Protein kinases in complex with 6ZV

Total number of genes: 4
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAminus 3 7O7KA
DFGin ABAminus 1 7O7JA
DFGin BLBplus 1 5L2SA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC CDK4 CDK4_HUMAN Cyclin-dependent kinase 4 7SJ3A 2.51 Active DFGin BLAminus in-in in-in 6ZV Type1
CMGC CDK6 CDK6_HUMAN Cyclin-dependent kinase 6 5L2SA 2.27 Inactive DFGin BLBplus out-out none-out 6ZV Type1
CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7O7KA 1.82 Active DFGin BLAminus in-in in-in 6ZV LI Type1 Allosteric
CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7O7KB 1.82 Active DFGin BLAminus in-in in-in 6ZV LI Type1 Allosteric
CMGC HIPK3 HIPK3_HUMAN Homeodomain-interacting protein kinase 3 7O7JA 2.81 Inactive DFGin ABAminus in-in in-in 6ZV Type1

Protein kinases in complex with 6ZV

Total number of genes: 4
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAminus 3 7O7KA
DFGin ABAminus 1 7O7JA
DFGin BLBplus 1 5L2SA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC CDK4 CDK4_HUMAN Cyclin-dependent kinase 4 7SJ3A 2.51 Active DFGin BLAminus in-in in-in 6ZV Type1
Homo sapiens CMGC CDK6 CDK6_HUMAN Cyclin-dependent kinase 6 5L2SA 2.27 Inactive DFGin BLBplus out-out none-out 6ZV Type1
Homo sapiens CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7O7KA 1.82 Active DFGin BLAminus in-in in-in 6ZV LI Type1 Allosteric
Homo sapiens CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7O7KB 1.82 Active DFGin BLAminus in-in in-in 6ZV LI Type1 Allosteric
Homo sapiens CMGC HIPK3 HIPK3_HUMAN Homeodomain-interacting protein kinase 3 7O7JA 2.81 Inactive DFGin ABAminus in-in in-in 6ZV Type1

Protein kinases in complex with 6ZV

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type