Ligand

Protein kinases in complex with AWJ

Total number of genes: 2

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	ABAminus	2	4CD0A
DFGin	None	2	7Z5XA

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
TYR	ALK	ALK_HUMAN	ALK tyrosine kinase receptor	4CD0A	2.23	Inactive	DFGin	ABAminus	in-in	out-in	AWJ	Type1
TYR	ALK	ALK_HUMAN	ALK tyrosine kinase receptor	7R7RA	1.935	Inactive	DFGin	ABAminus	in-out	out-in	AWJ	Type1
TYR	ROS1	ROS1_HUMAN	Proto-oncogene tyrosine-protein kinase ROS	7Z5XA	2.035	Inactive	DFGin	None	in-in	none-out	AWJ	Type1
TYR	ROS1	ROS1_HUMAN	Proto-oncogene tyrosine-protein kinase ROS	7Z5XB	2.035	Inactive	DFGin	None	in-in	none-out	AWJ	Type1

Protein kinases in complex with AWJ

Total number of genes: 2

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	ABAminus	2	4CD0A
DFGin	None	2	7Z5XA

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	TYR	ALK	ALK_HUMAN	ALK tyrosine kinase receptor	4CD0A	2.23	Inactive	DFGin	ABAminus	in-in	out-in	AWJ	Type1
Homo sapiens	TYR	ALK	ALK_HUMAN	ALK tyrosine kinase receptor	7R7RA	1.935	Inactive	DFGin	ABAminus	in-out	out-in	AWJ	Type1
Homo sapiens	TYR	ROS1	ROS1_HUMAN	Proto-oncogene tyrosine-protein kinase ROS	7Z5XA	2.035	Inactive	DFGin	None	in-in	none-out	AWJ	Type1
Homo sapiens	TYR	ROS1	ROS1_HUMAN	Proto-oncogene tyrosine-protein kinase ROS	7Z5XB	2.035	Inactive	DFGin	None	in-in	none-out	AWJ	Type1

Protein kinases in complex with AWJ

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type