Ligand: FZO

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 100.0% 7CHTA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
OTHER TTK TTK_HUMAN 7CHTA 2.4 Inactive DFGin‑ABAminus in-in out-none nonTYR APEdihe_aanni APEdist_nnnn FZO Type1 515 - 794 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK

Ligand: FZO

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 100.0% 7CHTA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER TTK TTK_HUMAN 7CHTA 2.4 Inactive DFGin‑ABAminus in-in out-none nonTYR APEdihe_aanni APEdist_nnnn FZO Type1 515 - 794 0 TPO675,TPO676,SEP677,TPO686 None Dual specificity protein kinase TTK Homo sapiens

Ligand: FZO

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism