Protein kinases in complex with MI1 (Tofacitinib)

Total number of genes: 5
Total number of chains: 6
Spatial Dihedral Chains Representative
DFGin BLAplus 1 4OTIA
DFGin ABAminus 5 3LXNA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
AGC PKN1 PKN1_HUMAN Serine/threonine-protein kinase N1 4OTIA 1.93 Inactive DFGin BLAplus in-in none-none MI1 Type1
TYR JAK1 JAK1_HUMAN Tyrosine-protein kinase JAK1 3EYGA 1.9 Inactive DFGin ABAminus in-in in-in MI1 Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 3FUPA 2.4 Inactive DFGin ABAminus in-in in-in MI1 Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 3FUPB 2.4 Inactive DFGin ABAminus in-in in-in MI1 Type1
TYR JAK3 JAK3_HUMAN Tyrosine-protein kinase JAK3 3LXKA 2.0 Inactive DFGin ABAminus in-in in-in MI1 Type1
TYR TYK2 TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 3LXNA 2.5 Inactive DFGin ABAminus in-in in-in MI1 Type1

Protein kinases in complex with MI1

Total number of genes: 5
Total number of chains: 6
Spatial Dihedral Chains Representative
DFGin BLAplus 1 4OTIA
DFGin ABAminus 5 3LXNA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens AGC PKN1 PKN1_HUMAN Serine/threonine-protein kinase N1 4OTIA 1.93 Inactive DFGin BLAplus in-in none-none MI1 Type1
Homo sapiens TYR JAK1 JAK1_HUMAN Tyrosine-protein kinase JAK1 3EYGA 1.9 Inactive DFGin ABAminus in-in in-in MI1 Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 3FUPA 2.4 Inactive DFGin ABAminus in-in in-in MI1 Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 3FUPB 2.4 Inactive DFGin ABAminus in-in in-in MI1 Type1
Homo sapiens TYR JAK3 JAK3_HUMAN Tyrosine-protein kinase JAK3 3LXKA 2.0 Inactive DFGin ABAminus in-in in-in MI1 Type1
Homo sapiens TYR TYK2 TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 3LXNA 2.5 Inactive DFGin ABAminus in-in in-in MI1 Type1

Protein kinases in complex with MI1

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type