Ligand: 824

Total number of chains: 7
Active chains: 0
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 71.4% 2X7FB
DFGin ABAminus 1 14.3% 4C58A
DFGin None 1 14.3% 2X7FE
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
OTHER GAK GAK_HUMAN 4C58A 2.16 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 824 Type1.5_Back 27 - 333 0 None None Cyclin-G-associated kinase
OTHER WEE1 WEE1_HUMAN 1X8BA 1.81 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 824 Type1 291 - 569 0 None None Wee1-like protein kinase
STE TNIK TNIK_HUMAN 2X7FA 2.8 Inactive DFGin‑BLAminus in-none out-out nonTYR APEdihe_aaini APEdist_nnno 824 Type1 15 - 313 0 None None TRAF2 and NCK-interacting protein kinase
STE TNIK TNIK_HUMAN 2X7FB 2.8 Inactive DFGin‑BLAminus in-none out-out nonTYR APEdihe_aaioi APEdist_nnno 824 Type1 13 - 313 0 None None TRAF2 and NCK-interacting protein kinase
STE TNIK TNIK_HUMAN 2X7FC 2.8 Inactive DFGin‑BLAminus in-none out-none nonTYR APEdihe_aanni APEdist_nnnn 824 Type1 14 - 313 0 None None TRAF2 and NCK-interacting protein kinase
STE TNIK TNIK_HUMAN 2X7FD 2.8 None DFGin‑BLAminus in-none none-none nonTYR APEdihe_aanni APEdist_nnnn 824 Type1 17 - 306 0 None None TRAF2 and NCK-interacting protein kinase
STE TNIK TNIK_HUMAN 2X7FE 2.8 Inactive DFGin‑None in-none none-none nonTYR APEdihe_aanni APEdist_nnnn 824 Type1 14 - 309 0 None None TRAF2 and NCK-interacting protein kinase

Ligand: 824

Total number of chains: 7
Active chains: 0
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 71.4% 2X7FB
DFGin ABAminus 1 14.3% 4C58A
DFGin None 1 14.3% 2X7FE
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER GAK GAK_HUMAN 4C58A 2.16 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 824 Type1.5_Back 27 - 333 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 1X8BA 1.81 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi 824 Type1 291 - 569 0 None None Wee1-like protein kinase Homo sapiens
STE TNIK TNIK_HUMAN 2X7FA 2.8 Inactive DFGin‑BLAminus in-none out-out nonTYR APEdihe_aaini APEdist_nnno 824 Type1 15 - 313 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
STE TNIK TNIK_HUMAN 2X7FB 2.8 Inactive DFGin‑BLAminus in-none out-out nonTYR APEdihe_aaioi APEdist_nnno 824 Type1 13 - 313 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
STE TNIK TNIK_HUMAN 2X7FC 2.8 Inactive DFGin‑BLAminus in-none out-none nonTYR APEdihe_aanni APEdist_nnnn 824 Type1 14 - 313 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
STE TNIK TNIK_HUMAN 2X7FD 2.8 None DFGin‑BLAminus in-none none-none nonTYR APEdihe_aanni APEdist_nnnn 824 Type1 17 - 306 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens
STE TNIK TNIK_HUMAN 2X7FE 2.8 Inactive DFGin‑None in-none none-none nonTYR APEdihe_aanni APEdist_nnnn 824 Type1 14 - 309 0 None None TRAF2 and NCK-interacting protein kinase Homo sapiens

Ligand: 824

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism