9DF2A 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IMS Type1.5_Back 701 - 1004 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9DF3A 1.68 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IMS Type1.5_Back 701 - 1022 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9DF4A 1.78 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1A4E Type1.5_Back 701 - 1019 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9FQPA 2.495 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IEZ Type1.5_Back 701 - 1020 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9FQSA 1.783 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IE0 Type1.5_Back 701 - 1019 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9GL7A 1.878 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IMS Type1.5_Back 702 - 1019 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9GL8A 1.632 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IMT Type1.5_Back 701 - 1021 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFUB 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out out-none none-none TYR APEdihe_nniai APEdist_aaaa N7K Type1.5_Back 700 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5EDQA 2.8 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 5N3 Type1.5_Back 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5EM6A 2.78 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 5Q3 Type1.5_Back 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5GNKA 1.796 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 80U Type1.5_Back 697 - 985 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WA2A 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa TOV Type1.5_Back 699 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WA2B 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WA2C 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WA2D 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8FV3C 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa YA6 Type1.5_Back 701 - 1009 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8FV4D 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa YAA Type1.5_Back 701 - 1005 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFUA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa N7K Type1.5_Back 700 - 982 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFVA 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none none-none TYR APEdihe_niiai APEdist_aaaa N7Q Type1.5_Back 700 - 985 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFVB 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa N7Q Type1.5_Back 698 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFWA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa N7W Type1.5_Back 700 - 982 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFWB 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa N7W Type1.5_Back 700 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFYB 1.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa N7Z Type1.5_Back 699 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFZA 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none none-none TYR APEdihe_niiai APEdist_aaaa N7B Type1.5_Back 701 - 982 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TFZB 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none out-none TYR APEdihe_nniai APEdist_aaaa N7B Type1.5_Back 700 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TG0A 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa N78 Type1.5_Back 700 - 985 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TG0B 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa N78 Type1.5_Back 698 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TG1A 1.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa N82 Type1.5_Back 699 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6TG1B 1.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none none-none TYR APEdihe_nniai APEdist_aaaa N82 Type1.5_Back 698 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2JIVB 3.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_ooiai APEdist_aaaa HKI Type1.5_Back 699 - 982 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5GTYB 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1.5_Back 700 - 1014 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5GTYD 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1.5_Back 701 - 1014 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5GTYE 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1.5_Back 701 - 1014 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5GTYG 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1.5_Back 699 - 1014 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5GTYH 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1.5_Back 700 - 1016 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3W2RA 2.05 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa W2R Type1.5_Back 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2RGPA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa HYZ Type1.5_Back 702 - 1016 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3BELA 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa POX Type1.5_Back 702 - 1015 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8PO4A 1.621 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 26X Type1.5_Back 700 - 1014 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3LZBA 2.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa ITI Type1.5_Back 703 - 983 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3LZBB 2.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa ITI Type1.5_Back 703 - 983 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3LZBC 2.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa ITI Type1.5_Back 704 - 983 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3LZBD 2.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa ITI Type1.5_Back 703 - 983 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3POZA 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa 03P Type1.5_Back 701 - 1017 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3W2SA 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa W2R Type1.5_Back 701 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3W32A 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa W32 Type1.5_Back 701 - 1017 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3W33A 1.