9ESA

AURKC (Aurora kinase C)
Group: CAMK
Uniprot: AURKC_HUMAN
Organism: Homo sapiens
Domain boundary: 43 - 293
Resolu: 2.8

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
AAA Inactive DFGin ABAminus out-out out-out No_ligand No_ligand 32 - 306 0
BBB Inactive DFGin ABAminus out-out out-out No_ligand No_ligand 32 - 306 0
Representative sequence - Chain BBB
16 26 36 46
hhhhhhaqpa geelatanqt aqqpsSPAMR RLTVDDFEIG
56 66 76 86
RPLGKGKFGN VYLARLKESH FIVALKVLFK SQIEKEGLEH
96 106 116 126
QLRREIEIQA HLQHPNILRL YNYFHDARRV YLILEYAPRG
136 146 156 166
ELYKELQKSE KLDEQRTATI IEELADALTY CHDKKVIHRD
176 186 196 206
IKPENLLLGF RGEVKIADFG WSVHTPSLAA ATMCGTLDYL
216 226 236 246
PPEMIEGRTY DEKVDLWCIG VLCYELLVGY PPFESASHSE
256 266 276 286
TYRRILKVDV RFPLSMPLGA RDLISRLLRY QPLERLPLAQ
296 306
ILKHPWVQAH SRRVLPPCAQ mas
Lower-case residues are disordered in structure.
Mutations: R195A,R196A,K197A
Phosphorylation: None