Ligand: 7GI (Repotrectinib, Augtyro)

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 7VKNA
DFGin None 1 50.0% 7VKOA
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR NTRK1 NTRK1_HUMAN 7VKNA 2.7 Inactive DFGin‑ABAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 7GI Type1 502 - 794 0 None G595R High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 7VKOA 2.9 Inactive DFGin‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 7GI Type1 502 - 793 0 None None High affinity nerve growth factor receptor

Ligand: 7GI (Repotrectinib, Augtyro)

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 7VKNA
DFGin None 1 50.0% 7VKOA
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR NTRK1 NTRK1_HUMAN 7VKNA 2.7 Inactive DFGin‑ABAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 7GI Type1 502 - 794 0 None G595R High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 7VKOA 2.9 Inactive DFGin‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 7GI Type1 502 - 793 0 None None High affinity nerve growth factor receptor Homo sapiens

Ligand: 7GI (Repotrectinib, Augtyro)

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism