CK1_VRK2 (Serine/threonine-protein kinase VRK2)

Total number of chains: 9
Active chains: 6
Uniprot: VRK2_HUMAN
Kinase Domain Residues: 29 - 315
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 88.9% AF-Q86Y07-K1A
DFGin ABAminus 1 11.1% 5UU1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q86Y07-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 21 - 323 0 None None Serine/threonine-protein kinase VRK2
AF-Q86Y07-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 21 - 323 0 None None Serine/threonine-protein kinase VRK2
2V62A 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 330 0 None None Serine/threonine-protein kinase VRK2
2V62B 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 330 0 None None Serine/threonine-protein kinase VRK2
8Q1ZA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IKD Type1 15 - 330 0 None None Serine/threonine-protein kinase VRK2
9FETA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii REB Type1.5_Back 15 - 330 0 None None Serine/threonine-protein kinase VRK2
5UU1A 2.0 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 7DZ Type1.5_Back 14 - 328 0 None None Serine/threonine-protein kinase VRK2
6NCGA 2.45 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi KJD Type1.5_Back 14 - 326 0 None None Serine/threonine-protein kinase VRK2
6NCGB 2.45 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_nnii KJD Type1.5_Back 16 - 326 0 None None Serine/threonine-protein kinase VRK2

CK1_VRK2 (Serine/threonine-protein kinase VRK2)

Total number of chains: 9
Active chains: 6
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 88.9% AF-Q86Y07-K1A
DFGin ABAminus 1 11.1% 5UU1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
VRK2_HUMAN AF-Q86Y07-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 21 - 323 0 None None Serine/threonine-protein kinase VRK2 Homo sapiens
VRK2_HUMAN AF-Q86Y07-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 21 - 323 0 None None Serine/threonine-protein kinase VRK2 Homo sapiens
VRK2_HUMAN 2V62A 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 330 0 None None Serine/threonine-protein kinase VRK2 Homo sapiens
VRK2_HUMAN 2V62B 1.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 15 - 330 0 None None Serine/threonine-protein kinase VRK2 Homo sapiens
VRK2_HUMAN 8Q1ZA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IKD Type1 15 - 330 0 None None Serine/threonine-protein kinase VRK2 Homo sapiens
VRK2_HUMAN 9FETA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii REB Type1.5_Back 15 - 330 0 None None Serine/threonine-protein kinase VRK2 Homo sapiens
VRK2_HUMAN 5UU1A 2.0 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 7DZ Type1.5_Back 14 - 328 0 None None Serine/threonine-protein kinase VRK2 Homo sapiens
VRK2_HUMAN 6NCGA 2.45 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiii APEdist_iooi KJD Type1.5_Back 14 - 326 0 None None Serine/threonine-protein kinase VRK2 Homo sapiens
VRK2_HUMAN 6NCGB 2.45 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaiii APEdist_nnii KJD Type1.5_Back 16 - 326 0 None None Serine/threonine-protein kinase VRK2 Homo sapiens

CK1_VRK2 (Serine/threonine-protein kinase VRK2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism