Ligand

Protein kinases in complex with 537

Total number of genes: 4

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	5LVLA
DFGin	ABAminus	2	1UKIA
DFGin	None	1	1PMVA

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
AGC	PDPK1	PDPK1_HUMAN	3-phosphoinositide-dependent protein kinase 1	5LVLA	1.4	Active	DFGin	BLAminus	in-in	in-in	537	Type1
CMGC	MAPK10	MK10_HUMAN	Mitogen-activated protein kinase 10	1PMVA	2.5	Inactive	DFGin	None	out-out	none-out	537	Type1
CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	1UKIA	2.7	Inactive	DFGin	ABAminus	in-in	out-none	537	Type1
OTHER	TTK	TTK_HUMAN	Dual specificity protein kinase TTK	2ZMDA	2.88	Inactive	DFGin	ABAminus	out-out	out-out	537	Type1

Protein kinases in complex with 537

Total number of genes: 4

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	5LVLA
DFGin	ABAminus	2	1UKIA
DFGin	None	1	1PMVA

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	AGC	PDPK1	PDPK1_HUMAN	3-phosphoinositide-dependent protein kinase 1	5LVLA	1.4	Active	DFGin	BLAminus	in-in	in-in	537	Type1
Homo sapiens	CMGC	MAPK10	MK10_HUMAN	Mitogen-activated protein kinase 10	1PMVA	2.5	Inactive	DFGin	None	out-out	none-out	537	Type1
Homo sapiens	CMGC	MAPK8	MK08_HUMAN	Mitogen-activated protein kinase 8	1UKIA	2.7	Inactive	DFGin	ABAminus	in-in	out-none	537	Type1
Homo sapiens	OTHER	TTK	TTK_HUMAN	Dual specificity protein kinase TTK	2ZMDA	2.88	Inactive	DFGin	ABAminus	out-out	out-out	537	Type1

Protein kinases in complex with 537

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type