Ligand: SVE

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 100.0% 5NTTA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
OTHER TTK TTK_HUMAN 5NTTA 2.75 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_oooo SVE Type1 519 - 797 0 TPO686 C604Y Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 5AP7A 2.45 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo SVE Type1 519 - 794 0 None C604W Dual specificity protein kinase TTK
OTHER TTK TTK_HUMAN 2X9EA 3.1 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno SVE Type1 515 - 795 0 None None Dual specificity protein kinase TTK

Ligand: SVE

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 100.0% 5NTTA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER TTK TTK_HUMAN 5NTTA 2.75 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaini APEdist_oooo SVE Type1 519 - 797 0 TPO686 C604Y Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 5AP7A 2.45 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo SVE Type1 519 - 794 0 None C604W Dual specificity protein kinase TTK Homo sapiens
OTHER TTK TTK_HUMAN 2X9EA 3.1 Inactive DFGin‑ABAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno SVE Type1 515 - 795 0 None None Dual specificity protein kinase TTK Homo sapiens

Ligand: SVE

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism