Ligand: DYK

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 4D2SA
DFGin None 1 50.0% 4D2RA
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
OTHER TTK TTK_HUMAN 4D2SA 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-out out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn DYK Type1 513 - 793 0 None None Dual specificity protein kinase TTK
TYR IGF1R IGF1R_HUMAN 4D2RA 2.1 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaai DYK Type1 985 - 1286 0 None None Insulin-like growth factor 1 receptor

Ligand: DYK

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 4D2SA
DFGin None 1 50.0% 4D2RA
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER TTK TTK_HUMAN 4D2SA 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-out out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn DYK Type1 513 - 793 0 None None Dual specificity protein kinase TTK Homo sapiens
TYR IGF1R IGF1R_HUMAN 4D2RA 2.1 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaai DYK Type1 985 - 1286 0 None None Insulin-like growth factor 1 receptor Homo sapiens

Ligand: DYK

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism