Ligand: 33A

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 2OK1A
DFGin BLAminus 1 50.0% 2OJIA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK1 MK01_HUMAN 2OJIA 2.6 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii 33A Type1 15 - 358 0 None None Mitogen-activated protein kinase 1
CMGC MAPK10 MK10_HUMAN 2OK1A 2.4 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 33A Type1 46 - 400 0 None None Mitogen-activated protein kinase 10

Ligand: 33A

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 2OK1A
DFGin BLAminus 1 50.0% 2OJIA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK1 MK01_HUMAN 2OJIA 2.6 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaiii APEdist_oiii 33A Type1 15 - 358 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK10 MK10_HUMAN 2OK1A 2.4 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 33A Type1 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens

Ligand: 33A

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism