Ligand: 0X2

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 4GFMA
DFGin BLAminus 1 50.0% 4GFOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR JAK2-2 JAK2_HUMAN 4GFMA 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0X2 Type1 840 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR TYK2-2 TYK2_HUMAN 4GFOA 2.3 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai 0X2 Type1 890 - 1176 0 None D1023N Non-receptor tyrosine-protein kinase TYK2

Ligand: 0X2

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 4GFMA
DFGin BLAminus 1 50.0% 4GFOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR JAK2-2 JAK2_HUMAN 4GFMA 2.3 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0X2 Type1 840 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 4GFOA 2.3 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai 0X2 Type1 890 - 1176 0 None D1023N Non-receptor tyrosine-protein kinase TYK2 Homo sapiens

Ligand: 0X2

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism