Ligand: C15

Total number of chains: 5
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 5 100.0% 6EQ9A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK10 MK10_HUMAN 6EQ9A 1.83 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_nnno ACP, C15 ATPlike, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 8BZPA 1.86 Inactive DFGin‑ABAminus in-none out-out nonTYR APEdihe_aaiii APEdist_onno SWM, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 6EMHA 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 6EMHB 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10
CMGC MAPK10 MK10_HUMAN 8BZPB 1.86 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SWM, C15, C15 Type1, Type1, Allosteric 47 - 400 0 None None Mitogen-activated protein kinase 10

Ligand: C15

Total number of chains: 5
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 5 100.0% 6EQ9A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK10 MK10_HUMAN 6EQ9A 1.83 Inactive DFGin‑ABAminus in-out out-out nonTYR APEdihe_aaiii APEdist_nnno ACP, C15 ATPlike, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 8BZPA 1.86 Inactive DFGin‑ABAminus in-none out-out nonTYR APEdihe_aaiii APEdist_onno SWM, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 6EMHA 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 6EMHB 1.76 Inactive DFGin‑ABAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno BGE, C15 Type1, Allosteric 46 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens
CMGC MAPK10 MK10_HUMAN 8BZPB 1.86 Inactive DFGin‑ABAminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SWM, C15, C15 Type1, Type1, Allosteric 47 - 400 0 None None Mitogen-activated protein kinase 10 Homo sapiens

Ligand: C15

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism