Protein kinases in complex with RRC (Seliciclib)

Total number of genes: 3
Total number of chains: 8
Spatial Dihedral Chains Representative
DFGin BLAminus 4 1UNLA
DFGin ABAminus 1 8BU9H
DFGin BLBminus 1 8FP0A
DFGin BLBtrans 1 2A4LA
DFGin None 1 8BU9B
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BU9H 3.51 Inactive DFGin ABAminus in-in in-in RRC Type1
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BU9E 3.51 Active DFGin BLAminus in-in in-in RRC Type1
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BU9B 3.51 Inactive DFGin None in-in in-in RRC Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3DDQA 1.8 Active DFGin BLAminus in-in in-in RRC Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3DDQC 1.8 Active DFGin BLAminus in-in in-in RRC Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8FP0A 1.6 Inactive DFGin BLBminus out-out out-out RRC 7TW Type1 Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2A4LA 2.4 Inactive DFGin BLBtrans out-out out-out RRC Type1
CMGC CDK5 CDK5_HUMAN Cyclin-dependent kinase 5 1UNLA 2.2 Active DFGin BLAminus in-in in-in RRC Type1

Protein kinases in complex with RRC

Total number of genes: 3
Total number of chains: 8
Spatial Dihedral Chains Representative
DFGin BLAminus 4 1UNLA
DFGin ABAminus 1 8BU9H
DFGin BLBminus 1 8FP0A
DFGin BLBtrans 1 2A4LA
DFGin None 1 8BU9B
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BU9H 3.51 Inactive DFGin ABAminus in-in in-in RRC Type1
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BU9E 3.51 Active DFGin BLAminus in-in in-in RRC Type1
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BU9B 3.51 Inactive DFGin None in-in in-in RRC Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3DDQA 1.8 Active DFGin BLAminus in-in in-in RRC Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3DDQC 1.8 Active DFGin BLAminus in-in in-in RRC Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8FP0A 1.6 Inactive DFGin BLBminus out-out out-out RRC 7TW Type1 Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2A4LA 2.4 Inactive DFGin BLBtrans out-out out-out RRC Type1
Homo sapiens CMGC CDK5 CDK5_HUMAN Cyclin-dependent kinase 5 1UNLA 2.2 Active DFGin BLAminus in-in in-in RRC Type1

Protein kinases in complex with RRC

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type