Protein kinases in complex with C87 (Momelotinib)

Total number of genes: 3
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 1 7NNSB
DFGin ABAminus 1 8BXHA
DFGout BBAminus 1 6FDZU
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
OTHER ULK3 ULK3_HUMAN Serine/threonine-protein kinase ULK3 6FDZU 2.55 Inactive DFGout BBAminus out-out out-out C87 Type1
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 7NNSB 2.14 Inactive DFGin BLAminus in-out in-in C87 Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 8BXHA 1.3 Inactive DFGin ABAminus in-in in-in C87 Type1

Protein kinases in complex with C87

Total number of genes: 3
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 1 7NNSB
DFGin ABAminus 1 8BXHA
DFGout BBAminus 1 6FDZU
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens OTHER ULK3 ULK3_HUMAN Serine/threonine-protein kinase ULK3 6FDZU 2.55 Inactive DFGout BBAminus out-out out-out C87 Type1
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 7NNSB 2.14 Inactive DFGin BLAminus in-out in-in C87 Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 8BXHA 1.3 Inactive DFGin ABAminus in-in in-in C87 Type1

Protein kinases in complex with C87

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type