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa W19 Type1.5_Back 701 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 1XKKA 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_nnoai APEdist_aaaa FMM Type1.5_Back 702 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8PO1A 2.11 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 2EI Type1.5_Back 699 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8PO2A 2.28 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 26X Type1.5_Back 705 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8PO2B 2.28 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 26X Type1.5_Back 702 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9EWSA 2.435 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1H7N Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9EWTA 3.019 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1H7O Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9EWTB 3.019 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1H7O Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9GC4A 2.415 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa A1IZ7 Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9GC4B 2.415 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa A1IZ7 Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9HBOA 2.45 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-none TYR APEdihe_niiai APEdist_aaaa A1IUK Type1.5_Back 702 - 986 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9HBOB 2.45 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-in TYR APEdihe_iiiai APEdist_aaaa A1IUK Type1.5_Back 702 - 985 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9GC5A 1.909 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1IZ8 Type1.5_Back 699 - 1012 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9GC5B 1.909 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1IZ8 Type1.5_Back 699 - 1012 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2JIVA 3.5 Inactive DFGin‑None DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa HKI Type1.5_Back 700 - 984 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NK3A 1.586 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 92Q Type1.5_Back 601 - 888 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 8QQYA 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa WT3 Type1.5_Back 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 8BIOA 1.6 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa QRD Type1.5_Back 605 - 894 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5IA2A 1.619 Inactive DFGin‑BLBminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa L66 Type1.5_Back 598 - 888 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 4G2FA 1.699 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa C07 Type1.5_Back 609 - 903 0 None None Ephrin type-A receptor 3 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 4GK2A 2.195 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa L66 Type1.5_Back 609 - 903 0 None None Ephrin type-A receptor 3 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 4GK4A 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa L90 Type1.5_Back 609 - 903 0 None None Ephrin type-A receptor 3 Homo sapiens
TYR EPHB1 EPHB1_HUMAN 5MJAA 2.14 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 7O3 Type1.5_Back 609 - 892 0 PTR647,PTR778 None Ephrin type-B receptor 1 Homo sapiens
TYR EPHB1 EPHB1_HUMAN 5MJBA 2.23 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 7O3 Type1.5_Back 608 - 891 0 PTR647,PTR778 None Ephrin type-B receptor 1 Homo sapiens
TYR EPHB1 EPHB1_HUMAN 6UMWA 1.982 Inactive DFGin‑None DFGAsp-rot-in in-out none-none TYR APEdihe_nniai APEdist_aaaa CTC Type1.5_Back 611 - 889 0 PTR647 None Ephrin type-B receptor 1 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 2XVDA 1.7 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa AS6 Type1.5_Back 607 - 888 0 None Y774E Ephrin type-B receptor 4 Homo sapiens
TYR ERBB2 ERBB2_HUMAN 7PCDA 1.77 Inactive DFGin‑BLBminus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 70I Type1.5_Back 710 - 991 0 None None Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR ERBB2 ERBB2_HUMAN 7JXHA 3.27 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa VOY Type1.5_Back 706 - 992 0 None None Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR ERBB2 ERBB2_HUMAN 7JXHE 3.27 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nnnai APEdist_aaaa VOY Type1.5_Back 709 - 992 0 None None Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR ERBB2 ERBB2_HUMAN 7JXHB 3.27 Inactive DFGin‑None DFGAsp-rot-in out-out none-out TYR APEdihe_oiiai APEdist_aaaa VOY Type1.5_Back 707 - 996 0 None None Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR ERBB2 ERBB2_HUMAN 7JXHC 3.27 Inactive DFGin‑None DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa VOY Type1.5_Back 707 - 992 0 None None Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR ERBB2 ERBB2_HUMAN 7JXHD 3.27 Inactive DFGin‑None DFGAsp-rot-in out-out in-none TYR APEdihe_niiai APEdist_aaaa VOY Type1.5_Back 707 - 992 0 None None Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR ERBB2 ERBB2_HUMAN 7JXHF 3.27 Inactive DFGin‑None DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VOY Type1.5_Back 713 - 991 0 None None Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR ERBB2 ERBB2_HUMAN 7JXHG 3.27 Inactive DFGin‑None DFGAsp-rot-in out-out in-none TYR APEdihe_nniai APEdist_aaaa VOY Type1.5_Back 706 - 992 0 None None Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR ERBB2 ERBB2_HUMAN 7JXHH 3.27 Inactive DFGin‑None DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa VOY Type1.5_Back 707 - 992 0 None None Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR ERBB2 ERBB2_HUMAN 3PP0A 2.25 Inactive DFGin‑None DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa 03Q Type1.5_Back 706 - 993 0 None M706A,Q711L,M712L Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR ERBB2 ERBB2_HUMAN 3PP0B 2.25 Inactive DFGin‑None DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 03Q Type1.5_Back 706 - 1009 0 None M706A,Q711L,M712L Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR ERBB2 ERBB2_HUMAN 3RCDA 3.21 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 03P Type1.5_Back 713 - 1022 0 None None Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR ERBB2 ERBB2_HUMAN 3RCDC 3.21 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 03P Type1.5_Back 713 - 1022 0 None None Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR ERBB4 ERBB4_HUMAN 2R4BA 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-out TYR APEdihe_oiiai APEdist_aaaa GW7 Type1.5_Back 694 - 991 0 None None Receptor tyrosine-protein kinase erbB-4 Homo sapiens
TYR ERBB4 ERBB4_HUMAN 2R4BB 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-out TYR APEdihe_oiiai APEdist_aaaa GW7 Type1.5_Back 694 - 991 0 None None Receptor tyrosine-protein kinase erbB-4 Homo sapiens
TYR ERBB4 ERBB4_HUMAN 3BBTB 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa FMM Type1.5_Back 708 - 998 0 None None Receptor tyrosine-protein kinase erbB-4 Homo sapiens
TYR ERBB4 ERBB4_HUMAN 3BBTD 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa FMM Type1.5_Back 709 - 988 0 None None Receptor tyrosine-protein kinase erbB-4 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4RWKB 2.982 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 66T Type1.5_Back 459 - 763 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3C4FA 2.07 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_iioai APEdist_aaaa C4F Type1.5_Back 464 - 765 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3C4FB 2.07 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa C4F Type1.5_Back 464 - 765 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3RHXA 2.01 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 3RH Type1.5_Back 464 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3RHXB 2.01 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 3RH Type1.5_Back 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5A4CA 2.09 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa XOJ Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5A4CB 2.09 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa XOJ Type1.5_Back 461 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4NK9B 2.57 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 2K5 Type1.5_Back 460 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4V05A 2.57 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 66T Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4V05B 2.57 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 66T Type1.5_Back 459 - 764 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5EW8A 1.63 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5SF Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5EW8B 1.63 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5SF Type1.5_Back 461 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 2FGIA 2.5 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa PD1 Type1.5_Back 464 - 762 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 2FGIB 2.5 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa PD1 Type1.5_Back 461 - 761 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5B7VA 2.15 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa LWJ Type1.5_Back 464 - 763 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4WUNA 1.65 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa 66T Type1.5_Back 465 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4WUNB 1.65 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa 66T Type1.5_Back 461 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5UR1A 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY9 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C18A 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY5 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C19A 2.12 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa YY7 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C19B 2.12 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa YY7 Type1.5_Back 464 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C1BA 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY4 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C1BB 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa YY4 Type1.5_Back 463 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C1CA 2.15 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY6 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C1CB 2.15 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa YY6 Type1.5_Back 463 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C1OA 2.29 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa MK9 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C1OB 2.29 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa MK9 Type1.5_Back 464 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6MZQA 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa TZ0 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6MZQB 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa TZ0 Type1.5_Back 462 - 761 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4RWJA 2.489 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 66T Type1.5_Back 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4RWJB 2.489 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 66T Type1.5_Back 459 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3GQLA 2.8 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_oooai APEdist_aaaa GQL Type1.5_Back 463 - 774 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3TT0A 2.8 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 07J Type1.5_Back 461 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3TT0B 2.8 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnnao APEdist_aaaa 07J Type1.5_Back 459 - 763 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8Y22A 2.792 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1LW9 Type1.5_Back 459 - 762 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8Y22B 2.792 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1LW9 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6NVLA 2.7 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa XL6 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6NVLB 2.7 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL6 Type1.5_Back 461 - 761 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6NVLC 2.7 Inactive DFGin‑BLAplus DFGAsp-rot-none in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL6 Type1.5_Back 465 - 761 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6NVLD 2.7 Inactive DFGin‑BLAplus DFGAsp-rot-out in-none none-out TYR APEdihe_iioai APEdist_aaaa XL6 Type1.5_Back 471 - 762 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 7WCLA 2.495 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 8ZF Type1.5_Back 459 - 764 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 7WCLB 2.495 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 8ZF Type1.5_Back 458 - 763 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8XLOA 2.36 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1LVQ Type1.5_Back 462 - 764 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8XLOB 2.36 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa A1LVQ Type1.5_Back 458 - 763 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 8XZ7B 1.75 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1LWW Type1.5_Back 461 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6MZWA 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa TZ0 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5VNDA 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 9ES Type1.5_Back 463 - 765 0 None C488A,Y563C,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5VNDB 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 9ES Type1.5_Back 460 - 765 0 None C488A,Y563C,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6P68A 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa O1Y Type1.5_Back 462 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6P68B 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa O1Y Type1.5_Back 462 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6P68C 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa O1Y Type1.5_Back 463 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6P69A 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa O21 Type1.5_Back 462 - 765 0 None C488A,Y563C Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6P69B 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa O21 Type1.5_Back 461 - 762 0 None C488A,Y563C Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5ZV2A 2.86 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa LEV Type1.5_Back 463 - 762 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5ZV2B 2.86 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-out TYR APEdihe_nioai APEdist_aaaa LEV Type1.5_Back 461 - 764 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4NK9A 2.57 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 2K5 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5B7VB 2.15 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa LWJ Type1.5_Back 462 - 762 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 5UR1B 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY9 Type1.5_Back 464 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4RWLB 2.193 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 3ZC Type1.5_Back 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4F65B 2.26 Inactive DFGin‑None DFGAsp-rot-in in-in none-out TYR APEdihe_iioai APEdist_aaaa 0S9 Type1.5_Back 460 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6C18B 2.3 Inactive DFGin‑None DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY5 Type1.5_Back 466 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 6MZWB 2.2 Inactive DFGin‑None DFGAsp-rot-none in-in none-none TYR APEdihe_nnnai APEdist_aaaa TZ0 Type1.5_Back 463 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W3BA 2.23 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None D650V Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W3BB 2.23 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None D650V Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W3BC 2.23 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None D650V Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W3BD 2.23 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 465 - 764 0 None D650V Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W3DA 2.04 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None N549K,D650V Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W3DB 2.04 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 463 - 764 0 None N549K,D650V Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W3DC 2.04 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 766 0 None N549K,D650V Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W3DD 2.04 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 463 - 765 0 None N549K,D650V Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 6AGXA 2.95 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa 9WX Type1.5_Back 467 - 764 0 PTR586,PTR588,PTR656,PTR657 A628T Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 6AGXB 2.95 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa 9WX Type1.5_Back 467 - 764 0 PTR586,PTR588,PTR656,PTR657 A628T Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 6AGXC 2.95 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa 9WX Type1.5_Back 467 - 764 0 PTR586,PTR588,PTR656,PTR657 A628T Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 6AGXD 2.95 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa 9WX Type1.5_Back 467 - 764 0 PTR586,PTR588,PTR656,PTR657 A628T Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 3RI1A 2.1 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 3RH Type1.5_Back 468 - 765 0 None None Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W38A 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None N549D,D650V Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W38B 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None N549D,D650V Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W38C 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 465 - 764 0 None N549D,D650V Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W38D 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None N549D,D650V Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W2XA 2.98 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1AFR Type1.5_Back 458 - 765 0 None None Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8W2XB 2.98 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1AFR Type1.5_Back 458 - 765 0 None None Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8U1FA 3.33 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-none TYR APEdihe_niiai APEdist_aaaa UIM Type1.5_Back 460 - 764 0 None None Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8U1FB 3.33 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa UIM Type1.5_Back 472 - 765 0 None None Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 8STGB 3.79 Inactive DFGin‑None DFGAsp-rot-in in-out none-out TYR APEdihe_oiiai APEdist_aaaa WCJ Type1.5_Back 472 - 765 0 None None Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 9U3NB 3.25 Inactive DFGin‑None DFGAsp-rot-out in-in none-in TYR APEdihe_iiiai APEdist_aaaa A1ENT Type1.5_Back 470 - 764 0 None V564F Fibroblast growth factor receptor 2 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 6LVMA 2.53 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa EVR Type1.5_Back 472 - 755 0 PTR577,PTR647,PTR648 None Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 7DHLA 2.57 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa H6X Type1.5_Back 472 - 755 0 PTR577,PTR647,PTR648 None Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 8UDVA 2.348 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa WIQ Type1.5_Back 458 - 755 0 None V555M Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 8UDVB 2.348 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa WIQ Type1.5_Back 455 - 755 0 None V555M Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 8UDVC 2.348 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa WIQ Type1.5_Back 458 - 755 0 None V555M Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 8UDUA 1.737 Inactive DFGin‑BLBplus DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa WIQ Type1.5_Back 460 - 756 0 None P572S,P573G Fibroblast growth factor receptor 3 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4XCUA 1.71 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 40M Type1.5_Back 453 - 751 0 None L449M Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6NVGA 1.99 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL8 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6NVHA 1.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-none TYR APEdihe_nniai APEdist_aaaa XL6 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6NVIA 2.117 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-none TYR APEdihe_nniai APEdist_aaaa XL7 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6NVJA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL5 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6NVKA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL9 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6V9CA 1.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa QS7 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7DTZA 2.01 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa HHL Type1.5_Back 453 - 751 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6JPEA 1.601 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa BYU Type1.5_Back 452 - 751 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 5NWZB 2.37 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_niiai APEdist_aaaa 9CT Type1.5_Back 454 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7F3MA 2.289 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa GX3 Type1.5_Back 453 - 753 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7V29A 1.983 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5JR Type1.5_Back 454 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 7V29B 1.983 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5JR Type1.5_Back 454 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 8XLQA 1.95 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa A1LVQ Type1.5_Back 453 - 751 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4QQCA 2.4 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa 37O Type1.5_Back 445 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 5NWZA 2.37 Inactive DFGin‑BLBplus DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa 9CT Type1.5_Back 454 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4QQ5A 2.203 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa 37O Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4R6VA 2.353 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa FI3 Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGR FGR_HUMAN 7UY0A 2.55 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa VSE Type1.5_Back 80 - 527 0 PTR523 Q524E,P525E,G526I,D527P Tyrosine-protein kinase Fgr Homo sapiens
TYR FGR FGR_HUMAN 7UY0B 2.55 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa VSE Type1.5_Back 80 - 527 0 PTR523 Q524E,P525E,G526I,D527P Tyrosine-protein kinase Fgr Homo sapiens
TYR HCK HCK_HUMAN 2HK5A 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1BM Type1.5_Back 247 - 514 0 None None Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 5ZJ6B 1.696 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa VSE Type1.5_Back 249 - 518 0 None None Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 9BYJA 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa VSE Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VRYA 2.481 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa B43 Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VRYB 2.481 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa B43 Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS3A 2.17 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VSE Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS3B 2.17 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa VSE Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS4A 2.747 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VSF Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS4B 2.747 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VSF Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS6A 2.373 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VSH Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS6B 2.373 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VSH Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 4LUEA 3.04 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VSE Type1.5_Back 81 - 525 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 4LUEB 3.04 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VSE Type1.5_Back 81 - 525 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 5H09A 1.945 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa OOO Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 5H0BA 1.651 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa OOQ Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 5H0EA 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa OOS Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 5H0HA 1.72 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa OOV Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR HCK HCK_HUMAN 3VS1A 2.464 Inactive DFGin‑None DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VSA Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5TQ4A 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GY Type1.5_Back 841 - 1132 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5TQ5A 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GX Type1.5_Back 841 - 1131 0 None M1073S,F1076T Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5TQ8A 1.59 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GS Type1.5_Back 841 - 1131 0 None M1073S,F1076T Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 7Q7IA 1.78 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9I8 Type1.5_Back 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 7Q7KA 1.61 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9I5 Type1.5_Back 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 7Q7LA 1.97 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9I2 Type1.5_Back 843 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 7Q7WA 1.85 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9HR Type1.5_Back 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3JY9A 2.1 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa JZH Type1.5_Back 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3KCKA 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 3KC Type1.5_Back 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5TQ3A 2.69 Inactive DFGin‑None DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GZ Type1.5_Back 843 - 1132 0 PTR1007,PTR1008 M1073S,F1076T,I1126V Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5TQ3B 2.69 Inactive DFGin‑None DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GZ Type1.5_Back 843 - 1132 0 PTR1007,PTR1008 M1073S,F1076T,I1126V Tyrosine-protein kinase JAK2 Homo sapiens
TYR KDR VGFR2_HUMAN 2XIRA 1.5 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 00J Type1.5_Back 816 - 1168 0 None E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 4AGCA 2.0 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa AXI Type1.5_Back 801 - 1169 0 None E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KIT KIT_HUMAN 7KHKB 2.34 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa WEJ Type1.5_Back 567 - 929 0 None None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR LCK LCK_HUMAN 3BYMA 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa AM0 Type1.5_Back 230 - 501 0 PTR394 None Tyrosine-protein kinase Lck Homo sapiens
TYR LCK LCK_HUMAN 3KMMA 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa LHL Type1.5_Back 231 - 501 0 PTR394 Y505F Tyrosine-protein kinase Lck Homo sapiens
TYR LYN LYN_HUMAN 5XY1A 2.7 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 8H0 Type1.5_Back 239 - 502 0 None None Tyrosine-protein kinase Lyn Homo sapiens
TYR MERTK MERTK_HUMAN 6MEPA 2.893 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa 9VS Type1.5_Back 576 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 6MEPB 2.893 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 9VS Type1.5_Back 578 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR NTRK1 NTRK1_HUMAN 4PMSA 2.8 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 31X Type1.5_Back 501 - 787 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR RET RET_HUMAN 6NECA 1.87 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa XIN Type1.5_Back 713 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret Homo sapiens
TYR RET RET_HUMAN 6NECC 1.87 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa XIN Type1.5_Back 705 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret Homo sapiens
TYR RET RET_HUMAN 7DUAA 1.64 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa HJ0 Type1.5_Back 712 - 1011 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret Homo sapiens
TYR RET RET_HUMAN 7DUAB 1.64 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa HJ0 Type1.5_Back 705 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret Homo sapiens
TYR RET RET_HUMAN 7RUNA 3.51 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa 7QU Type1.5_Back 705 - 1012 0 PTR809,PTR905,SEP909,PTR928 None Proto-oncogene tyrosine-protein kinase receptor Ret Homo sapiens
TYR RET RET_HUMAN 7RUNB 3.51 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa 7QU Type1.5_Back 706 - 1012 0 PTR809,PTR905,SEP909,PTR928 None Proto-oncogene tyrosine-protein kinase receptor Ret Homo sapiens
TYR SRC SRC_HUMAN 6E6EB 2.15 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa HVY Type1.5_Back 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 6E6EE 2.15 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_ooiai APEdist_aaaa HVY Type1.5_Back 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 6E6EG 2.15 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa HVY Type1.5_Back 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 7NG7A 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa UCW Type1.5_Back 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR TNK2 ACK1_HUMAN 4ID7A 3.0 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa 1G0 Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 8HMTA 3.17 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 8HMTB 3.17 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa LWX Type1.5_Back 117 - 388 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 8HMTC 3.17 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 3EQRA 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa T74 Type1.5_Back 117 - 392 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 3EQRB 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa T74 Type1.5_Back 117 - 390 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 8HMTD 3.17 Inactive DFGin‑None DFGAsp-rot-out in-out in-in TYR APEdihe_iiiai APEdist_aaaa LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 3NYXA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa TZ1 Type1.5_Back 889 - 1176 0 None D1023N Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
CK1 CSNK1D KC1D_MOUSE 5X17A 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 3 - 292 0 None None Casein kinase I isoform delta Mus musculus
CK1 CSNK1D KC1D_MOUSE 5X17B 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 4 - 292 0 None None Casein kinase I isoform delta Mus musculus
CMGC MAPK14 MK14_MOUSE 4TYHB 3.0 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioo APEdist_iioo 39G Type1.5_Back 6 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8UA 1.48 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-out nonTYR APEdihe_aaoii APEdist_oooo SLS Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA7A 1.92 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SW7 Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA8A 1.78 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 2O6 Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 6MYNA 2.744 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi K6Y Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 6MYNB 2.744 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi K6Y Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 5T8OA 2.41 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 76Z Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 5T8OB 2.41 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 76Z Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 6G4YA 2.65 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ELZ Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 6G4YB 2.65 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ELZ Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 6G4ZA 2.84 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ELW Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 6G4ZB 2.84 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ELW Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 4G3EA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_nooi 0WC Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 4G3EB 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 0WC Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 7SZRA 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_ioii DYQ Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 7SZRB 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi DYQ Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWWA 1.93 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii A1D96 Type1.5_Back 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWWB 1.93 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_oooo A1D96 Type1.5_Back 13 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWZA 1.82 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii ZOV Type1.5_Back 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWZB 1.82 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo ZOV Type1.5_Back 14 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWXA 1.99 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn A1D96 Type1.5_Back 14 - 311 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWXB 1.99 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo A1D96 Type1.5_Back 14 - 313 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LFWA 1.59 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1D97 Type1.5_Back 5 - 312 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK4 RIPK4_MOUSE 5WNKA 3.11 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaooi APEdist_nnoo B6J Type1.5_Back 10 - 288 0 None D143N Receptor-interacting serine/threonine-protein kinase 4 Mus musculus
TYR ABL1 ABL1_MOUSE 3KF4A 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa B90 Type1.5_Back 229 - 514 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3KF4B 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa B90 Type1.5_Back 229 - 501 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1M52A 2.6 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa P17 Type1.5_Back 232 - 502 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1M52B 2.6 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa P17 Type1.5_Back 232 - 503 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1OPKA 1.8 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa P16 Type1.5_Back 64 - 512 0 None D363N Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL2 ABL2_MOUSE 4XLIA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa 1N1 Type1.5_Back 279 - 546 0 None None Tyrosine-protein kinase ABL2 Mus musculus
TYR ABL2 ABL2_MOUSE 4XLIB 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1N1 Type1.5_Back 279 - 546 0 None None Tyrosine-protein kinase ABL2 Mus musculus
TYR BTK BTK_MOUSE 9ZLMA 1.27 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa A1C2Z Type1.5_Back 390 - 659 0 None Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 6MNYA 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa JVP Type1.5_Back 395 - 656 0 None None Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 8FD9A 1.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa XQQ Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 8FF0A 2.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa 7GB Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJXA 2.86 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa A1BI1 Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9ME2A 3.38 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa A1BKW Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9ME3A 3.05 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa A1BJE Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR EPHA4 EPHA4_MOUSE 2XYUA 2.117 Inactive DFGin‑None DFGAsp-rot-in in-out none-none TYR APEdihe_nniai APEdist_aaaa Q9G Type1.5_Back 612 - 891 0 None None Ephrin type-A receptor 4 Mus musculus
TYR LYN LYN_MOUSE 2ZVAA 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 1N1 Type1.5_Back 239 - 502 0 None None Tyrosine-protein kinase Lyn Mus musculus
OTHER PKNB PKNB_MYCTU 5U94A 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi G93 Type1.5_Back 3 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
AGC PKG KGP_PLAVS 5EZRA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4ZS Type1.5_Back 2 - 815 0 None None cGMP-dependent protein kinase Plasmodium vivax
CMGC MAPK1 MK01_RAT 4N4SA 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaioi APEdist_iioo 2H1 Type1.5_Back 8 - 356 0 None Q103A,C164L Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 4N4SB 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaioi APEdist_nnno 2H1 Type1.5_Back 8 - 356 0 None Q103A,C164L Mitogen-activated protein kinase 1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 6OL2A 2.1 Inactive DFGin‑BLBminus DFGAsp-rot-out na-na out-out nonTYR APEdihe_aaiio APEdist_oooo MU7 Type1.5_Back 203 - 481 0 None S382A Serine/threonine-protein kinase WNK1 Rattus norvegicus
CK1 CKI1 CKI1_SCHPO 1EH4A 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iioi IC1 Type1.5_Back 6 - 298 0 None None Casein kinase I homolog 1 Schizosaccharomyces pombe
CK1 CKI1 CKI1_SCHPO 1EH4B 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iioi IC1 Type1.5_Back 6 - 298 0 None None Casein kinase I homolog 1 Schizosaccharomyces pombe
CAMK CDPK1 Q9BJF5_TOXGO 3V51A 1.95 Inactive None‑None DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaooi APEdist_iooo I76 Type1.5_Back 43 - 507 0 None None non-specific serine/threonine protein kinase Toxoplasma gondii
CAMK AURKBA AUKBA_XENLA 5EYKA 1.93 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5U5 Type1.5_Back 88 - 355 0 TPO248 G96V Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2VRXB 1.86 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 447 Type1.5_Back 77 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis

All / All / Type1.5_Back

Total number of chains: 79
Active chains: 14
Total number of genes: 19
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 54 68.4% 3E8EA
DFGin BLBplus 9 11.4% 9ZLMA
DFGin BLBminus 6 7.6% 5RA7A
DFGin None 3 3.8% 4C35A
DFGout None 3 3.8% 1OPKA
DFGin ABAminus 2 2.5% 2VRXB
None None 2 2.5% 3V51A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AGC PRKACA KAPCA_BOVIN 3E8CA 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 8 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8CB 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 5 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8CC 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 8 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8CD 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 5 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8CE 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 14 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8CF 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G96 Type1.5_Back 8 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8EA 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 8 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8EB 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 13 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8EE 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 8 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8EI 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 4 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8EL 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 14 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 3E8EP 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G98 Type1.5_Back 8 - 351 0 SEP11,TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC PRKACA KAPCA_BOVIN 4C35A 2.19 Inactive DFGin‑None DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NU3 Type1.5_Back 11 - 351 0 SEP11,SEP140,TPO198,SEP339 F55Y,M121L,V124L,L174M,Q182K cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
TYR SRC SRC_CHICK 3QLGA 2.75 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa 1N1 Type1.5_Back 258 - 533 0 None L317I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3QLGB 2.75 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa 1N1 Type1.5_Back 256 - 533 0 None L317I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3EN4B 2.55 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa KS1 Type1.5_Back 257 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3UQFA 2.27 Inactive DFGin‑BLAminus DFGAsp-rot-out in-none none-none TYR APEdihe_nnnai APEdist_aaaa BK5 Type1.5_Back 258 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4DGGB 2.65 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa I76 Type1.5_Back 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 6WIWB 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nnnai APEdist_aaaa I14 Type1.5_Back 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 7D57B 2.104 Inactive DFGin‑BLAminus DFGAsp-rot-none in-out in-none TYR APEdihe_nniai APEdist_aaaa 37O Type1.5_Back 257 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3G5DA 2.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 1N1 Type1.5_Back 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3G5DB 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa 1N1 Type1.5_Back 258 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3SVVA 2.204 Inactive DFGin‑BLBminus DFGAsp-rot-out in-in out-none TYR APEdihe_nnnai APEdist_aaaa VSP Type1.5_Back 257 - 533 0 None T338C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3SVVB 2.204 Inactive DFGin‑BLBminus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa VSP Type1.5_Back 256 - 533 0 None T338C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4YBKA 2.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 4B7 Type1.5_Back 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5TEHA 2.99 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa S56 Type1.5_Back 256 - 533 0 None V281C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 6WIWA 2.3 Inactive None‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nnnai APEdist_aaaa I14 Type1.5_Back 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
CK1 CSNK1D KC1D_MOUSE 5X17A 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 3 - 292 0 None None Casein kinase I isoform delta Mus musculus
CK1 CSNK1D KC1D_MOUSE 5X17B 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP Type1.5_Back 4 - 292 0 None None Casein kinase I isoform delta Mus musculus
CMGC MAPK14 MK14_MOUSE 4TYHB 3.0 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out none-out nonTYR APEdihe_aaioo APEdist_iioo 39G Type1.5_Back 6 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8UA 1.48 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-out nonTYR APEdihe_aaoii APEdist_oooo SLS Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA7A 1.92 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SW7 Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA8A 1.78 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 2O6 Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 6MYNA 2.744 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi K6Y Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 6MYNB 2.744 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi K6Y Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 5T8OA 2.41 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 76Z Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 5T8OB 2.41 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 76Z Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 6G4YA 2.65 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ELZ Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 6G4YB 2.65 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ELZ Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 6G4ZA 2.84 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ELW Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 6G4ZB 2.84 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi ELW Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 4G3EA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_nooi 0WC Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 4G3EB 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 0WC Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 7SZRA 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_ioii DYQ Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
STE MAP3K14 M3K14_MOUSE 7SZRB 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iooi DYQ Type1.5_Back 334 - 675 0 None None Mitogen-activated protein kinase kinase kinase 14 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWWA 1.93 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii A1D96 Type1.5_Back 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWWB 1.93 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_oooo A1D96 Type1.5_Back 13 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWZA 1.82 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aaiii APEdist_nnii ZOV Type1.5_Back 13 - 312 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWZB 1.82 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo ZOV Type1.5_Back 14 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWXA 1.99 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none nonTYR APEdihe_aanii APEdist_nnnn A1D96 Type1.5_Back 14 - 311 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IWXB 1.99 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo A1D96 Type1.5_Back 14 - 313 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9LFWA 1.59 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1D97 Type1.5_Back 5 - 312 0 None R69H Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK4 RIPK4_MOUSE 5WNKA 3.11 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaooi APEdist_nnoo B6J Type1.5_Back 10 - 288 0 None D143N Receptor-interacting serine/threonine-protein kinase 4 Mus musculus
TYR ABL1 ABL1_MOUSE 3KF4A 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa B90 Type1.5_Back 229 - 514 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3KF4B 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa B90 Type1.5_Back 229 - 501 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1M52A 2.6 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa P17 Type1.5_Back 232 - 502 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1M52B 2.6 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa P17 Type1.5_Back 232 - 503 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1OPKA 1.8 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa P16 Type1.5_Back 64 - 512 0 None D363N Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL2 ABL2_MOUSE 4XLIA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa 1N1 Type1.5_Back 279 - 546 0 None None Tyrosine-protein kinase ABL2 Mus musculus
TYR ABL2 ABL2_MOUSE 4XLIB 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1N1 Type1.5_Back 279 - 546 0 None None Tyrosine-protein kinase ABL2 Mus musculus
TYR BTK BTK_MOUSE 9ZLMA 1.27 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa A1C2Z Type1.5_Back 390 - 659 0 None Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 6MNYA 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa JVP Type1.5_Back 395 - 656 0 None None Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 8FD9A 1.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa XQQ Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 8FF0A 2.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa 7GB Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9EJXA 2.86 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa A1BI1 Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9ME2A 3.38 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa A1BKW Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR BTK BTK_MOUSE 9ME3A 3.05 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa A1BJE Type1.5_Back 396 - 659 0 None K430R,L542M,S543T,V555T,R562K,S564A,P565S,Y617P Tyrosine-protein kinase BTK Mus musculus
TYR EPHA4 EPHA4_MOUSE 2XYUA 2.117 Inactive DFGin‑None DFGAsp-rot-in in-out none-none TYR APEdihe_nniai APEdist_aaaa Q9G Type1.5_Back 612 - 891 0 None None Ephrin type-A receptor 4 Mus musculus
TYR LYN LYN_MOUSE 2ZVAA 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 1N1 Type1.5_Back 239 - 502 0 None None Tyrosine-protein kinase Lyn Mus musculus
OTHER PKNB PKNB_MYCTU 5U94A 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_nnoi G93 Type1.5_Back 3 - 278 0 None None Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
AGC PKG KGP_PLAVS 5EZRA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 4ZS Type1.5_Back 2 - 815 0 None None cGMP-dependent protein kinase Plasmodium vivax
CMGC MAPK1 MK01_RAT 4N4SA 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaioi APEdist_iioo 2H1 Type1.5_Back 8 - 356 0 None Q103A,C164L Mitogen-activated protein kinase 1 Rattus norvegicus
CMGC MAPK1 MK01_RAT 4N4SB 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out nonTYR APEdihe_aaioi APEdist_nnno 2H1 Type1.5_Back 8 - 356 0 None Q103A,C164L Mitogen-activated protein kinase 1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 6OL2A 2.1 Inactive DFGin‑BLBminus DFGAsp-rot-out na-na out-out nonTYR APEdihe_aaiio APEdist_oooo MU7 Type1.5_Back 203 - 481 0 None S382A Serine/threonine-protein kinase WNK1 Rattus norvegicus
CK1 CKI1 CKI1_SCHPO 1EH4A 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iioi IC1 Type1.5_Back 6 - 298 0 None None Casein kinase I homolog 1 Schizosaccharomyces pombe
CK1 CKI1 CKI1_SCHPO 1EH4B 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaiii APEdist_iioi IC1 Type1.5_Back 6 - 298 0 None None Casein kinase I homolog 1 Schizosaccharomyces pombe
CAMK CDPK1 Q9BJF5_TOXGO 3V51A 1.95 Inactive None‑None DFGAsp-rot-out out-out out-out nonTYR APEdihe_aaooi APEdist_iooo I76 Type1.5_Back 43 - 507 0 None None non-specific serine/threonine protein kinase Toxoplasma gondii
CAMK AURKBA AUKBA_XENLA 5EYKA 1.93 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5U5 Type1.5_Back 88 - 355 0 TPO248 G96V Aurora kinase B-A Xenopus laevis
CAMK AURKBA AUKBA_XENLA 2VRXB 1.86 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 447 Type1.5_Back 77 - 355 0 TPO248 None Aurora kinase B-A Xenopus laevis