TYR_CSK (Tyrosine-protein kinase CSK)

Total number of chains: 6
Active chains: 2
Uniprot: CSK_HUMAN
Kinase Domain Residues: 195 - 442
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 66.7% AF-P41240-K1A
DFGin None 1 16.7% 3D7TA
DFGinter BABtrans 1 16.7% 1BYGA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P41240-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 187 - 450 0 None None Tyrosine-protein kinase CSK
AF-P41240-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 187 - 450 0 None None Tyrosine-protein kinase CSK
3D7TA 2.899 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan STU Type1 188 - 450 0 None K361A,K362A Tyrosine-protein kinase CSK
1BYGA 2.4 Inactive DFGinter‑BABtrans out-out none-none TYR APEdihe_nniai APEdist_aaai STU Type1 187 - 448 0 None None Tyrosine-protein kinase CSK
3D7UA 4.111 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 188 - 450 0 None None Tyrosine-protein kinase CSK
3D7UC 4.111 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 188 - 450 0 None None Tyrosine-protein kinase CSK

TYR_CSK (Tyrosine-protein kinase CSK)

Total number of chains: 12
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 9 75.0% AF-P41240-K1A
DFGin ABAminus 1 8.3% 1K9AB
DFGin None 1 8.3% 3D7TA
DFGinter BABtrans 1 8.3% 1BYGA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CSK_HUMAN AF-P41240-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 187 - 450 0 None None Tyrosine-protein kinase CSK Homo sapiens
CSK_HUMAN AF-P41240-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 187 - 450 0 None None Tyrosine-protein kinase CSK Homo sapiens
CSK_HUMAN 3D7TA 2.899 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan STU Type1 188 - 450 0 None K361A,K362A Tyrosine-protein kinase CSK Homo sapiens
CSK_HUMAN 1BYGA 2.4 Inactive DFGinter‑BABtrans out-out none-none TYR APEdihe_nniai APEdist_aaai STU Type1 187 - 448 0 None None Tyrosine-protein kinase CSK Homo sapiens
CSK_HUMAN 3D7UA 4.111 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 188 - 450 0 None None Tyrosine-protein kinase CSK Homo sapiens
CSK_HUMAN 3D7UC 4.111 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 188 - 450 0 None None Tyrosine-protein kinase CSK Homo sapiens
CSK_RAT 1K9AB 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 4 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus
CSK_RAT 1K9AC 2.5 Inactive DFGin‑BLAminus in-out in-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 6 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus
CSK_RAT 1K9AD 2.5 Inactive DFGin‑BLAminus in-out in-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 6 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus
CSK_RAT 1K9AA 2.5 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 6 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus
CSK_RAT 1K9AE 2.5 None DFGin‑BLAminus in-in in-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 6 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus
CSK_RAT 1K9AF 2.5 None DFGin‑BLAminus in-in in-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 6 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus

TYR_CSK (Tyrosine-protein kinase CSK)

Total number of chains: 6
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 83.3% 1K9AD
DFGin ABAminus 1 16.7% 1K9AB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CSK_RAT 1K9AB 2.5 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 4 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus
CSK_RAT 1K9AC 2.5 Inactive DFGin‑BLAminus in-out in-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 6 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus
CSK_RAT 1K9AD 2.5 Inactive DFGin‑BLAminus in-out in-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 6 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus
CSK_RAT 1K9AA 2.5 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai No_ligand No_ligand 6 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus
CSK_RAT 1K9AE 2.5 None DFGin‑BLAminus in-in in-none TYR APEdihe_nniai APEdist_aaai No_ligand No_ligand 6 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus
CSK_RAT 1K9AF 2.5 None DFGin‑BLAminus in-in in-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 6 - 450 0 None None Tyrosine-protein kinase CSK Rattus norvegicus