STE_STK10 (Serine/threonine-protein kinase 10)

Total number of chains: 27
Uniprot: STK10_HUMAN
Kinase Domain Residues: 36 - 294
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 9 AF-O94804-K1A
DFGin ABAminus 2 4USEA
DFGin BLBminus 1 7QGPA
DFGin None 2 5AJQA
DFGout BBAminus 3 6EIMB
DFGout None 8 4EQUB
None None 2 5OWQB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
4USEA 2.65 Inactive DFGin‑ABAminus in-out out-out R09 Type1 24 - 316 7 None None Serine/threonine-protein kinase 10
4USEB 2.65 Inactive DFGin‑ABAminus in-out out-out R09 Type1 24 - 316 6 None None Serine/threonine-protein kinase 10
AF-O94804-K1A -1.0 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 28 - 302 0 None None Serine/threonine-protein kinase 10
AF-O94804-K3A -1.0 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 28 - 302 0 None None Serine/threonine-protein kinase 10
4BC6A 2.2 Inactive DFGin‑BLAminus in-out out-none XZN Type1 24 - 316 8 None None Serine/threonine-protein kinase 10
2J7TA 2.0 Inactive DFGin‑BLAminus in-none out-out 274 Type1 25 - 317 4 None None Serine/threonine-protein kinase 10
5OWRA 2.3 Inactive DFGin‑BLAminus out-out out-none 1N1 Type1 23 - 317 7 None None Serine/threonine-protein kinase 10
6HXFA 2.09 Inactive DFGin‑BLAminus in-in out-out R70 Type1 24 - 313 3 X185,X191,X208 None Serine/threonine-protein kinase 10
6HXFB 2.09 Inactive DFGin‑BLAminus in-in out-out R70 Type1 24 - 314 0 X185,X191,X208 None Serine/threonine-protein kinase 10
6HXFC 2.09 Active DFGin‑BLAminus in-in in-in R70 Type1 24 - 312 0 X185,X191,X208 None Serine/threonine-protein kinase 10
6HXFD 2.09 Inactive DFGin‑BLAminus in-in out-out R70 Type1 23 - 312 0 X185,X191,X208 None Serine/threonine-protein kinase 10
7QGPA 1.9 Inactive DFGin‑BLBminus in-out out-out DJ8 Type1.5_Front 23 - 313 0 None None Serine/threonine-protein kinase 10
5AJQA 2.2 Inactive DFGin‑None out-out out-out DB8 Type1 24 - 312 6 None None Serine/threonine-protein kinase 10
5AJQB 2.2 Inactive DFGin‑None out-none out-none DB8 Type1 25 - 312 13 None None Serine/threonine-protein kinase 10
6GTTA 2.25 Inactive DFGout‑BBAminus in-in none-out B96 Type2 18 - 316 17 None None Serine/threonine-protein kinase 10
6EIMA 1.43 Inactive DFGout‑BBAminus in-in out-out B6E Type2 26 - 317 0 None None Serine/threonine-protein kinase 10
6EIMB 1.43 Inactive DFGout‑BBAminus in-in out-out B6E Type2 23 - 317 0 None None Serine/threonine-protein kinase 10
4AOTA 2.33 Inactive DFGout‑None out-out out-out GW8 Type1 18 - 314 13 None None Serine/threonine-protein kinase 10
4AOTB 2.33 Inactive DFGout‑None out-out out-out GW8 Type1 18 - 314 11 None None Serine/threonine-protein kinase 10
4USDA 3.05 Inactive DFGout‑None out-out none-out R09 Type1 24 - 314 15 None None Serine/threonine-protein kinase 10
4USDB 3.05 Inactive DFGout‑None out-out none-out R09 Type1 24 - 314 15 None None Serine/threonine-protein kinase 10
4EQUA 2.0 Inactive DFGout‑None in-in out-out G6I Type2 24 - 317 9 None None Serine/threonine-protein kinase 10
4EQUB 2.0 Inactive DFGout‑None in-in out-out G6I Type2 24 - 317 8 None None Serine/threonine-protein kinase 10
6I2YA 2.56 Inactive DFGout‑None out-out in-out 88Z Type2 24 - 317 10 None None Serine/threonine-protein kinase 10
6I2YB 2.56 Inactive DFGout‑None out-none out-out 88Z Type2 24 - 317 10 None None Serine/threonine-protein kinase 10
5OWQA 2.7 Inactive None‑None out-none none-none 38O Type1 30 - 317 20 None None Serine/threonine-protein kinase 10
5OWQB 2.7 Inactive None‑None out-out none-none 38O Type1 32 - 317 20 None None Serine/threonine-protein kinase 10

STE_STK10 (Serine/threonine-protein kinase 10)

Total number of chains: 27
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 9 AF-O94804-K1A
DFGin ABAminus 2 4USEA
DFGin BLBminus 1 7QGPA
DFGin None 2 5AJQA
DFGout BBAminus 3 6EIMB
DFGout None 8 4EQUB
None None 2 5OWQB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
STK10_HUMAN 4USEA 2.65 Inactive DFGin‑ABAminus in-out out-out R09 Type1 24 - 316 7 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 4USEB 2.65 Inactive DFGin‑ABAminus in-out out-out R09 Type1 24 - 316 6 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN AF-O94804-K1A -1.0 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 28 - 302 0 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN AF-O94804-K3A -1.0 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 28 - 302 0 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 4BC6A 2.2 Inactive DFGin‑BLAminus in-out out-none XZN Type1 24 - 316 8 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 2J7TA 2.0 Inactive DFGin‑BLAminus in-none out-out 274 Type1 25 - 317 4 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 5OWRA 2.3 Inactive DFGin‑BLAminus out-out out-none 1N1 Type1 23 - 317 7 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 6HXFA 2.09 Inactive DFGin‑BLAminus in-in out-out R70 Type1 24 - 313 3 X185,X191,X208 None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 6HXFB 2.09 Inactive DFGin‑BLAminus in-in out-out R70 Type1 24 - 314 0 X185,X191,X208 None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 6HXFC 2.09 Active DFGin‑BLAminus in-in in-in R70 Type1 24 - 312 0 X185,X191,X208 None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 6HXFD 2.09 Inactive DFGin‑BLAminus in-in out-out R70 Type1 23 - 312 0 X185,X191,X208 None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 7QGPA 1.9 Inactive DFGin‑BLBminus in-out out-out DJ8 Type1.5_Front 23 - 313 0 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 5AJQA 2.2 Inactive DFGin‑None out-out out-out DB8 Type1 24 - 312 6 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 5AJQB 2.2 Inactive DFGin‑None out-none out-none DB8 Type1 25 - 312 13 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 6GTTA 2.25 Inactive DFGout‑BBAminus in-in none-out B96 Type2 18 - 316 17 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 6EIMA 1.43 Inactive DFGout‑BBAminus in-in out-out B6E Type2 26 - 317 0 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 6EIMB 1.43 Inactive DFGout‑BBAminus in-in out-out B6E Type2 23 - 317 0 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 4AOTA 2.33 Inactive DFGout‑None out-out out-out GW8 Type1 18 - 314 13 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 4AOTB 2.33 Inactive DFGout‑None out-out out-out GW8 Type1 18 - 314 11 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 4USDA 3.05 Inactive DFGout‑None out-out none-out R09 Type1 24 - 314 15 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 4USDB 3.05 Inactive DFGout‑None out-out none-out R09 Type1 24 - 314 15 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 4EQUA 2.0 Inactive DFGout‑None in-in out-out G6I Type2 24 - 317 9 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 4EQUB 2.0 Inactive DFGout‑None in-in out-out G6I Type2 24 - 317 8 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 6I2YA 2.56 Inactive DFGout‑None out-out in-out 88Z Type2 24 - 317 10 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 6I2YB 2.56 Inactive DFGout‑None out-none out-out 88Z Type2 24 - 317 10 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 5OWQA 2.7 Inactive None‑None out-none none-none 38O Type1 30 - 317 20 None None Serine/threonine-protein kinase 10 Homo sapiens
STK10_HUMAN 5OWQB 2.7 Inactive None‑None out-out none-none 38O Type1 32 - 317 20 None None Serine/threonine-protein kinase 10 Homo sapiens

STE_STK10 (Serine/threonine-protein kinase 10)

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism