4EHZ

JAK1 (Tyrosine-protein kinase JAK1)
Group: TYR
Uniprot: JAK1_HUMAN
Organism: Homo sapiens
Domain boundary: 875 - 1153
Resolu: 2.174

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in JAK Type1 858 - 1154 0
B Inactive DFGin ABAminus in-in in-in JAK Type1 865 - 1154 0
C Inactive DFGin ABAminus in-in in-in JAK Type1 866 - 1154 0
D Inactive DFGin ABAminus in-in in-in JAK Type1 865 - 1154 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
       862        872        882        892 
gdivsekkpa teVDPTHFEK RFLKRIRDLG EGHFGKVELC 
       902        912        922        932 
RYDPEGDNTG EQVAVKSLKP esggNHIADL KKEIEILRNL 
       942        952        962        972 
YHENIVKYKG ICTedggNGI KLIMEFLPSG SLKEYLPKNK 
       982        992       1002       1012 
NKINLKQQLK YAVQICKGMD YLGSRQYVHR DLAARNVLVE 
      1022       1032       1042       1052 
SEHQVKIGDF GLTKAIETDK EYYTVKDDRD SPVFWYAPEC 
      1062       1072       1082       1092 
LMQSKFYIAS DVWSFGVTLH ELLTYCDSDS SPMALFLKMI 
      1102       1112       1122       1132 
GPTHGQMTVT RLVNTLKEGK RLPCPPNCPD EVYQLMRKCW 
      1142       1152 
EFQPSNRTSF QNLIEGFEAL LK
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X1034,X1035