CAMK_PRKAA2 (5'-AMP-activated protein kinase catalytic subunit alpha-2)

Total number of chains: 24
Active chains: 1
Uniprot: AAPK2_HUMAN
Kinase Domain Residues: 16 - 268
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 9 37.5% AF-P54646-K3A
DFGin None 6 25.0% 6B1UA
DFGin ABAminus 3 12.5% 5ISOA
None None 3 12.5% 9IC2A
DFGout BBAminus 2 8.3% 2YZAA
DFGin BLBminus 1 4.2% 7MYJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P54646-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 276 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2
5ISOA 2.63 Inactive DFGin‑ABAminus out-none in-out nonTYR APEdihe_aaioi APEdist_iiii STU, 992 Type1, Allosteric 9 - 551 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2
5ISOC 2.63 Inactive DFGin‑ABAminus out-none in-out nonTYR APEdihe_aaioi APEdist_iiii STU, 992 Type1, Allosteric 9 - 550 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2
6B1UC 2.77 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii STU, CG7 Type1, Allosteric 9 - 552 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2
AF-P54646-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 8 - 276 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2
4ZHXA 2.99 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 4O7 Type1 9 - 550 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2
4CFFA 3.924 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioo APEdist_iiii STU Type1 8 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2
8BIKA 2.5 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaioi APEdist_iiii STU, QTN Type1, Allosteric 8 - 551 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2
8BIKD 2.5 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaioi APEdist_iiii STU, QTN Type1, Allosteric 9 - 551 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2
6B2EA 3.8 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaioo APEdist_iiio STU, CG7 Type1, Allosteric 9 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2
4CFEA 3.023 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioo APEdist_iiii STU, 992 Type1, Allosteric 8 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2
4CFEC 3.023 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioo APEdist_iiii STU, 992 Type1, Allosteric 10 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2
7MYJA 2.95 Inactive DFGin‑BLBminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4O7, ZQV Type1, Allosteric 7 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2
7MYJC 2.95 Inactive DFGin‑None out-in in-out nonTYR APEdihe_aaiii APEdist_iooi 4O7 Type1 8 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2
5EZVA 2.99 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU, C1V Type1, Allosteric 8 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2
5EZVC 2.99 Inactive DFGin‑None out-in in-out nonTYR APEdihe_aaioi APEdist_iiii STU, C1V Type1, Allosteric 9 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2
4ZHXC 2.99 Inactive DFGin‑None out-out in-out nonTYR APEdihe_aaoii APEdist_iiio 4O7, C1V Type1, Allosteric 9 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2
6B1UA 2.77 Inactive DFGin‑None out-in in-out nonTYR APEdihe_aaioi APEdist_iiii STU, CG7 Type1, Allosteric 8 - 550 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2
4CFFC 3.924 Inactive DFGin‑None out-out in-out nonTYR APEdihe_aaioo APEdist_iiii STU, C1V Type1, Allosteric 10 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2
2H6DA 1.85 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 10 - 278 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2
2YZAA 3.02 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 10 - 278 0 None T172D 5'-AMP-activated protein kinase catalytic subunit alpha-2
9IC2A 2.5 Inactive None‑None out-out out-out nonTYR APEdihe_aaoii APEdist_nooo A1I1Y Type1 8 - 279 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2
3AQVA 2.08 Inactive None‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn TAK Type1 7 - 279 0 None T172D 5'-AMP-activated protein kinase catalytic subunit alpha-2
6BX6A 2.9 Inactive None‑None out-none out-none nonTYR APEdihe_aannn APEdist_nnnn EDJ Type1 13 - 277 0 None T172D 5'-AMP-activated protein kinase catalytic subunit alpha-2

CAMK_PRKAA2 (5'-AMP-activated protein kinase catalytic subunit alpha-2)

Total number of chains: 24
Active chains: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 9 37.5% AF-P54646-K3A
DFGin None 6 25.0% 6B1UA
DFGin ABAminus 3 12.5% 5ISOA
None None 3 12.5% 9IC2A
DFGout BBAminus 2 8.3% 2YZAA
DFGin BLBminus 1 4.2% 7MYJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AAPK2_HUMAN AF-P54646-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 8 - 276 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 5ISOA 2.63 Inactive DFGin‑ABAminus out-none in-out nonTYR APEdihe_aaioi APEdist_iiii STU, 992 Type1, Allosteric 9 - 551 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 5ISOC 2.63 Inactive DFGin‑ABAminus out-none in-out nonTYR APEdihe_aaioi APEdist_iiii STU, 992 Type1, Allosteric 9 - 550 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 6B1UC 2.77 Inactive DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii STU, CG7 Type1, Allosteric 9 - 552 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN AF-P54646-K1A -1.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 8 - 276 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 4ZHXA 2.99 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 4O7 Type1 9 - 550 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 4CFFA 3.924 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioo APEdist_iiii STU Type1 8 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 8BIKA 2.5 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaioi APEdist_iiii STU, QTN Type1, Allosteric 8 - 551 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 8BIKD 2.5 Inactive DFGin‑BLAminus out-in in-out nonTYR APEdihe_aaioi APEdist_iiii STU, QTN Type1, Allosteric 9 - 551 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 6B2EA 3.8 Inactive DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaioo APEdist_iiio STU, CG7 Type1, Allosteric 9 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 4CFEA 3.023 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioo APEdist_iiii STU, 992 Type1, Allosteric 8 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 4CFEC 3.023 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaioo APEdist_iiii STU, 992 Type1, Allosteric 10 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 7MYJA 2.95 Inactive DFGin‑BLBminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4O7, ZQV Type1, Allosteric 7 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 7MYJC 2.95 Inactive DFGin‑None out-in in-out nonTYR APEdihe_aaiii APEdist_iooi 4O7 Type1 8 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 5EZVA 2.99 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU, C1V Type1, Allosteric 8 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 5EZVC 2.99 Inactive DFGin‑None out-in in-out nonTYR APEdihe_aaioi APEdist_iiii STU, C1V Type1, Allosteric 9 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 4ZHXC 2.99 Inactive DFGin‑None out-out in-out nonTYR APEdihe_aaoii APEdist_iiio 4O7, C1V Type1, Allosteric 9 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 6B1UA 2.77 Inactive DFGin‑None out-in in-out nonTYR APEdihe_aaioi APEdist_iiii STU, CG7 Type1, Allosteric 8 - 550 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 4CFFC 3.924 Inactive DFGin‑None out-out in-out nonTYR APEdihe_aaioo APEdist_iiii STU, C1V Type1, Allosteric 10 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 2H6DA 1.85 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 10 - 278 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 2YZAA 3.02 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 10 - 278 0 None T172D 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 9IC2A 2.5 Inactive None‑None out-out out-out nonTYR APEdihe_aaoii APEdist_nooo A1I1Y Type1 8 - 279 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 3AQVA 2.08 Inactive None‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn TAK Type1 7 - 279 0 None T172D 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
AAPK2_HUMAN 6BX6A 2.9 Inactive None‑None out-none out-none nonTYR APEdihe_aannn APEdist_nnnn EDJ Type1 13 - 277 0 None T172D 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens

CAMK_PRKAA2 (5'-AMP-activated protein kinase catalytic subunit alpha-2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism