Protein kinases in complex with H52

Total number of genes: 1
Total number of chains: 2
Spatial Dihedral Chains Representative
DFGin BLAminus 2 3D9VA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
AGC ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 3D9VA 3.3 Active DFGin BLAminus in-in in-in H52 Type1
AGC ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 3D9VB 3.3 Inactive DFGin BLAminus in-in in-out H52 Type1

Protein kinases in complex with H52

Total number of genes: 3
Total number of chains: 7
Spatial Dihedral Chains Representative
DFGin BLAminus 5 1Q8UA
DFGin ABAminus 2 5M6VA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2GNHA 2.05 Inactive DFGin ABAminus in-in in-in H52 H52 Type1 Allosteric
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2GNLA 2.6 Active DFGin BLAminus in-in in-in H52 Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 1Q8UA 1.9 Active DFGin BLAminus in-in in-in H52 H52 Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5M6VA 1.418 Inactive DFGin ABAminus in-in in-in H52 Type1
Dictyostelium discoideum TKL ROCO4 ROCO4_DICDI Probable serine/threonine-protein kinase roco4 4F1TA 2.3 Inactive DFGin BLAminus in-in in-out H52 H52 Type1 Allosteric
Homo sapiens AGC ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 3D9VA 3.3 Active DFGin BLAminus in-in in-in H52 Type1
Homo sapiens AGC ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 3D9VB 3.3 Inactive DFGin BLAminus in-in in-out H52 Type1

Protein kinases in complex with H52

Total number of genes: 2
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAminus 3 1Q8UA
DFGin ABAminus 2 5M6VA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2GNHA 2.05 Inactive DFGin ABAminus in-in in-in H52 H52 Type1 Allosteric
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2GNLA 2.6 Active DFGin BLAminus in-in in-in H52 Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 1Q8UA 1.9 Active DFGin BLAminus in-in in-in H52 H52 Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5M6VA 1.418 Inactive DFGin ABAminus in-in in-in H52 Type1
Dictyostelium discoideum TKL ROCO4 ROCO4_DICDI Probable serine/threonine-protein kinase roco4 4F1TA 2.3 Inactive DFGin BLAminus in-in in-out H52 H52 Type1 Allosteric