| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | APEtype | APEdihe | APEdist | Ligand | Ligand Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | PRKACA | KAPCA_HUMAN | 8X5LA | 2.75 | Inactive | DFGin‑ABAminus | in-out | out-out | nonTYR | APEdihe_aaioi | APEdist_iooo | RKD | Type1 | 17 - 351 | 0 | SEP339 | None | cAMP-dependent protein kinase catalytic subunit alpha |
| AGC | PRKACA | KAPCA_HUMAN | 8X5LB | 2.75 | Inactive | DFGin‑ABAminus | out-out | out-out | nonTYR | APEdihe_aaioi | APEdist_iioo | RKD | Type1 | 17 - 334 | 0 | SEP339 | None | cAMP-dependent protein kinase catalytic subunit alpha |
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | APEtype | APEdihe | APEdist | Ligand | Ligand Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | PRKACA | KAPCA_BOVIN | 4AXAA | 1.9 | Inactive | DFGin‑ABAminus | in-in | in-in | nonTYR | APEdihe_aaiii | APEdist_iiii | RKD | Type1 | 15 - 351 | 0 | TPO198,SEP339 | V105T,V124A,L174M,Q182K | cAMP-dependent protein kinase catalytic subunit alpha | Bos taurus |
| AGC | PRKACA | KAPCA_HUMAN | 8X5LA | 2.75 | Inactive | DFGin‑ABAminus | in-out | out-out | nonTYR | APEdihe_aaioi | APEdist_iooo | RKD | Type1 | 17 - 351 | 0 | SEP339 | None | cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens |
| AGC | PRKACA | KAPCA_HUMAN | 8X5LB | 2.75 | Inactive | DFGin‑ABAminus | out-out | out-out | nonTYR | APEdihe_aaioi | APEdist_iioo | RKD | Type1 | 17 - 334 | 0 | SEP339 | None | cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens |
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | APEtype | APEdihe | APEdist | Ligand | Ligand Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | PRKACA | KAPCA_BOVIN | 4AXAA | 1.9 | Inactive | DFGin‑ABAminus | in-in | in-in | nonTYR | APEdihe_aaiii | APEdist_iiii | RKD | Type1 | 15 - 351 | 0 | TPO198,SEP339 | V105T,V124A,L174M,Q182K | cAMP-dependent protein kinase catalytic subunit alpha | Bos taurus |