AURKC (Aurora kinase C)

Group: CAMK

Uniprot: AURKC_HUMAN

Domain boundary: 43 - 293

Total number of chains: 5

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	AF-Q9UQB9-K1A
DFGin	ABAminus	4	6GR8A

Database table as tsv

PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
9ESAAAA	2.8	Inactive	DFGin	ABAminus	out-out	out-out	No_ligand	No_ligand	32 - 306	R195A,R196A,K197A	None	0
9ESABBB	2.8	Inactive	DFGin	ABAminus	out-out	out-out	No_ligand	No_ligand	32 - 306	R195A,R196A,K197A	None	0
6GR9A	2.25	Inactive	DFGin	ABAminus	out-out	in-in	VX6	Type1	37 - 305	None	X39,X198	0
6GR8A	1.75	Inactive	DFGin	ABAminus	out-out	in-in	F8Z	Type1.5_Front	36 - 303	None	X39,X198	0
AF-Q9UQB9-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	35 - 301	None	None	0

AURKC (Aurora kinase C)

Group: CAMK

Total number of chains: 5

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	AF-Q9UQB9-K1A
DFGin	ABAminus	4	6GR8A

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Homo sapiens	AURKC_HUMAN	9ESAAAA	2.8	Inactive	DFGin	ABAminus	out-out	out-out	No_ligand	No_ligand	32 - 306	R195A,R196A,K197A	None	0
Homo sapiens	AURKC_HUMAN	9ESABBB	2.8	Inactive	DFGin	ABAminus	out-out	out-out	No_ligand	No_ligand	32 - 306	R195A,R196A,K197A	None	0
Homo sapiens	AURKC_HUMAN	6GR9A	2.25	Inactive	DFGin	ABAminus	out-out	in-in	VX6	Type1	37 - 305	None	X39,X198	0
Homo sapiens	AURKC_HUMAN	6GR8A	1.75	Inactive	DFGin	ABAminus	out-out	in-in	F8Z	Type1.5_Front	36 - 303	None	X39,X198	0
Homo sapiens	AURKC_HUMAN	AF-Q9UQB9-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	35 - 301	None	None	0

AURKC (Aurora kinase C)

No non-human structures known.