WEE1 (Wee1-like protein kinase)

Group: OTHER
Uniprot: WEE1_HUMAN
Domain boundary: 299 - 569


Total number of chains: 24
Spatial Dihedral Chains Representative
DFGin BLAminus 24 AF-P30291-K1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
8WDKW 3.64 Inactive DFGin BLAminus out-out in-in No_ligand No_ligand 293 - 569 None None 0
AF-P30291-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 291 - 577 None None 0
2Z2WA 2.22 Active DFGin BLAminus in-in in-in 770 Type1 291 - 571 None None 0
7N3UA 2.65 Inactive DFGin BLAminus out-out in-in 05J Type1 293 - 570 None None 0
8BJUA 1.53 Inactive DFGin BLAminus in-out in-in QT9 Type1 293 - 571 None None 0
2IN6A 1.9 Active DFGin BLAminus in-in in-in 839 Type1 291 - 569 None None 0
2IO6A 2.2 Active DFGin BLAminus in-in in-in 330 Type1 291 - 569 None None 0
3BI6A 2.2 Inactive DFGin BLAminus in-out in-in 396 Type1 293 - 570 None None 0
3BIZA 2.2 Active DFGin BLAminus in-in in-in 61E Type1 293 - 569 None None 0
3CQEA 2.5 Inactive DFGin BLAminus in-out in-in P91 Type1 293 - 570 None None 0
3CR0A 2.3 Inactive DFGin BLAminus in-out in-in 809 Type1 293 - 573 None None 0
5V5YA 1.9 Active DFGin BLAminus in-in in-in 8X7 Type1 293 - 569 None None 0
5VC3A 1.97 Inactive DFGin BLAminus out-out in-in DB8 Type1 293 - 570 None None 0
5VC4A 2.1 Inactive DFGin BLAminus in-out in-in XZN Type1 293 - 571 None None 0
5VC5A 1.93 Inactive DFGin BLAminus in-out in-in 96M Type1 293 - 571 None None 0
5VC6A 2.0 Active DFGin BLAminus in-in in-in P48 Type1 293 - 571 None None 0
5VD2A 2.05 Inactive DFGin BLAminus out-out in-in 34W Type1 293 - 569 None None 0
5VD4A 2.02 Active DFGin BLAminus in-in in-in 99J Type1 293 - 571 None None 0
5VD5A 2.05 Active DFGin BLAminus in-in in-in 99M Type1 293 - 571 None None 0
5VD7A 2.08 Active DFGin BLAminus in-in in-in 99V Type1 293 - 571 None None 0
5VD8A 1.85 Active DFGin BLAminus in-in in-in 98M Type1 293 - 571 None None 0
5VD9A 1.87 Inactive DFGin BLAminus in-out in-in 98G Type1 292 - 571 None None 0
5VDAA 2.1 Inactive DFGin BLAminus in-out in-in 98D Type1 293 - 571 None None 0
1X8BA 1.81 Active DFGin BLAminus in-in in-in 824 Type1 291 - 569 None None 0

WEE1 (Wee1-like protein kinase)

Group: OTHER
Total number of chains: 24
Spatial Dihedral Chains Representative
DFGin BLAminus 24 AF-P30291-K1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens WEE1_HUMAN 8WDKW 3.64 Inactive DFGin BLAminus out-out in-in No_ligand No_ligand 293 - 569 None None 0
Homo sapiens WEE1_HUMAN AF-P30291-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 291 - 577 None None 0
Homo sapiens WEE1_HUMAN 2Z2WA 2.22 Active DFGin BLAminus in-in in-in 770 Type1 291 - 571 None None 0
Homo sapiens WEE1_HUMAN 7N3UA 2.65 Inactive DFGin BLAminus out-out in-in 05J Type1 293 - 570 None None 0
Homo sapiens WEE1_HUMAN 8BJUA 1.53 Inactive DFGin BLAminus in-out in-in QT9 Type1 293 - 571 None None 0
Homo sapiens WEE1_HUMAN 2IN6A 1.9 Active DFGin BLAminus in-in in-in 839 Type1 291 - 569 None None 0
Homo sapiens WEE1_HUMAN 2IO6A 2.2 Active DFGin BLAminus in-in in-in 330 Type1 291 - 569 None None 0
Homo sapiens WEE1_HUMAN 3BI6A 2.2 Inactive DFGin BLAminus in-out in-in 396 Type1 293 - 570 None None 0
Homo sapiens WEE1_HUMAN 3BIZA 2.2 Active DFGin BLAminus in-in in-in 61E Type1 293 - 569 None None 0
Homo sapiens WEE1_HUMAN 3CQEA 2.5 Inactive DFGin BLAminus in-out in-in P91 Type1 293 - 570 None None 0
Homo sapiens WEE1_HUMAN 3CR0A 2.3 Inactive DFGin BLAminus in-out in-in 809 Type1 293 - 573 None None 0
Homo sapiens WEE1_HUMAN 5V5YA 1.9 Active DFGin BLAminus in-in in-in 8X7 Type1 293 - 569 None None 0
Homo sapiens WEE1_HUMAN 5VC3A 1.97 Inactive DFGin BLAminus out-out in-in DB8 Type1 293 - 570 None None 0
Homo sapiens WEE1_HUMAN 5VC4A 2.1 Inactive DFGin BLAminus in-out in-in XZN Type1 293 - 571 None None 0
Homo sapiens WEE1_HUMAN 5VC5A 1.93 Inactive DFGin BLAminus in-out in-in 96M Type1 293 - 571 None None 0
Homo sapiens WEE1_HUMAN 5VC6A 2.0 Active DFGin BLAminus in-in in-in P48 Type1 293 - 571 None None 0
Homo sapiens WEE1_HUMAN 5VD2A 2.05 Inactive DFGin BLAminus out-out in-in 34W Type1 293 - 569 None None 0
Homo sapiens WEE1_HUMAN 5VD4A 2.02 Active DFGin BLAminus in-in in-in 99J Type1 293 - 571 None None 0
Homo sapiens WEE1_HUMAN 5VD5A 2.05 Active DFGin BLAminus in-in in-in 99M Type1 293 - 571 None None 0
Homo sapiens WEE1_HUMAN 5VD7A 2.08 Active DFGin BLAminus in-in in-in 99V Type1 293 - 571 None None 0
Homo sapiens WEE1_HUMAN 5VD8A 1.85 Active DFGin BLAminus in-in in-in 98M Type1 293 - 571 None None 0
Homo sapiens WEE1_HUMAN 5VD9A 1.87 Inactive DFGin BLAminus in-out in-in 98G Type1 292 - 571 None None 0
Homo sapiens WEE1_HUMAN 5VDAA 2.1 Inactive DFGin BLAminus in-out in-in 98D Type1 293 - 571 None None 0
Homo sapiens WEE1_HUMAN 1X8BA 1.81 Active DFGin BLAminus in-in in-in 824 Type1 291 - 569 None None 0

WEE1 (Wee1-like protein kinase)

No non-human structures known.