Ligand: FEF

Total number of chains: 6
Active chains: 2
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 50.0% 4C57A
DFGin BLAminus 2 33.3% 2VZ6B
DFGout None 1 16.7% 3MTLA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK CAMK2A KCC2A_HUMAN 2VZ6A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 9 - 299 0 None None Calcium/calmodulin-dependent protein kinase type II subunit alpha
CAMK CAMK2A KCC2A_HUMAN 2VZ6B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 9 - 300 0 None None Calcium/calmodulin-dependent protein kinase type II subunit alpha
CMGC CDK16 CDK16_HUMAN 3MTLA 2.4 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn FEF Type1 163 - 473 0 None S319D Cyclin-dependent kinase 16
OTHER GAK GAK_HUMAN 4C57A 2.55 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 25 - 334 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 4C57B 2.55 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 27 - 334 0 None None Cyclin-G-associated kinase
OTHER GAK GAK_HUMAN 4C59A 2.8 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn FEF Type1 27 - 333 0 None None Cyclin-G-associated kinase

Ligand: FEF

Total number of chains: 6
Active chains: 2
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 50.0% 4C57A
DFGin BLAminus 2 33.3% 2VZ6B
DFGout None 1 16.7% 3MTLA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK CAMK2A KCC2A_HUMAN 2VZ6A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 9 - 299 0 None None Calcium/calmodulin-dependent protein kinase type II subunit alpha Homo sapiens
CAMK CAMK2A KCC2A_HUMAN 2VZ6B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 9 - 300 0 None None Calcium/calmodulin-dependent protein kinase type II subunit alpha Homo sapiens
CMGC CDK16 CDK16_HUMAN 3MTLA 2.4 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn FEF Type1 163 - 473 0 None S319D Cyclin-dependent kinase 16 Homo sapiens
OTHER GAK GAK_HUMAN 4C57A 2.55 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 25 - 334 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 4C57B 2.55 Inactive DFGin‑ABAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii FEF Type1 27 - 334 0 None None Cyclin-G-associated kinase Homo sapiens
OTHER GAK GAK_HUMAN 4C59A 2.8 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn FEF Type1 27 - 333 0 None None Cyclin-G-associated kinase Homo sapiens

Ligand: FEF

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism