Ligand: LWX

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 75.0% 8HMTA
DFGin None 1 25.0% 8HMTD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR TNK2 ACK1_HUMAN 8HMTA 3.17 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 8HMTB 3.17 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai LWX Type1.5_Back 117 - 388 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 8HMTC 3.17 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 8HMTD 3.17 Inactive DFGin‑None in-out in-in TYR APEdihe_iiiai APEdist_aaai LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1

Ligand: LWX

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 75.0% 8HMTA
DFGin None 1 25.0% 8HMTD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR TNK2 ACK1_HUMAN 8HMTA 3.17 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 8HMTB 3.17 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai LWX Type1.5_Back 117 - 388 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 8HMTC 3.17 Inactive DFGin‑ABAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1 Homo sapiens
TYR TNK2 ACK1_HUMAN 8HMTD 3.17 Inactive DFGin‑None in-out in-in TYR APEdihe_iiiai APEdist_aaai LWX Type1.5_Back 117 - 389 0 None None Activated CDC42 kinase 1 Homo sapiens

Ligand: LWX

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism