AGC_RPS6KB1 (Ribosomal protein S6 kinase beta-1)

Total number of chains: 26
Active chains: 2
Uniprot: KS6B1_HUMAN
Kinase Domain Residues: 91 - 352
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 14 53.8% 4L3JA
DFGin BLAminus 6 23.1% AF-P23443-K1A
DFGin None 4 15.4% 3WF7A
None None 2 7.7% 3A60B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P23443-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 83 - 360 0 None None Ribosomal protein S6 kinase beta-1
AF-P23443-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 83 - 360 0 None None Ribosomal protein S6 kinase beta-1
4RLPA 2.79 Inactive DFGin‑ABAminus none-none in-out nonTYR APEdihe_aaiii APEdist_nnno 72B Type1 85 - 372 0 None None Ribosomal protein S6 kinase beta-1
4L3JA 2.1 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 85 - 375 0 None None Ribosomal protein S6 kinase beta-1
4L3LA 2.1 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 85 - 375 0 None None Ribosomal protein S6 kinase beta-1
7N91A 3.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 1RJ Type1 85 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1
7N91B 3.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 1RJ Type1 85 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1
7N93A 2.74 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnoo 1SK Type1 87 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1
7N93B 2.74 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 1SK Type1 85 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1
3A62A 2.35 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_iioo STU Type1 85 - 372 0 TPO252 None Ribosomal protein S6 kinase beta-1
3WE4A 1.995 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 85 - 374 0 TPO252 None Ribosomal protein S6 kinase beta-1
3WF5A 2.099 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo FZ8 Type1 85 - 374 0 TPO252 None Ribosomal protein S6 kinase beta-1
3WF6A 2.031 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo FZ9 Type1 85 - 374 0 TPO252 None Ribosomal protein S6 kinase beta-1
4L45A 2.9 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 5FI Type1 81 - 417 0 None T412E Ribosomal protein S6 kinase beta-1
4L42A 2.8 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo 5FI Type1 84 - 417 0 None S403E,A404E,N405Q,Q406E,V407M,L409R,G410D,T412E,V414I,P416D,S417W Ribosomal protein S6 kinase beta-1
4L46A 3.01 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 80 - 417 0 TPO412 None Ribosomal protein S6 kinase beta-1
3WF8A 1.975 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo F76 Type1 85 - 372 0 TPO252 None Ribosomal protein S6 kinase beta-1
3WF9A 2.035 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo FS7 Type1 85 - 372 0 TPO252 None Ribosomal protein S6 kinase beta-1
4L43A 3.0 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 5FI Type1 81 - 417 0 None T412A Ribosomal protein S6 kinase beta-1
4L44A 2.9 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 81 - 417 0 None T412A Ribosomal protein S6 kinase beta-1
4RLOA 2.527 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 3T3 Type1 85 - 371 0 None None Ribosomal protein S6 kinase beta-1
3A60A 2.8 Inactive DFGin‑None in-out out-none nonTYR APEdihe_aanii APEdist_nnnn STU Type1 85 - 371 0 None None Ribosomal protein S6 kinase beta-1
3A61A 3.43 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaioi APEdist_nnno STU Type1 87 - 371 0 None None Ribosomal protein S6 kinase beta-1
3WF7A 1.85 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iooo FS9 Type1 83 - 374 0 TPO252 None Ribosomal protein S6 kinase beta-1
4RLOB 2.527 Inactive None‑None none-none out-out nonTYR APEdihe_aanoi APEdist_nnnn STU Type1 85 - 372 0 None None Ribosomal protein S6 kinase beta-1
3A60B 2.8 Inactive None‑None none-none in-out nonTYR APEdihe_aaioi APEdist_nnoo STU Type1 85 - 372 0 None None Ribosomal protein S6 kinase beta-1

AGC_RPS6KB1 (Ribosomal protein S6 kinase beta-1)

Total number of chains: 26
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 14 53.8% 4L3JA
DFGin BLAminus 6 23.1% AF-P23443-K1A
DFGin None 4 15.4% 3WF7A
None None 2 7.7% 3A60B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
KS6B1_HUMAN AF-P23443-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 83 - 360 0 None None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN AF-P23443-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 83 - 360 0 None None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 4RLPA 2.79 Inactive DFGin‑ABAminus none-none in-out nonTYR APEdihe_aaiii APEdist_nnno 72B Type1 85 - 372 0 None None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 4L3JA 2.1 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 85 - 375 0 None None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 4L3LA 2.1 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 85 - 375 0 None None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 7N91A 3.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 1RJ Type1 85 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 7N91B 3.0 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 1RJ Type1 85 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 7N93A 2.74 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnoo 1SK Type1 87 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 7N93B 2.74 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 1SK Type1 85 - 418 0 TPO390,SEP394 T412E Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 3A62A 2.35 Inactive DFGin‑ABAminus in-in none-out nonTYR APEdihe_aaioi APEdist_iioo STU Type1 85 - 372 0 TPO252 None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 3WE4A 1.995 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 85 - 374 0 TPO252 None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 3WF5A 2.099 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo FZ8 Type1 85 - 374 0 TPO252 None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 3WF6A 2.031 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo FZ9 Type1 85 - 374 0 TPO252 None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 4L45A 2.9 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 5FI Type1 81 - 417 0 None T412E Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 4L42A 2.8 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo 5FI Type1 84 - 417 0 None S403E,A404E,N405Q,Q406E,V407M,L409R,G410D,T412E,V414I,P416D,S417W Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 4L46A 3.01 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 80 - 417 0 TPO412 None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 3WF8A 1.975 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo F76 Type1 85 - 372 0 TPO252 None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 3WF9A 2.035 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo FS7 Type1 85 - 372 0 TPO252 None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 4L43A 3.0 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 5FI Type1 81 - 417 0 None T412A Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 4L44A 2.9 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iooo 5FI Type1 81 - 417 0 None T412A Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 4RLOA 2.527 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioi APEdist_nnno 3T3 Type1 85 - 371 0 None None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 3A60A 2.8 Inactive DFGin‑None in-out out-none nonTYR APEdihe_aanii APEdist_nnnn STU Type1 85 - 371 0 None None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 3A61A 3.43 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaioi APEdist_nnno STU Type1 87 - 371 0 None None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 3WF7A 1.85 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iooo FS9 Type1 83 - 374 0 TPO252 None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 4RLOB 2.527 Inactive None‑None none-none out-out nonTYR APEdihe_aanoi APEdist_nnnn STU Type1 85 - 372 0 None None Ribosomal protein S6 kinase beta-1 Homo sapiens
KS6B1_HUMAN 3A60B 2.8 Inactive None‑None none-none in-out nonTYR APEdihe_aaioi APEdist_nnoo STU Type1 85 - 372 0 None None Ribosomal protein S6 kinase beta-1 Homo sapiens

AGC_RPS6KB1 (Ribosomal protein S6 kinase beta-1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism