Protein kinases in complex with 2V9 (Lestaurtinib)

Total number of genes: 2
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin ABAminus 3 8BPWA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
AGC PKN1 PKN1_HUMAN Serine/threonine-protein kinase N1 4OTGA 2.6 Inactive DFGin ABAminus in-in in-in 2V9 Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 8BPWA 1.8 Inactive DFGin ABAminus in-in in-in 2V9 Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 8BPWB 1.8 Inactive DFGin ABAminus in-in in-in 2V9 Type1

Protein kinases in complex with 2V9

Total number of genes: 3
Total number of chains: 4
Spatial Dihedral Chains Representative
DFGin BLAminus 1 5WNJA
DFGin ABAminus 3 8BPWA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens AGC PKN1 PKN1_HUMAN Serine/threonine-protein kinase N1 4OTGA 2.6 Inactive DFGin ABAminus in-in in-in 2V9 Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 8BPWA 1.8 Inactive DFGin ABAminus in-in in-in 2V9 Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 8BPWB 1.8 Inactive DFGin ABAminus in-in in-in 2V9 Type1
Mus musculus TKL RIPK4 RIPK4_MOUSE Receptor-interacting serine/threonine-protein kinase 4 5WNJA 2.55 Inactive DFGin BLAminus in-in in-out 2V9 Type1

Protein kinases in complex with 2V9

Total number of genes: 1
Total number of chains: 1
Spatial Dihedral Chains Representative
DFGin BLAminus 1 5WNJA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Mus musculus TKL RIPK4 RIPK4_MOUSE Receptor-interacting serine/threonine-protein kinase 4 5WNJA 2.55 Inactive DFGin BLAminus in-in in-out 2V9 Type1