Protein kinases in complex with 7GI (Repotrectinib)

Total number of genes: 1
Total number of chains: 2
Spatial Dihedral Chains Representative
DFGin ABAminus 1 7VKNA
DFGin None 1 7VKOA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 7VKNA 2.7 Inactive DFGin ABAminus in-out out-in 7GI Type1
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 7VKOA 2.9 Inactive DFGin None in-out out-in 7GI Type1

Protein kinases in complex with 7GI

Total number of genes: 1
Total number of chains: 2
Spatial Dihedral Chains Representative
DFGin ABAminus 1 7VKNA
DFGin None 1 7VKOA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 7VKNA 2.7 Inactive DFGin ABAminus in-out out-in 7GI Type1
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 7VKOA 2.9 Inactive DFGin None in-out out-in 7GI Type1

Protein kinases in complex with 7GI

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type