Ligand: 5E1

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 5DR6A
DFGin BLAminus 1 50.0% 5DR2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK AURKA AURKA_HUMAN 5DR6A 2.534 Inactive DFGin‑ABAminus out-in in-out nonTYR APEdihe_aaiii APEdist_nnoo 5E1, SKE Allosteric, Type1 127 - 390 0 None T287A Aurora kinase A
CAMK AURKA AURKA_HUMAN 5DR2A 2.46 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 5E1, ATP Allosteric, ATPlike 128 - 390 0 None T287A Aurora kinase A

Ligand: 5E1

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 5DR6A
DFGin BLAminus 1 50.0% 5DR2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK AURKA AURKA_HUMAN 5DR6A 2.534 Inactive DFGin‑ABAminus out-in in-out nonTYR APEdihe_aaiii APEdist_nnoo 5E1, SKE Allosteric, Type1 127 - 390 0 None T287A Aurora kinase A Homo sapiens
CAMK AURKA AURKA_HUMAN 5DR2A 2.46 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 5E1, ATP Allosteric, ATPlike 128 - 390 0 None T287A Aurora kinase A Homo sapiens

Ligand: 5E1

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism