4WOT

ROCK2 (Rho-associated protein kinase 2)
Group: AGC
Uniprot: ROCK2_HUMAN
Organism: Homo sapiens
Domain boundary: 92 - 354
Resolu: 2.93

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-out 3SG Type1 22 - 417 3
B Inactive DFGin ABAminus in-in in-in 3SG Type1 22 - 417 0
C Inactive DFGin ABAminus in-in in-in 3SG Type1 22 - 417 0
D Inactive DFGin ABAminus in-in in-out 3SG Type1 23 - 417 2
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
        31         41         51         61 
aGASRQRKLE ALIRDPRSPI NVESLLDGLN SLVLDLDFPA 
        71         81         91        101 
LRKNKNIDNF LNRYEKIVKK IRGLQMKAED YDVVKVIGRG 
       111        121        131        141 
AFGEVQLVRH KASQKVYAMK LLSKFEMIKR SDSAFFWEER 
       151        161        171        181 
DIMAFANSPW VVQLFYAFQD DRYLYMVMEY MPGGDLVNLM 
       191        201        211        221 
SNYDVPEKWA KFYTAEVVLA LDAIHSMGLI HRDVKPDNML 
       231        241        251        261 
LDKHGHLKLA DFGTCMKMDE TGMVHCdtAV GTPDYISPEV 
       271        281        291        301 
LKSQGGDGFY GRECDWWSVG VFLYEMLVGD TPFYADSLVG 
       311        321        331        341 
TYSKIMDHKN SLCFPEDAEI SKHAKNLICA FLTDREVRLG 
       351        361        371        381 
RNGVEEIRQH PFFKNDQWHW DNIRETAAPV VPELSSDIDS 
       391        401        411 
SNFDDIEDdk gdVETFPIPK AFVGNQLPFI GFTYYR
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None