Ligand: 0MX

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein

Ligand: 0MX

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 100.0% 4E1ZA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR TYK2-2 TYK2_MOUSE 4E1ZA 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0MX Type1 884 - 1174 0 None D1020A Non-receptor tyrosine-protein kinase TYK2 Mus musculus

Ligand: 0MX

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 100.0% 4E1ZA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR TYK2-2 TYK2_MOUSE 4E1ZA 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 0MX Type1 884 - 1174 0 None D1020A Non-receptor tyrosine-protein kinase TYK2 Mus musculus