Ligand: AME

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 4IWDA
DFGin BLBminus 1 50.0% 3Q6UA
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR MET MET_HUMAN 4IWDA 1.99 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai AME, 1JC Allosteric, Type1 1048 - 1348 0 PTR1234,PTR1235 None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3Q6UA 1.6 Inactive DFGin‑BLBminus in-out none-none TYR APEdihe_nniai APEdist_aaai AME Allosteric 1048 - 1348 0 None None Hepatocyte growth factor receptor

Ligand: AME

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 4IWDA
DFGin BLBminus 1 50.0% 3Q6UA
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR MET MET_HUMAN 4IWDA 1.99 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai AME, 1JC Allosteric, Type1 1048 - 1348 0 PTR1234,PTR1235 None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3Q6UA 1.6 Inactive DFGin‑BLBminus in-out none-none TYR APEdihe_nniai APEdist_aaai AME Allosteric 1048 - 1348 0 None None Hepatocyte growth factor receptor Homo sapiens

Ligand: AME

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism