Ligand: DQX

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 3KRRA
DFGin None 1 50.0% 5UT4A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR JAK2-2 JAK2_HUMAN 3KRRA 1.8 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai DQX Type1 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5UT4A 2.0 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao DQX Type1 537 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2

Ligand: DQX

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 3KRRA
DFGin None 1 50.0% 5UT4A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR JAK2-2 JAK2_HUMAN 3KRRA 1.8 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai DQX Type1 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5UT4A 2.0 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao DQX Type1 537 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens

Ligand: DQX

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism