Ligand: NK3

Total number of chains: 8
Active chains: 0
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 6 75.0% 7UKZB
DFGin BLAminus 2 25.0% 9QJJB

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK11B CD11B_HUMAN 7UKZA 2.6 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B
CMGC CDK11B CD11B_HUMAN 7UKZB 2.6 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B
CMGC CDK11B CD11B_HUMAN 7UKZC 2.6 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B
CMGC CDK11B CD11B_HUMAN 7UKZD 2.6 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 437 - 736 0 TPO595 None Cyclin-dependent kinase 11B
CMGC CDK11B CD11B_HUMAN 7UKZE 2.6 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 435 - 736 0 TPO595 None Cyclin-dependent kinase 11B
CMGC CDK11B CD11B_HUMAN 7UKZF 2.6 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B
CMGC CDK2 CDK2_HUMAN 9QJJB 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn NK3 Type1 1 - 296 0 None None Cyclin-dependent kinase 2
CMGC CDK7 CDK7_HUMAN 9QJNJ 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iiii NK3 Type1 10 - 310 0 None None Cyclin-dependent kinase 7

Ligand: NK3

Total number of chains: 8
Active chains: 0
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 6 75.0% 7UKZB
DFGin BLAminus 2 25.0% 9QJJB

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK11B CD11B_HUMAN 7UKZA 2.6 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B Homo sapiens
CMGC CDK11B CD11B_HUMAN 7UKZB 2.6 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B Homo sapiens
CMGC CDK11B CD11B_HUMAN 7UKZC 2.6 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B Homo sapiens
CMGC CDK11B CD11B_HUMAN 7UKZD 2.6 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 437 - 736 0 TPO595 None Cyclin-dependent kinase 11B Homo sapiens
CMGC CDK11B CD11B_HUMAN 7UKZE 2.6 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 435 - 736 0 TPO595 None Cyclin-dependent kinase 11B Homo sapiens
CMGC CDK11B CD11B_HUMAN 7UKZF 2.6 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-in nonTYR APEdihe_aaiii APEdist_iiii NK3 Type1 436 - 736 0 TPO595 None Cyclin-dependent kinase 11B Homo sapiens
CMGC CDK2 CDK2_HUMAN 9QJJB 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn NK3 Type1 1 - 296 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK7 CDK7_HUMAN 9QJNJ 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaioi APEdist_iiii NK3 Type1 10 - 310 0 None None Cyclin-dependent kinase 7 Homo sapiens

Ligand: NK3

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism