5U7Q

ROCK2 (Rho-associated protein kinase 2)
Group: AGC
Uniprot: ROCK2_HUMAN
Organism: Homo sapiens
Domain boundary: 92 - 354
Resolu: 3.15

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in No_ligand No_ligand 25 - 417 0
B Inactive DFGin ABAminus in-in in-out No_ligand No_ligand 28 - 417 0
C Inactive DFGin ABAminus in-in in-in No_ligand No_ligand 23 - 417 0
D Inactive DFGin ABAminus in-in in-out No_ligand No_ligand 27 - 417 3
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
        32         42         52         62 
gasrQRKLEA LIRDPRSPIN VESLLDGLNS LVLDLDFPAL 
        72         82         92        102 
RKNKNIDNFL NRYEKIVKKI RGLQMKAEDY DVVKVIGRGA 
       112        122        132        142 
FGEVQLVRHK ASQKVYAMKL LSKFEMIKRS DSAFFWEERD 
       152        162        172        182 
IMAFANSPWV VQLFYAFQDD RYLYMVMEYM PGGDLVNLMS 
       192        202        212        222 
NYDVPEKWAK FYTAEVVLAL DAIHSMGLIH RDVKPDNMLL 
       232        242        252        262 
DKHGHLKLAD FGTCMKMDET GMVhcdTAVG TPDYISPEVL 
       272        282        292        302 
KSQGGDGFYG RECDWWSVGV FLYEMLVGDT PFYADSLVGT 
       312        322        332        342 
YSKIMDHKNS LCFPEDAEIS KHAKNLICAF LTDREVRLGR 
       352        362        372        382 
NGVEEIRQHP FFKNDQWHWD NIRETAAPVV PELSSDIDSS 
       392        402        412 
NFDDIEddkg dVETFPIPKA FVGNQLPFIG FTYYR
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None